Literature DB >> 32890064

Markers in Status Epilepticus Prognosis.

Ayham Alkhachroum1,2, Caroline A Der-Nigoghossian1, Clio Rubinos1, Jan Claassen1.   

Abstract

Status epilepticus (SE) is a neurologic emergency with high morbidity and mortality. The assessment of a patient's prognosis is crucial in making treatment decisions. In this review, we discuss various markers that have been used to prognosticate SE in terms of recurrence, mortality, and functional outcome. These markers include demographic, clinical, electrophysiological, biochemical, and structural data. The heterogeneity of SE etiology and semiology renders development of prognostic markers challenging. Currently, prognostication in SE is limited to a few clinical scores. Future research should integrate clinical, genetic and epigenetic, metabolic, inflammatory, and structural biomarkers into prognostication models to approach "personalized medicine" in prognostication of outcomes after SE.

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Year:  2020        PMID: 32890064      PMCID: PMC7864547          DOI: 10.1097/WNP.0000000000000761

Source DB:  PubMed          Journal:  J Clin Neurophysiol        ISSN: 0736-0258            Impact factor:   2.590


  144 in total

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2.  Clinical outcomes following prolonged refractory status epilepticus (PRSE).

Authors:  R D Kilbride; A S Reynolds; J P Szaflarski; L J Hirsch
Journal:  Neurocrit Care       Date:  2013-06       Impact factor: 3.210

3.  Does status epilepticus in children cause developmental deterioration and exacerbation of epilepsy?

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Authors:  M Holtkamp; J Othman; K Buchheim; H Meierkord
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5.  Association of seizure duration and outcome in refractory status epilepticus.

Authors:  Dominik Madžar; Anna Geyer; Ruben U Knappe; Stephanie Gollwitzer; Joji B Kuramatsu; Stefan T Gerner; Hajo M Hamer; Hagen B Huttner
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Review 6.  Are you in or out? Leukocyte, ion, and neurotransmitter permeability across the epileptic blood-brain barrier.

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Journal:  Epilepsia       Date:  2012-06       Impact factor: 5.864

Review 7.  Glia and epilepsy: excitability and inflammation.

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9.  Generalized periodic discharges in the critically ill: a case-control study of 200 patients.

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10.  Nonconvulsive seizures in subarachnoid hemorrhage link inflammation and outcome.

Authors:  Jan Claassen; David Albers; J Michael Schmidt; Gian Marco De Marchis; Deborah Pugin; Christina Maria Falo; Stephan A Mayer; Serge Cremers; Sachin Agarwal; Mitchell S V Elkind; E Sander Connolly; Vanja Dukic; George Hripcsak; Neeraj Badjatia
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2.  Quantitative EEG-Based Seizure Estimation in Super-Refractory Status Epilepticus.

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Journal:  Neurocrit Care       Date:  2021-11-17       Impact factor: 3.210

3.  Clinico-biological markers for the prognosis of status epilepticus in adults.

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4.  Factors affecting prognosis of status epilepticus among patients presenting to a tertiary care hospital.

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