| Literature DB >> 32965735 |
Nicole E Andrews1,2,3, Chi-Wen Chien4, David Ireland5, Marlien Varnfield5.
Abstract
BACKGROUND: Overactivity in the context of chronic pain (i.e. activity engagement that significantly exacerbates pain) is an important clinical issue that has gained empirical attention in the last decade. Current assessment concepts of overactivity tend to focus on frequency to quantify the severity of the pain behaviour. This study aimed to develop and validate a more comprehensive self-assessment, the Overactivity in Persistent Pain Assessment (OPPA).Entities:
Mesh:
Year: 2020 PMID: 32965735 PMCID: PMC7821341 DOI: 10.1002/ejp.1664
Source DB: PubMed Journal: Eur J Pain ISSN: 1090-3801 Impact factor: 3.931
Hypothesized associations between overactivity severity measured using the OPPA and pain measures
| Direction | Strength | Rationale | |
|---|---|---|---|
| Other overactivity measures | Positive | Moderate | Based on the assumption that other measures provide an incomplete assessment of the overactivity construct i.e. they should be related to the OPPA but not strongly |
| Activity avoidance | Positive | Small | Overactivity is theorized to result in increased activity avoidance overtime (Birkholtz et al., |
| Activity pacing | No Association | No Association | Overactive individuals have described either infrequent use of activity pacing strategies or using pacing strategies regularly but ineffectively (Andrews et al., |
| Depression | Positive | Moderate | Overactivity behaviour has been theorized to significantly worsen pain severity, mood, sleep quality and disrupt normal activity participation (Birkholtz et al., |
| Anxiety | Positive | Moderate | |
| Stress | Positive | Moderate | |
| Pain severity | Positive | Moderate | |
| Pain interference | Positive | Moderate | |
| Activity participation | Negative | Moderate |
No association r < 0.1; Small association r = 0.1–0.29, Moderate association r = 0.30–0.49 (Cohen, 1988; Statistical Solutions, 2020).
FIGURE 1The deconstruction of the overactivity construct in a graphical form
Final items and responses for the overactivity in persistent pain assessment (OPPA)
FIGURE 2Flow of participants through the different phases of the study
Characteristics of the study populations
| Demographic variable | Total % ( | Construct validity sample % ( | Test–retest reliability responders % ( | Test–retest reliability non‐responders % ( |
|---|---|---|---|---|
| Gender | ||||
| Male | 38.7 (129) | 37.1 (75) | 39.7 (25) | 42.6 (29) |
| Female | 61.3 (204) | 62.9 (127) | 60.3 (38) | 57.4 (39) |
| Age (years) | 50.3 (17–84) | 52.4 (19–78) | 52.67 (19–84) | 42.03 (17–76) |
| Pain Duration (years) | 12.2 (0.6–50) | 12.7 (0.8–49) | 11.85 (0.6–50) | 11.1 (0.6–50) |
| Pain Location (incidence) | ||||
| Head/face | 15.6 (52) | 16.3 (33) | 14.3 (9) | 13.2 (9) |
| Upper limb | 34.7 (116) | 33.7 (68) | 34.9 (22) | 38.2 (26) |
| Neck | 35.3 (118) | 36.1 (73) | 34.9 (22) | 32.4 (22) |
| Upper back | 34.7 (116) | 27.2 (55) | 20.6 (13) | 32.4 (22) |
| Lower back | 69.5 (232) | 72.8 (147) | 63.5 (40) | 66.2 (45) |
| Chest | 9.6 (32) | 8.9 (18) | 6.3 (4) | 14.7 (10) |
| Abdomen/groin | 20.7 (69) | 17.8 (36) | 23.8 (15) | 26.5 (18) |
| Lower limb | 54.5 (182) | 54.0 (109) | 54.0 (34) | 58.8 (40) |
| Total body | 3.6 (12) | 3.5 (7) | 4.8 (3) | 2.9 (2) |
| Average pain intensity | 5.97 (0–10) | 5.96 (1–10) | 6.05 (2–10) | 5.95 (0–10) |
| Living situation | ||||
| With partner | 53.3 (178) | 55.0 (111) | 55.6 (35) | 47.1 (32) |
| With children | 24 (80) | 24.3 (49) | 15.9 (10) | 30.9 (21) |
| With other family | 12 (40) | 11.9 (24) | 9.5 (6) | 14.7 (10) |
| With friends/flatmate | 9 (30) | 7.9 (16) | 15.9 (10) | 5.9 (4) |
| Lives alone | 20.7 (69) | 20.8 (42) | 19 (12) | 20.6 (14) |
| Education level | ||||
| Primary school | 4.2 (14) | 3.0 (6) | 7.9 (5) | 4.4 (3) |
| Junior high school | 25.4 (85) | 27.7 (56) | 22.2 (14) | 22.1 (15) |
| Senior high school | 24.6 (82) | 22.3 (45) | 28.6 (18) | 27.9 (19) |
| Tertiary non‐university | 27.5 (92) | 27.7 (56) | 25.4 (16) | 29.4 (20) |
| Tertiary university | 18.0 (60) | 19.3 (39) | 14.3 (9) | 16.2 (11) |
| Employment status | ||||
| Employed full‐time | 14.4 (48) | 13.4 (27) | 7.9 (5) | 23.5 (16) |
| Employed part‐time | 11.4 (38) | 12.4 (25) | 12.7 (8) | 7.4 (5) |
| Retired | 18.3 (61) | 21.3 (43) | 23.8 (15) | 4.4 (3) |
| Home duties/carer | 5.1 (17) | 4.5 (9) | 6.3 (4) | 5.9 (4) |
| Unemployed due to pain | 44.3 (148) | 42.1 (85) | 36.5 (23) | 55.9 (38) |
| Unemployed other reasons | 6.6 (22) | 6.4 (13) | 11.1 (7) | 2.9 (2) |
| Denied overactivity tendencies | 9.3 (31) | 6.9 (14) | 15.9 (10) | 10.3 (7) |
Values = Mean (Range).
