| Literature DB >> 17506695 |
Natascha Bushati1, Stephen M Cohen.
Abstract
microRNAs (miRNAs) are small noncoding RNAs that play important roles in posttranscriptional gene regulation. In animal cells, miRNAs regulate their targets by translational inhibition and mRNA destabilization. Here, we review recent work in animal models that provide insight into the diverse roles of miRNAs in vivo.Mesh:
Substances:
Year: 2007 PMID: 17506695 DOI: 10.1146/annurev.cellbio.23.090506.123406
Source DB: PubMed Journal: Annu Rev Cell Dev Biol ISSN: 1081-0706 Impact factor: 13.827