| Literature DB >> 32890064 |
Ayham Alkhachroum1,2, Caroline A Der-Nigoghossian1, Clio Rubinos1, Jan Claassen1.
Abstract
Status epilepticus (SE) is a neurologic emergency with high morbidity and mortality. The assessment of a patient's prognosis is crucial in making treatment decisions. In this review, we discuss various markers that have been used to prognosticate SE in terms of recurrence, mortality, and functional outcome. These markers include demographic, clinical, electrophysiological, biochemical, and structural data. The heterogeneity of SE etiology and semiology renders development of prognostic markers challenging. Currently, prognostication in SE is limited to a few clinical scores. Future research should integrate clinical, genetic and epigenetic, metabolic, inflammatory, and structural biomarkers into prognostication models to approach "personalized medicine" in prognostication of outcomes after SE.Entities:
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Year: 2020 PMID: 32890064 PMCID: PMC7864547 DOI: 10.1097/WNP.0000000000000761
Source DB: PubMed Journal: J Clin Neurophysiol ISSN: 0736-0258 Impact factor: 2.590