Component loadings and communalities based on a principal component analysis (N = 333)
| Item | Component loading | Communalities |
|---|---|---|
| Frequency: How often do you aggravate (e.g. worsen) your pain by doing too much? | 0.84 | 0.71 |
| Severity of Pain Aggravation: Please rate typically how much pain you are in after you have done too much? | 0.61 | 0.37 |
| Impact on Occupational Performance: What are you normally like after you have done too much? | 0.83 | 0.69 |
| Recovery Time: How long does it normally take you to recover after you have done too much? | 0.82 | 0.67 |
| Maladaptive Coping: Please indicate if you ever do any of the following after you have done too much? | 0.54 | 0.29 |
Means, standard deviation values and correlations between the OPPA scores and existing measures of overactivity
|
| Floor Effect | Ceiling Effect | Mean ( |
PARQ Confronting ρ (p) |
POAM‐P Overdoing ρ (p) | |
|---|---|---|---|---|---|---|
| PARQ confronting | 199 | – | – | 3.34 (0.73) | ||
| POAM‐P overdoing | 191 | – | – | 24.08 (7.68) | 0.75 (<0.001) | |
| OPPA frequency | 202 | 6.9 | 53 | 4.03 (1.46) | 0.35 (<0.001) | 0.21 (0.004) |
| OPPA severity of pain aggravation | 202 | 0.5 | 12.9 | 3.99 (0.74) | 0.15 (0.03) | 0.10 (0.16) |
| OPPA impact on occupational performance | 202 | 6.9 | 4.5 | 2.88 (1.28) | 0.08 (0.26) | 0.13 (0.08) |
| OPPA recovery time | 202 | 6.9 | 15.8 | 3.26 (1.29) | 0.10 (0.16) | 0.01 (0.85) |
| OPPA maladaptive coping | 202 | 30.7 | 2.0 | 1.63 (1.29) | 0.00 (0.99) | 0.08 (0.30) |
| OPPA total | 202 | 0.0 | 0.0 | 15.80 (4.36) | 0.17 (0.02) | 0.15 (0.04) |
OPPA, overactivity in persistent pain assessment; PARQ, pain and activity relations questionnaire; POAM‐P, patterns of activity measure‐pain.
Percentage of sample that were given the lowest possible score.
Percentage of the sample that were given the highest possible score.
Means, standard deviation values and correlations between the OPPA total score and measures of pacing, activity avoidance, negative affect, pain‐related disability and pain severity
|
| Mean ( |
OPPA total ρ (p) | |
|---|---|---|---|
| PARQ avoidance | 199 | 3.04 (0.95) | 0.20 (0.005) |
| POAM‐P avoidance | 191 | 23.17 (7.79) | 0.21 (0.003) |
| PARQ pacing | 199 | 3.22 (0.98) | −0.08 (0.26) |
| POAM‐P pacing | 191 | 22.34 (0.73) | 0.03 (0.68) |
| DASS−21 depression | 201 | 16.49 (12.06) | 0.30 (<0.001) |
| DASS−21 anxiety | 201 | 13.23 (10.36) | 0.23 (0.001) |
| DASS−21 stress | 201 | 18.11 (10.86) | 0.35 (<0.001) |
| DASS−21 total | 201 | 47.83 (29.99) | 0.33 (<0.001) |
| WHYMPI pain severity | 197 | 4.23 (1.07) | 0.41 (<0.001) |
| WHYMPI interference | 197 | 4.15 (0.91) | 0.40 (<0.001) |
| WHYMPI household chores | 198 | 3.80 (1.35) | −0.20 (0.005) |
| WHYMPI outdoor work | 198 | 1.38 (1.40) | −0.18 (0.01) |
| WHYMPI activities away from home | 198 | 2.34 (1.10) | −0.26 (<0.001) |
| WHYMPI social activities | 198 | 2.14 (1.17) | −0.19 (0.007) |
| WHYMPI general activity | 198 | 2.41 (0.96) | −0.28 (<0.001) |
Abbreviations: DASS‐21, 21 item depression anxiety stress scales; OPPA, overactivity in persistent pain assessment; PARQ, pain and activity relations questionnaire; POAM‐P, patterns of activity measure‐pain; WHYMPI, west haven‐yale multidimensional pain inventory.
