Literature DB >> 32960435

Muscle strength but not balance improves after arthroscopic biodegradable polyurethane meniscus scaffold application.

M Akkaya1, S Gursoy2, N Ozberk3, M E Simsek4, F Korkusuz5, M Bozkurt2.   

Abstract

PURPOSE: This study aimed to assess the impact of biodegradable polyurethane meniscus scaffold implantation (BPMSI) on muscle strength and balance in comparison with the healthy contralateral knee in patients with irreparable medial meniscus defect.
METHODS: This observational and prospective case-cohort study was conducted with patients who had irreparable meniscal defects and underwent arthroscopic meniscus scaffold implantation. Surgeries were carried out on the medial meniscus of 16 right and 4 left knees. Visual analog scale (VAS) was used to assess the degree of pain relief. Knee Injury and Osteoarthritis Outcome Score (KOOS) and Lysholm (LYS) score were used to evaluate the functional improvement at weeks 12, 24 and 36. Concentric and eccentric quadriceps and hamstring peak torque (PT) as well as the peak torque-to-body weight (PTB) ratio, anterior-posterior, mediolateral and overall stability indexes were assessed at the same time points.
RESULTS: Twenty male patients with a mean age and body mass index of 32.2 ± 8.8 years and 26.2 ± 4.2 kg/m2, respectively, were included in the study. The amount of pain decreased from 7.6 ± 1.5% to 2.9 ± 1.5% at postoperative week 36. Range of motion, Lysholm score and KOOS increased from 87.0ο ± 9.5ο to 115.0ο ± 15.1ο, 30.8 ± 4.3 to 81.5 ± 5.3 and 37.4 ± 5.3 to 74.1 ± 7.2, respectively. Concentric quadriceps and hamstring peak torque values and peak torque/body weight ratios were improved in the knees that received a meniscus scaffold implant. Anterior/posterior, medial/lateral, and overall stability indexes with or without biofeedback exhibited a slight improvement, which was not statistically significant.
CONCLUSION: BPMSI led to decreased pain and improved function at postoperative week 36. Although muscle strength almost returned to normal, balance parameters did not recover within 36 weeks after the procedure.
© 2020. Istituto Ortopedico Rizzoli.

Entities:  

Keywords:  Balance; Implant; Meniscus; Muscle strength; Polyurethane scaffold

Mesh:

Substances:

Year:  2020        PMID: 32960435     DOI: 10.1007/s12306-020-00681-9

Source DB:  PubMed          Journal:  Musculoskelet Surg        ISSN: 2035-5114


  35 in total

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Authors:  Cathal J Moran; Daniel P Withers; Peter R Kurzweil; Peter C Verdonk
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Review 2.  Synthetic meniscus replacement: a review.

Authors:  Anne Christiane Theodora Vrancken; Pieter Buma; Tony George van Tienen
Journal:  Int Orthop       Date:  2012-10-26       Impact factor: 3.075

Review 3.  Scaffolds for partial meniscal replacement: an updated systematic review.

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Journal:  Br Med Bull       Date:  2013-03-01       Impact factor: 4.291

4.  Meniscal scaffolds: early experience and review of the literature.

Authors:  S J Spencer; A Saithna; M R Carmont; M S Dhillon; P Thompson; T Spalding
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5.  Updates in biological therapies for knee injuries: menisci.

Authors:  Camila Cohen Kaleka; Pedro Debieux; Diego da Costa Astur; Gustavo Gonçalves Arliani; Moisés Cohen
Journal:  Curr Rev Musculoskelet Med       Date:  2014-09

6.  The safety and short-term efficacy of a novel polyurethane meniscal scaffold for the treatment of segmental medial meniscus deficiency.

Authors:  Turgay Efe; Alan Getgood; Markus D Schofer; Susanne Fuchs-Winkelmann; Dieter Mann; Jürgen R J Paletta; Thomas J Heyse
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-11-17       Impact factor: 4.342

7.  Polyurethane scaffold for the treatment of partial meniscal tears. Clinical results with a minimum two-year follow-up.

Authors:  Paolo Bulgheroni; Erica Bulgheroni; Gianmarco Regazzola; Claudio Mazzola
Journal:  Joints       Date:  2014-03-21

8.  Biodegradable polyurethane meniscal scaffold for isolated partial lesions or as combined procedure for knees with multiple comorbidities: clinical results at 2 years.

Authors:  Elizaveta Kon; Giuseppe Filardo; Stefano Zaffagnini; Alessandro Di Martino; Berardo Di Matteo; Giulio Maria Marcheggiani Muccioli; Maurizio Busacca; Maurilio Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-12-06       Impact factor: 4.342

9.  PLA-poloxamer/poloxamine copolymers for ligament tissue engineering: sound macromolecular design for degradable scaffolds and MSC differentiation.

Authors:  Adrien Leroy; Benjamin Nottelet; Claire Bony; Coline Pinese; Benoît Charlot; Xavier Garric; Danièle Noël; Jean Coudane
Journal:  Biomater Sci       Date:  2015-01-20       Impact factor: 6.843

10.  Comparative Study of Collagen versus Synthetic-Based Meniscal Scaffolds in Treating Meniscal Deficiency in Young Active Population.

Authors:  Erica Bulgheroni; Alberto Grassi; Monica Campagnolo; Paolo Bulgheroni; Abhishek Mudhigere; Alberto Gobbi
Journal:  Cartilage       Date:  2016-01       Impact factor: 4.634

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