Literature DB >> 32941074

A novel microRNA-based signature predicts prognosis among nasopharyngeal cancer patients.

Tianyu Wang1, Jian Wu1, Yun Wu2, Yin Cheng1, Yue Deng1, Jianchun Liao1, Huanhai Liu1, Hu Peng1.   

Abstract

IMPACT STATEMENT: Nasopharyngeal cancer is one of the most common malignant tumors in the head and neck. Identification of promising miRNA biomarkers might benefit a lot to the detection of nasopharyngeal carcinoma. A three-miRNA signature (has-miR-142-3p, has-miR-29c, and has-miR-30e) was obviously associated with the overall survival of nasopharyngeal carcinoma patients. The model has better clinical independence and has better clinical prediction effect when combined with clinical characteristics. Our results revealed that a three-miRNA signature was a potential novel prognostic biomarker for nasopharyngeal carcinoma.

Entities:  

Keywords:  Gene Expression Omnibus; Nasopharyngeal cancer; area under the curve; miRNA signature

Mesh:

Substances:

Year:  2020        PMID: 32941074      PMCID: PMC7797999          DOI: 10.1177/1535370220958680

Source DB:  PubMed          Journal:  Exp Biol Med (Maywood)        ISSN: 1535-3699


  33 in total

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8.  EBV-miR-BART8-3p induces epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma cells through activating NF-κB and Erk1/2 pathways.

Authors:  Cheng Lin; Jingfeng Zong; Wansong Lin; Minghui Wang; Yuanji Xu; Rui Zhou; Shaojun Lin; Qiaojuan Guo; Honglin Chen; Yunbin Ye; Bin Zhang; Jianji Pan
Journal:  J Exp Clin Cancer Res       Date:  2018-11-26

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Authors:  Yingqin Li; Qingmei He; Xin Wen; Xiaohong Hong; Xiaojing Yang; Xinran Tang; Panpan Zhang; Yuan Lei; Ying Sun; Jian Zhang; Yaqin Wang; Jun Ma; Na Liu
Journal:  Cell Death Differ       Date:  2018-10-23       Impact factor: 15.828

10.  Two miRNA prognostic signatures of head and neck squamous cell carcinoma: A bioinformatic analysis based on the TCGA dataset.

Authors:  Chaoying Wu; Lingxia Tong; Chaoqun Wu; Dong Chen; Jianguo Chen; Qianyun Li; Fang Jia; Zirui Huang
Journal:  Cancer Med       Date:  2020-02-17       Impact factor: 4.452

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  4 in total

1.  A novel three-microRNA signature for predicting survival in patients with nasopharyngeal carcinoma.

Authors:  Shan-Qiang Zhang; Jun Liu; Hai-Bin Chen; Wen-Jie Dai; Li-Qing Zhou; Chong-Wei Xie; Ji-Cheng Li
Journal:  J Dent Sci       Date:  2021-09-08       Impact factor: 2.080

2.  A Five-MicroRNA Signature Predicts the Prognosis in Nasopharyngeal Carcinoma.

Authors:  Shixiong Wu; Cen Zhang; Jing Xie; Shuang Li; Shuo Huang
Journal:  Front Oncol       Date:  2021-09-09       Impact factor: 6.244

Review 3.  Promising Biomarkers in Head and Neck Cancer: The Most Clinically Important miRNAs.

Authors:  Arsinoe C Thomaidou; Panagiota Batsaki; Maria Adamaki; Maria Goulielmaki; Constantin N Baxevanis; Vassilis Zoumpourlis; Sotirios P Fortis
Journal:  Int J Mol Sci       Date:  2022-07-26       Impact factor: 6.208

4.  miR-137 Inhibition of the Invasion, Metastasis, and Epithelial-Mesenchymal Transition of Nasopharyngeal Cancer by Regulating KDM1A.

Authors:  Han-Qiang Lu; Run-Kun Wang; Hui-Rong Wang; Guang-Quan Zhou; Yan-Shu Zhang
Journal:  J Oncol       Date:  2021-12-17       Impact factor: 4.375

  4 in total

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