Adalberto Miranda-Filho1, Freddie Bray2, Hadrien Charvat2, Swaminathan Rajaraman3, Isabelle Soerjomataram2. 1. Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France. Electronic address: mirandaa@fellows.iarc.fr. 2. Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France. 3. Department of Epidemiology, Biostatistics and Cancer Registry, Cancer Institute (WIA), Chennai, India.
Abstract
PURPOSE: This study addresses the need for a global cancer patient-based standard population that adjusts for the expected age structure of different cancers, thus aiding the comparison of survival estimates worldwide. METHODS: Counts of age-specific incidence for 36 cancer sites in 185 countries for the year 2018 were extracted from IARC's GLOBOCAN database of national estimates. We used a multinomial mixture regression to identify clusters of cancer sites with similar age-specific profiles. RESULTS: An updated standard entitled the World Cancer Patient Population (WCPP) is presented, derived from the current estimated global numbers of cancer patients that comprises three sets of age-specific weights. Around two-thirds of cancer sites were described by a unique standard, representing the majority of epithelial cancers more often diagnosed at older age groups. The two other standards represent a number of non-epithelial cancer types, and cancers common at younger and older age groups, respectively. CONCLUSION: The WCPP proposed here provides a contemporary and global means to estimate age-standardised survival for international benchmarking purposes.
PURPOSE: This study addresses the need for a global cancerpatient-based standard population that adjusts for the expected age structure of different cancers, thus aiding the comparison of survival estimates worldwide. METHODS: Counts of age-specific incidence for 36 cancer sites in 185 countries for the year 2018 were extracted from IARC's GLOBOCAN database of national estimates. We used a multinomial mixture regression to identify clusters of cancer sites with similar age-specific profiles. RESULTS: An updated standard entitled the World CancerPatient Population (WCPP) is presented, derived from the current estimated global numbers of cancerpatients that comprises three sets of age-specific weights. Around two-thirds of cancer sites were described by a unique standard, representing the majority of epithelial cancers more often diagnosed at older age groups. The two other standards represent a number of non-epithelial cancer types, and cancers common at younger and older age groups, respectively. CONCLUSION: The WCPP proposed here provides a contemporary and global means to estimate age-standardised survival for international benchmarking purposes.
Authors: Jacques Ferlay; Isabelle Soerjomataram; Rajesh Dikshit; Sultan Eser; Colin Mathers; Marise Rebelo; Donald Maxwell Parkin; David Forman; Freddie Bray Journal: Int J Cancer Date: 2014-10-09 Impact factor: 7.396
Authors: Freddie Bray; Jacques Ferlay; Isabelle Soerjomataram; Rebecca L Siegel; Lindsey A Torre; Ahmedin Jemal Journal: CA Cancer J Clin Date: 2018-09-12 Impact factor: 508.702
Authors: J Ferlay; M Colombet; I Soerjomataram; C Mathers; D M Parkin; M Piñeros; A Znaor; F Bray Journal: Int J Cancer Date: 2018-12-06 Impact factor: 7.396