Literature DB >> 32888003

Severe Acute Respiratory Syndrome Coronavirus 2 RNA in Plasma Is Associated With Intensive Care Unit Admission and Mortality in Patients Hospitalized With Coronavirus Disease 2019.

Christian Prebensen1,2, Peder L Myhre2,3, Christine Jonassen4, Anbjørg Rangberg4, Anita Blomfeldt5, My Svensson6, Torbjørn Omland2,3, Jan-Erik Berdal1,2.   

Abstract

The clinical significance of severe acute respiratory syndrome coronavirus 2 RNA in the circulation is unknown. In this prospective cohort study, we detected viral RNA in the plasma of 58 of 123 (47%) patients hospitalized with coronavirus disease 2019. RNA was detected more frequently, and levels were higher, in patients who were admitted to the intensive care unit and/or died.
© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  COVID-19; RNAemia; SARS-CoV-2; antibodies; viral load

Year:  2021        PMID： 32888003      PMCID： PMC7499533          DOI： 10.1093/cid/ciaa1338

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  37 in total

1.  SARS-CoV-2 Viral Load in the Pulmonary Compartment of Critically Ill COVID-19 Patients Correlates with Viral Serum Load and Fatal Outcomes.

Authors:  Mario Ynga-Durand; Henrike Maaß; Marko Milošević; Fran Krstanović; Marina Pribanić Matešić; Stipan Jonjić; Alen Protić; Ilija Brizić; Alan Šustić; Luka Čičin-Šain
Journal:  Viruses       Date:  2022-06-14       Impact factor: 5.818

2.  Investigation of Extracellular Vesicles From SARS-CoV-2 Infected Specimens: A Safety Perspective.

Authors:  Yury O Nunez Lopez; Anna Casu; Richard E Pratley
Journal:  Front Immunol       Date:  2021-04-22       Impact factor: 7.561

3.  Seasonal Stability of SARS-CoV-2 in Biological Fluids.

Authors:  Taeyong Kwon; Natasha N Gaudreault; Juergen A Richt
Journal:  Pathogens       Date:  2021-04-30

4.  SARS-CoV-2 RNAemia Predicts Clinical Deterioration and Extrapulmonary Complications from COVID-19.

Authors:  Nikhil Ram-Mohan; David Kim; Elizabeth J Zudock; Marjan M Hashemi; Kristel C Tjandra; Angela J Rogers; Catherine A Blish; Kari C Nadeau; Jennifer A Newberry; James V Quinn; Ruth O'Hara; Euan Ashley; Hien Nguyen; Lingxia Jiang; Paul Hung; Andra L Blomkalns; Samuel Yang
Journal:  Clin Infect Dis       Date:  2022-01-29       Impact factor: 9.079

5.  Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns.

Authors:  E E Christensen; M J Jørgensen; K G Nore; T B Dahl; K Yang; T Ranheim; C Huse; A Lind; S Nur; B Stiksrud; S Jenum; K Tonby; J C Holter; A R Holten; B Halvorsen; A M Dyrhol-Riise
Journal:  J Intern Med       Date:  2021-06-03       Impact factor: 13.068

6.  Feasibility of convalescent plasma therapy in severe COVID-19 patients with persistent SARS-CoV-2 viremia.

Authors:  Fabrice Camou; Claire Tinevez; Mathilde Beguet-Yachine; Pantxika Bellecave; Diana Ratiarison; Camille Tumiotto; Xavier Lafarge; Olivier Guisset; Gaëlle Mourissoux; Marie-Edith Lafon; Fabrice Bonnet; Nahéma Issa
Journal:  J Med Virol       Date:  2021-05-03       Impact factor: 20.693

7.  Protective effects of eosinophils against COVID-19: More than an ACE(2) in the hole?

Authors:  Matthew G Drake; Allison D Fryer; David B Jacoby
Journal:  J Allergy Clin Immunol Pract       Date:  2021-06

8.  SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes.

Authors:  Yijia Li; Alexis M Schneider; Arnav Mehta; Moshe Sade-Feldman; Kyle R Kays; Matteo Gentili; Nicole C Charland; Anna Lk Gonye; Irena Gushterova; Hargun K Khanna; Thomas J LaSalle; Kendall M Lavin-Parsons; Brendan M Lilley; Carl L Lodenstein; Kasidet Manakongtreecheep; Justin D Margolin; Brenna N McKaig; Blair A Parry; Maricarmen Rojas-Lopez; Brian C Russo; Nihaarika Sharma; Jessica Tantivit; Molly F Thomas; James Regan; James P Flynn; Alexandra-Chloé Villani; Nir Hacohen; Marcia B Goldberg; Michael R Filbin; Jonathan Z Li
Journal:  J Clin Invest       Date:  2021-07-01       Impact factor: 14.808

Review 9.  Pathophysiology of infection with SARS-CoV-2-What is known and what remains a mystery.

Authors:  Siddharth Sridhar; John Nicholls
Journal:  Respirology       Date:  2021-05-26       Impact factor: 6.175

10.  Severe Acute Respiratory Syndrome Coronavirus 2 Viremia Is Associated With Coronavirus Disease 2019 Severity and Predicts Clinical Outcomes.

Authors:  Jana L Jacobs; William Bain; Asma Naqvi; Brittany Staines; Priscila M S Castanha; Haopu Yang; Valerie F Boltz; Simon Barratt-Boyes; Ernesto T A Marques; Stephanie L Mitchell; Barbara Methé; Tolani F Olonisakin; Ghady Haidar; Thomas W Burke; Elizabeth Petzold; Thomas Denny; Chris W Woods; Bryan J McVerry; Janet S Lee; Simon C Watkins; Claudette M St Croix; Alison Morris; Mary F Kearney; Mark S Ladinsky; Pamela J Bjorkman; Georgios D Kitsios; John W Mellors
Journal:  Clin Infect Dis       Date:  2022-05-03       Impact factor: 20.999
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