PURPOSE: to evaluate the safety and effectiveness of the polyurethane meniscal scaffold through clinical examination, MRI and arthroscopic second look, over a minimum two-year follow-up. METHODS: between 2009 and 2011, 19 patients underwent meniscal scaffold implantation in our department (medial meniscus in 16 cases lateral meniscus in two cases, and bilateral in one case). All the patients were clinically evaluated preoperatively, and at 6, 12, and 24 months after surgery using Lysholm score, Tegner score, and VAS. Ten patients were studied with MRI, and nine patients were evaluated arthroscopically. RESULTS: no adverse reactions to the implant were observed. The clinical scores showed a significant improvement at 6 months and increased progressively over time. On MRI studies, the implants showed a clear hyperintense signal, sometimes irregular, and the chondral surface was preserved in all cases. At arthroscopic second look in the first months after surgery, the scaffold size was unchanged and the scaffold appeared light yellowish in color and well integrated into the surrounding tissues. At arthroscopic second look at 12 and 24 months the scaffold was found to have an irregular morphology and to be slightly reduced in size. CONCLUSIONS: polyurethane meniscal scaffold is a good alternative to a collagen scaffold, but a longer follow-up is needed to evaluate the scaffold degradation and chondral coverage. LEVEL OF EVIDENCE: level IV, therapeutic case series.
PURPOSE: to evaluate the safety and effectiveness of the polyurethane meniscal scaffold through clinical examination, MRI and arthroscopic second look, over a minimum two-year follow-up. METHODS: between 2009 and 2011, 19 patients underwent meniscal scaffold implantation in our department (medial meniscus in 16 cases lateral meniscus in two cases, and bilateral in one case). All the patients were clinically evaluated preoperatively, and at 6, 12, and 24 months after surgery using Lysholm score, Tegner score, and VAS. Ten patients were studied with MRI, and nine patients were evaluated arthroscopically. RESULTS: no adverse reactions to the implant were observed. The clinical scores showed a significant improvement at 6 months and increased progressively over time. On MRI studies, the implants showed a clear hyperintense signal, sometimes irregular, and the chondral surface was preserved in all cases. At arthroscopic second look in the first months after surgery, the scaffold size was unchanged and the scaffold appeared light yellowish in color and well integrated into the surrounding tissues. At arthroscopic second look at 12 and 24 months the scaffold was found to have an irregular morphology and to be slightly reduced in size. CONCLUSIONS:polyurethane meniscal scaffold is a good alternative to a collagen scaffold, but a longer follow-up is needed to evaluate the scaffold degradation and chondral coverage. LEVEL OF EVIDENCE: level IV, therapeutic case series.
Authors: Peter Verdonk; Philippe Beaufils; Johan Bellemans; Patrick Djian; Eva-Lisa Heinrichs; Wouter Huysse; Heinz Laprell; Rainer Siebold; René Verdonk Journal: Am J Sports Med Date: 2012-02-09 Impact factor: 6.202
Authors: Peter C M Verdonk; Koenraad L Verstraete; Karl F Almqvist; Kristof De Cuyper; Eric M Veys; Gust Verbruggen; René Verdonk Journal: Knee Surg Sports Traumatol Arthrosc Date: 2006-02-07 Impact factor: 4.342
Authors: G Filardo; E Kon; F Perdisa; A Sessa; A Di Martino; M Busacca; S Zaffagnini; M Marcacci Journal: Knee Surg Sports Traumatol Arthrosc Date: 2016-07-09 Impact factor: 4.342
Authors: Andrzej Brzezinski; Salim A Ghodbane; Jay M Patel; Barbara A Perry; Charles J Gatt; Michael G Dunn Journal: Tissue Eng Part C Methods Date: 2017-09-29 Impact factor: 3.056
Authors: Darby A Houck; Matthew J Kraeutler; John W Belk; Eric C McCarty; Jonathan T Bravman Journal: Knee Surg Sports Traumatol Arthrosc Date: 2018-01-16 Impact factor: 4.342
Authors: Marc Tey-Pons; Bruno Capurro; Raúl Torres-Eguia; Fernando Marqués-López; Alfonso Leon-García; Oliver Marín-Peña Journal: J Hip Preserv Surg Date: 2021-06-23