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Literature DB >> 32965657

Totally tubular, dude: rethinking DKD pathogenesis in the wake of SGLT2i data.

Samuel Mon-Wei Yu¹, Jeremy S Leventhal², Paolo Cravedi³.

Abstract

Entities: Gene

Keywords: Autophagy; Diabetic kidney disease; Proximal tubule; Sodium glucose co-transporter 2; Tubuloglomerular feedback

Year: 2021 PMID： 32965657 DOI： 10.1007/s40620-020-00868-0

Source DB: PubMed Journal: J Nephrol ISSN： 1121-8428 Impact factor: 3.902

× No keyword cloud information.

9 in total

Review 1. Role of Impaired Nutrient and Oxygen Deprivation Signaling and Deficient Autophagic Flux in Diabetic CKD Development: Implications for Understanding the Effects of Sodium-Glucose Cotransporter 2-Inhibitors.

Authors: Milton Packer
Journal: J Am Soc Nephrol Date: 2020-04-10 Impact factor: 10.121

2. SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition.

Authors: Issei Tomita; Shinji Kume; Sho Sugahara; Norihisa Osawa; Kosuke Yamahara; Mako Yasuda-Yamahara; Naoko Takeda; Masami Chin-Kanasaki; Tatsuroh Kaneko; Eric Mayoux; Michael Mark; Motoko Yanagita; Hisakazu Ogita; Shin-Ichi Araki; Hiroshi Maegawa
Journal: Cell Metab Date: 2020-07-28 Impact factor: 27.287

3. Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy.

Authors: Vlado Perkovic; Meg J Jardine; Bruce Neal; Severine Bompoint; Hiddo J L Heerspink; David M Charytan; Robert Edwards; Rajiv Agarwal; George Bakris; Scott Bull; Christopher P Cannon; George Capuano; Pei-Ling Chu; Dick de Zeeuw; Tom Greene; Adeera Levin; Carol Pollock; David C Wheeler; Yshai Yavin; Hong Zhang; Bernard Zinman; Gary Meininger; Barry M Brenner; Kenneth W Mahaffey
Journal: N Engl J Med Date: 2019-04-14 Impact factor: 91.245

Review 4. Familial renal glucosuria and SGLT2: from a mendelian trait to a therapeutic target.

Authors: René Santer; Joaquim Calado
Journal: Clin J Am Soc Nephrol Date: 2009-11-05 Impact factor: 8.237

Review 5. The tubular hypothesis of nephron filtration and diabetic kidney disease.

Authors: Volker Vallon; Scott C Thomson
Journal: Nat Rev Nephrol Date: 2020-03-09 Impact factor: 28.314

6. SGLT2 inhibitor dapagliflozin limits podocyte damage in proteinuric nondiabetic nephropathy.

Authors: Paola Cassis; Monica Locatelli; Domenico Cerullo; Daniela Corna; Simona Buelli; Cristina Zanchi; Sebastian Villa; Marina Morigi; Giuseppe Remuzzi; Ariela Benigni; Carlamaria Zoja
Journal: JCI Insight Date: 2018-08-09

7. Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes.

Authors: Kazuhiro Hasegawa; Shu Wakino; Petra Simic; Yusuke Sakamaki; Hitoshi Minakuchi; Keiko Fujimura; Kozi Hosoya; Motoaki Komatsu; Yuka Kaneko; Takeshi Kanda; Eiji Kubota; Hirobumi Tokuyama; Koichi Hayashi; Leonard Guarente; Hiroshi Itoh
Journal: Nat Med Date: 2013-10-20 Impact factor: 53.440

8. The renal hemodynamic effects of the SGLT2 inhibitor dapagliflozin are caused by post-glomerular vasodilatation rather than pre-glomerular vasoconstriction in metformin-treated patients with type 2 diabetes in the randomized, double-blind RED trial.

Authors: Erik J M van Bommel; Marcel H A Muskiet; Michaël J B van Baar; Lennart Tonneijck; Mark M Smits; Anna L Emanuel; Andrea Bozovic; A H Jan Danser; Frank Geurts; Ewout J Hoorn; Daan J Touw; Emil L Larsen; Henrik E Poulsen; Mark H H Kramer; Max Nieuwdorp; Jaap A Joles; Daniël H van Raalte
Journal: Kidney Int Date: 2019-10-10 Impact factor: 10.612