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Literature DB >> 32882476

Immunomodulatory activities of polysaccharides from Ganoderma on immune effector cells.

Abstract

Polysaccharides are the most abundant bioactive compounds in Ganoderma and have been widely used as dietary supplements in traditional Chinese medicine for thousands of years. Polysaccharides from Ganoderma exhibit unique biological properties, including anti-tumor, anti-inflammatory, and immunomodulatory activities. Herein, the sources and structures of polysaccharides from Ganoderma were presented. This work also reviews the immunomodulatory activities and possible mechanisms of polysaccharides from Ganoderma on different immune effector cells, including lymphocytes and myeloid cells. As an available adjunctive remedy, polysaccharides from Ganoderma can potentially be applied for the modulation of the host immune system, namely the innate immunity, the cellular immunity, and the humoral immunity.

Entities: Chemical Disease

Keywords: Adjunctive remedy; Ganoderma; Immune cells; Immunomodulation; Polysaccharides

Mesh：

Substances：

Year: 2020 PMID： 32882476 DOI： 10.1016/j.foodchem.2020.127933

Source DB: PubMed Journal: Food Chem ISSN： 0308-8146 Impact factor: 7.514

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Cited

25 in total

Review 1. Research Progress on the Anticancer Activities and Mechanisms of Polysaccharides From Ganoderma.

Authors: Man Wang; Fei Yu
Journal: Front Pharmacol Date: 2022-07-05 Impact factor: 5.988

2. Root-Knot Disease Suppression in Eggplant Based on Three Growth Ages of Ganoderma lucidum.

Authors: Saba Fatima; Faryad Khan; Mohd Asif; Saqer S Alotaibi; Khushbu Islam; Mohammad Shariq; Arshad Khan; Mohd Ikram; Faheem Ahmad; Tabreiz Ahmad Khan; Rampratap Meena; Mansoor Ahmad Siddiqui
Journal: Microorganisms Date: 2022-05-23

3. Ganoderma formosanum Exopolysaccharides Inhibit Tumor Growth via Immunomodulation.

Authors: Hsing-Chun Kuo; Yen-Wenn Liu; Chi-Chin Lum; Kai-Di Hsu; Shin-Ping Lin; Chang-Wei Hsieh; Hui-Wen Lin; Tze-Ying Lu; Kuan-Chen Cheng
Journal: Int J Mol Sci Date: 2021-10-19 Impact factor: 5.923

4. Exploring the Protective and Reparative Mechanisms of G. lucidum Polysaccharides Against H₂O₂-Induced Oxidative Stress in Human Skin Fibroblasts.

Authors: Xiuqin Shi; Wenjing Cheng; Qian Wang; Jiachan Zhang; Changtao Wang; Meng Li; Dan Zhao; Dongdong Wang; Quan An
Journal: Clin Cosmet Investig Dermatol Date: 2021-10-14

Review 5. Polysaccharide Regulation of Intestinal Flora: A Viable Approach to Maintaining Normal Cognitive Performance and Treating Depression.

Authors: Xinzhou Wang; Lu Cheng; Yanan Liu; Ruilin Zhang; Zufang Wu; Peifang Weng; Peng Zhang; Xin Zhang
Journal: Front Microbiol Date: 2022-03-11 Impact factor: 5.640

Immunomodulatory activities of polysaccharides from Ganoderma on immune effector cells.

Review 1. Research Progress on the Anticancer Activities and Mechanisms of Polysaccharides From Ganoderma.

2. Root-Knot Disease Suppression in Eggplant Based on Three Growth Ages of Ganoderma lucidum.

3. Ganoderma formosanum Exopolysaccharides Inhibit Tumor Growth via Immunomodulation.

4. Exploring the Protective and Reparative Mechanisms of G. lucidum Polysaccharides Against H₂O₂-Induced Oxidative Stress in Human Skin Fibroblasts.

Review 5. Polysaccharide Regulation of Intestinal Flora: A Viable Approach to Maintaining Normal Cognitive Performance and Treating Depression.

Review 6. Polysaccharides as Potential Anti-tumor Biomacromolecules -A Review.

7. Preparation, Antioxidant and Immunoregulatory Activities of a Macromolecular Glycoprotein from Salvia miltiorrhiza.

Review 8. Effects of Medicinal Fungi-Derived β-Glucan on Tumor Progression.

9. Polysaccharides from Basidiocarps of the Polypore Fungus Ganoderma resinaceum: Isolation and Structure.

10. Identification of 20(S)-Ginsenoside Rh2 as a Potential EGFR Tyrosine Kinase Inhibitor.

Immunomodulatory activities of polysaccharides from Ganoderma on immune effector cells.

Review 1. Research Progress on the Anticancer Activities and Mechanisms of Polysaccharides From Ganoderma.

2. Root-Knot Disease Suppression in Eggplant Based on Three Growth Ages of Ganoderma lucidum.

3. Ganoderma formosanum Exopolysaccharides Inhibit Tumor Growth via Immunomodulation.

4. Exploring the Protective and Reparative Mechanisms of G. lucidum Polysaccharides Against H2O2-Induced Oxidative Stress in Human Skin Fibroblasts.

Review 5. Polysaccharide Regulation of Intestinal Flora: A Viable Approach to Maintaining Normal Cognitive Performance and Treating Depression.

Review 6. Polysaccharides as Potential Anti-tumor Biomacromolecules -A Review.

7. Preparation, Antioxidant and Immunoregulatory Activities of a Macromolecular Glycoprotein from Salvia miltiorrhiza.

Review 8. Effects of Medicinal Fungi-Derived β-Glucan on Tumor Progression.

9. Polysaccharides from Basidiocarps of the Polypore Fungus Ganoderma resinaceum: Isolation and Structure.

10. Identification of 20(S)-Ginsenoside Rh2 as a Potential EGFR Tyrosine Kinase Inhibitor.

4. Exploring the Protective and Reparative Mechanisms of G. lucidum Polysaccharides Against H₂O₂-Induced Oxidative Stress in Human Skin Fibroblasts.