Literature DB >> 32908070

Laboratory diagnosis of COVID-19 in Africa: availability, challenges and implications.

Elijah Kolawole Oladipo1,2, Ayodeji Folorunsho Ajayi3, Aduragbemi Noah Odeyemi3, Olawumi Elizabeth Akindiya4, Emmanuel Tayo Adebayo3, Ayomide Samuel Oguntomi2, Moyosoluwa Precious Oyewole5, Esther Moradeyo Jimah2,6, Abayomi Adio Oladipo7, Olumuyiwa Elijah Ariyo8, Bukola Bisola Oladipo9, Julius Kola Oloke10.   

Abstract

The COVID-19 infection has been a matter of urgency to tackle around the world today, there exist 200 countries around the world and 54 countries in Africa that the COVID-19 infection cases have been confirmed. This situation prompted us to look into the challenges African laboratories are facing in the diagnosis of novel COVID-19 infection. A limited supply of essential laboratory equipment and test kits are some of the challenges faced in combatting the novel virus in Africa. Also, there is inadequate skilled personnel, which might pose a significant danger in case there is a surge in COVID-19 infection cases. The choice of diagnostic method in Africa is limited as there are only two available diagnostic methods being used out of the six methods used globally, thereby reducing the opportunity of supplementary diagnosis, which will further lead to inappropriate diagnosis and affect the accuracy of diagnostic reports. Furthermore, challenges like inadequate power supply, the method used in sample collection, storage and transportation of specimens are also significant as they also pose their respective implication. From the observations, there is an urgent need for more investment into the laboratories for proper, timely, and accurate diagnosis of COVID-19.

Entities:  

Keywords:  Africa; COVID-19; challenges; implications; laboratory diagnosis

Mesh:

Year:  2020        PMID: 32908070     DOI: 10.5582/ddt.2020.03067

Source DB:  PubMed          Journal:  Drug Discov Ther        ISSN: 1881-7831


  7 in total

1.  SARS-CoV-2 Antibody Prevalence and Population-Based Death Rates, Greater Omdurman, Sudan.

Authors:  Wendelin Moser; Mohammed Ahmed Hassan Fahal; Elamin Abualas; Shahinaz Bedri; Mahgoub Taj Elsir; Mona Fateh El Rahman Omer Mohamed; Abdelhalim Babiker Mahmoud; Amna Ismail Ibrahim Ahmad; Mohammed A Adam; Sami Altalib; Ola Adil DafaAllah; Salahaldin Abdallah Hmed; Andrew S Azman; Iza Ciglenecki; Etienne Gignoux; Alan González; Christine Mwongera; Manuel Albela Miranda
Journal:  Emerg Infect Dis       Date:  2022-05       Impact factor: 6.883

Review 2.  COVID-19 preparedness: capacity to manufacture vaccines, therapeutics and diagnostics in sub-Saharan Africa.

Authors:  Bisi Bright; Chinedum Peace Babalola; Nadia Adjoa Sam-Agudu; Augustine Anayochukwu Onyeaghala; Adebola Olatunji; Ufuoma Aduh; Patrick O Sobande; Trevor A Crowell; Yenew Kebede Tebeje; Sunny Phillip; Nicaise Ndembi; Morenike Oluwatoyin Folayan
Journal:  Global Health       Date:  2021-03-03       Impact factor: 4.185

3.  COVID-19 in Oromia Region of Ethiopia: a review of the first 6 months' surveillance data.

Authors:  Esayas Kebede Gudina; Dabesa Gobena; Tessema Debela; Daniel Yilma; Tsinuel Girma; Zeleke Mekonnen; Mirkuzie Woldie; Dereje Abdena; Gemechu Shume; Birhanu Kenate; Meles Lemi; Dereje Diriba; Tizta Tilahun Degfie
Journal:  BMJ Open       Date:  2021-03-29       Impact factor: 2.692

4.  Designing a conserved peptide-based subunit vaccine against SARS-CoV-2 using immunoinformatics approach.

Authors:  Elijah Kolawole Oladipo; Ayodeji Folorunsho Ajayi; Olugbenga Samson Onile; Olumuyiwa Elijah Ariyo; Esther Moradeyo Jimah; Louis Odinakaose Ezediuno; Oluwadunsin Iyanuoluwa Adebayo; Emmanuel Tayo Adebayo; Aduragbemi Noah Odeyemi; Marvellous Oluwaseun Oyeleke; Moyosoluwa Precious Oyewole; Ayomide Samuel Oguntomi; Olawumi Elizabeth Akindiya; Victoria Oyetayo Aremu; Dorcas Olubunmi Aboderin; Julius Kola Oloke
Journal:  In Silico Pharmacol       Date:  2021-01-06

5.  COVID-19 Testing Experience in a Resource-Limited Setting: The Use of Existing Facilities in Public Health Emergency Management.

Authors:  Nega Assefa; Jemal Yousuf Hassen; Desalegn Admassu; Mussie Brhane; Mersen Deressa; Dadi Marami; Zelalem Teklemariam; Yadeta Dessie; Joseph Oundo
Journal:  Front Public Health       Date:  2021-06-14

6.  Humanitarian Surgical Missions in Times of COVID-19: Recommendations to Safely Return to a Sub-Saharan Africa Low-Resource Setting.

Authors:  Víctor Lopez-Lopez; Ana Morales; Elisa García-Vazquez; Miguel González; Quiteria Hernandez; Alberto Baroja-Mazo; Dolores Palazon; Jose A Tortosa; Maria A Rodriguez; Nuria M Torregrosa; Winnie Kanyi; J K Ndungu; José Gil Martinez; José M Rodriguez
Journal:  World J Surg       Date:  2021-02-20       Impact factor: 3.282

7.  fM-aM Detection of the SARS-CoV-2 Antigen by Advanced Lateral Flow Immunoassay Based on Gold Nanospheres.

Authors:  Yilin Liu; Li Zhan; Jesse W Shen; Bàrbara Baro; Andrea Alemany; James Sackrison; Oriol Mitjà; John C Bischof
Journal:  ACS Appl Nano Mater       Date:  2021-12-14
  7 in total

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