Summary of hierarchical regression analysis for psychology functioning, pain interference, activity participation and pain severity
| Dependent variable | Model/step | Variables | β |
|
|
|
|---|---|---|---|---|---|---|
| DASS−21 total | All models: Step 1 | PARQ avoidance | 0.26 | 0.10 | 0.10 | 7.12 |
| Gender | 0.06 | |||||
| Age | −0.16 | |||||
| Model 1: Step 2 | OPPA Total | 0.23 | 0.15 | 0.05 | 11.43 | |
| PARQ Avoidance | 0.22 | |||||
| Gender | 0.14 | |||||
| Age | −0.13 | |||||
| Model 2: Step 2 | PARQ Confronting | 0.18 | 0.13 | 0.03 | 6.99 | |
| PARQ Avoidance | 0.27 | |||||
| Gender | 0.02 | |||||
| Age | −0.15 | |||||
| Model 3: Step 2 | POAM‐P Overdoing | 0.27 | 0.18 | 0.07 | 16.02 | |
| PARQ Avoidance | 0.28 | |||||
| Gender | 0.05 | |||||
| Age | −0.15 | |||||
| WHYMPI Pain Severity | All Models: Step 1 | PARQ Avoidance | 0.39 | 0.16 | 0.16 | 11.77 |
| Gender | −0.06 | |||||
| Age | −0.05 | |||||
| Model 1: Step 2 | OPPA Total | 0.40 | 0.30 | 0.15 | 39.75 | |
| PARQ Avoidance | 0.32 | |||||
| Gender | −0.12 | |||||
| Age | 0.01 | |||||
| Model 2: Step 2 | PARQ Confronting | 0.08 | 0.16 | 0.01 | 1.39 | |
| PARQ Avoidance | 0.40 | |||||
| Gender | −0.07 | |||||
| Age | −0.05 | |||||
| Model 3: Step 2 | POAM‐P Overdoing | 0.09 | 0.16 | 0.01 | 1.81 | |
| PARQ Avoidance | 0.39 | |||||
| Gender | −0.06 | |||||
| Age | −0.03 | |||||
| WHYMPI Interference | All models: Step 1 | PARQ Avoidance | 0.21 | 0.05 | 0.05 | 3.12 |
| Gender | 0.01 | |||||
| Age | −0.04 | |||||
| Model 1: Step 2 | OPPA Total | 0.30 | 0.13 | 0.08 | 18.03 | |
| PARQ Avoidance | 0.16 | |||||
| Gender | −0.04 | |||||
| Age | −0.01 | |||||
| Model 2: Step 2 | PARQ Confronting | 0.12 | 0.06 | 0.01 | 2.55 | |
| PARQ Avoidance | 0.22 | |||||
| Gender | −0.02 | |||||
| Age | −0.04 | |||||
| Model 3: Step 3 | POAM‐P overdoing | 0.08 | 0.06 | 0.01 | 1.31 | |
| PARQ avoidance | 0.23 | |||||
| Gender | −0.01 | |||||
| Age | −0.02 | |||||
| WHYMPI general activity | All models: Step 1 | PARQ avoidance | −0.25 | 0.07 | 0.07 | 5.04 |
| Gender | −0.10 | |||||
| Age | −0.03 | |||||
| Model 1: Step 2 | OPPA Total | −0.17 | 0.10 | 0.03 | 5.26 | |
| PARQ Avoidance | −0.22 | |||||
| Gender | −0.08 | |||||
| Age | −0.05 | |||||
| Model 2: Step 2 | PARQ confronting | 0.12 | 0.09 | 0.01 | 2.80 | |
| PARQ avoidance | −0.24 | |||||
| Gender | −0.12 | |||||
| Age | −0.03 | |||||
| Model 3: Step 2 | POAM‐P overdoing | 0.09 | 0.07 | 0.01 | 1.56 | |
| PARQ avoidance | −0.23 | |||||
| Gender | −0.10 | |||||
| Age | −0.03 |
Abbreviations: DASS‐21, 21 item depression anxiety stress scales; OPPA, overactivity in persistent pain assessment; PARQ, pain and activity relations questionnaire; POAM‐P, patterns of activity measure‐pain; WHYMPI, west haven‐yale multidimensional pain inventory.
p < 0.05.
p < 0.01.
FIGURE 3Bland‐Altman plot illustrating the level of agreement between baseline and 1‐week OPPA scores