Literature DB >> 32944617

Neural reprogramming via microRNAs: the new kid on the p53-deficient block.

Deborah A Silverman1, George A Calin2, Jeffrey N Myers3, Moran Amit3.   

Abstract

We recently reported a novel role for nerve-cancer crosstalk, demonstrating that tumor protein p53 (TP53) deficiency in head and neck squamous cell carcinoma leads to a decrease in miR-34a in tumor-shed vesicles. This directed sensory nerve reprogramming in the tumor microenvironment which enhanced tumor growth.
© 2020 Taylor & Francis Group, LLC.

Entities:  

Keywords:  TP53; adrenergic signaling; head and neck cancer; miR-34a; microRNA; neural reprogramming; p53; tumor microenvironment

Year:  2020        PMID： 32944617      PMCID： PMC7469510          DOI： 10.1080/23723556.2020.1756723

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  7 in total

1.  A microRNA array reveals extensive regulation of microRNAs during brain development.

Authors:  Anna M Krichevsky; Kevin S King; Christine P Donahue; Konstantin Khrapko; Kenneth S Kosik
Journal:  RNA       Date:  2003-10       Impact factor: 4.942

2.  Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia.

Authors:  Muller Fabbri; Arianna Bottoni; Masayoshi Shimizu; Riccardo Spizzo; Milena S Nicoloso; Simona Rossi; Elisa Barbarotto; Amelia Cimmino; Brett Adair; Sylwia E Wojcik; Nicola Valeri; Federica Calore; Deepa Sampath; Francesca Fanini; Ivan Vannini; Gerardo Musuraca; Marie Dell'Aquila; Hansjuerg Alder; Ramana V Davuluri; Laura Z Rassenti; Massimo Negrini; Tatsuya Nakamura; Dino Amadori; Neil E Kay; Kanti R Rai; Michael J Keating; Thomas J Kipps; George A Calin; Carlo M Croce
Journal:  JAMA       Date:  2011-01-05       Impact factor: 56.272

3.  p53 functional deficiency in human colon cancer cells promotes fibroblast-mediated angiogenesis and tumor growth.

Authors:  Yoshito Hayashi; Masahiko Tsujii; Takahiro Kodama; Tomofumi Akasaka; Jumpei Kondo; Hayato Hikita; Takuya Inoue; Yoshiki Tsujii; Akira Maekawa; Shunsuke Yoshii; Shinichiro Shinzaki; Kenji Watabe; Yasuhiko Tomita; Masahiro Inoue; Tomohide Tatsumi; Hideki Iijima; Tetsuo Takehara
Journal:  Carcinogenesis       Date:  2016-08-12       Impact factor: 4.944

4.  Autonomic nerve development contributes to prostate cancer progression.

Authors:  Claire Magnon; Simon J Hall; Juan Lin; Xiaonan Xue; Leah Gerber; Stephen J Freedland; Paul S Frenette
Journal:  Science       Date:  2013-07-12       Impact factor: 47.728

5.  Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis.

Authors:  Tsung-Cheng Chang; Erik A Wentzel; Oliver A Kent; Kalyani Ramachandran; Michael Mullendore; Kwang Hyuck Lee; Georg Feldmann; Munekazu Yamakuchi; Marcella Ferlito; Charles J Lowenstein; Dan E Arking; Michael A Beer; Anirban Maitra; Joshua T Mendell
Journal:  Mol Cell       Date:  2007-05-31       Impact factor: 17.970

6.  Non-cell-autonomous tumor suppression by p53.

Authors:  Amaia Lujambio; Leila Akkari; Janelle Simon; Danielle Grace; Darjus F Tschaharganeh; Jessica E Bolden; Zhen Zhao; Vishal Thapar; Johanna A Joyce; Valery Krizhanovsky; Scott W Lowe
Journal:  Cell       Date:  2013-04-04       Impact factor: 41.582

7.  Loss of p53 drives neuron reprogramming in head and neck cancer.

Authors:  Moran Amit; Hideaki Takahashi; Mihnea Paul Dragomir; Antje Lindemann; Frederico O Gleber-Netto; Curtis R Pickering; Simone Anfossi; Abdullah A Osman; Yu Cai; Rong Wang; Erik Knutsen; Masayoshi Shimizu; Cristina Ivan; Xiayu Rao; Jing Wang; Deborah A Silverman; Samantha Tam; Mei Zhao; Carlos Caulin; Assaf Zinger; Ennio Tasciotti; Patrick M Dougherty; Adel El-Naggar; George A Calin; Jeffrey N Myers
Journal:  Nature       Date:  2020-02-12       Impact factor: 69.504
  7 in total

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