| Literature DB >> 3292345 |
P R McNally1, C L Maydonovitch, R K Wong.
Abstract
The effect of simethicone in improving visibility during colonoscopy was randomly studied in 97 patients receiving either simethicone (N = 49) or placebo (N = 48) in a colon lavage solution. Visibility was assessed by the amount of bubbles and the degree of haziness noted during colonoscopy. The degree of bubbles was scored on a scale of 0 to 3, and haziness was scored on a scale of 0 to 2. Patients receiving simethicone had significantly less bubbles (p less than 0.001) and less haziness (p less than 0.01) in the colon when compared to placebo-treated patients. These data indicate that the addition of simethicone to the colonic lavage solution results in improved colonic visibility and may result in technically easier and more accurate colonoscopy.Entities:
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Year: 1988 PMID： 3292345 DOI： 10.1016/s0016-5107(88)71324-3
Source DB: PubMed Journal: Gastrointest Endosc ISSN： 0016-5107 Impact factor: 9.427