Literature DB >> 32879725

Masquerading in the midgut: a rare diagnosis in a patient with recurrent abdominal pain.

Philip J Smith1, Trusha Patel1, Nicholas Reading2, Konstantinos Giaslakiotis3, Sami Hoque1.   

Abstract

A 38-year-old woman who had been previously diagnosed with irritable bowel syndrome was seen in the outpatient clinic with a 2-year history of intermittent cramp-like abdominal pain which was often followed by watery diarrhoea. She had presented several times previously to the emergency department with episodes of severe pain and collapse although on arrival examination findings were mostly unremarkable other than some mild lower abdominal tenderness. On each occasion, the symptoms resolved spontaneously with conservative management. She had been extensively investigated by her general practitioner to establish the cause of her symptoms but all laboratory findings, cross-sectional imaging, ultrasound and oesophagogastroduodenoscopy to date were unremarkable. After being seen in gastroenterology outpatients' clinic, a colonoscopy was performed and was described as being macroscopically normal but microscopic evaluation of colonic biopsies suggested a possible 'resolving infection'. She was treated symptomatically, but within 6 months she represented to hospital with progressively worsening symptoms of severe abdominal pain, now associated with vomiting, followed by watery diarrhoea and then resolution of the symptoms. An abdominal CT scan was performed which showed a small intraluminal-filling defect in the mid-terminal ileum. A wireless capsule endoscopy was organised to further characterise the lesion although this was reported as showing no abnormality. Prior to any further outpatient investigations, she represented as an emergency to hospital in small bowel obstruction, underwent further cross-sectional imaging followed by surgical resection of the lesion. Histological characterisation revealed a small bowel inflammatory fibroid polyp. © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  irritable bowel syndrome; polyp; small bowel

Year:  2019        PMID: 32879725      PMCID: PMC7447279          DOI: 10.1136/flgastro-2019-101222

Source DB:  PubMed          Journal:  Frontline Gastroenterol        ISSN: 2041-4137


  13 in total

1.  Gastric submucosal granuloma with eosinophilic infiltration.

Authors:  J VANEK
Journal:  Am J Pathol       Date:  1949-05       Impact factor: 4.307

2.  Activating PDGFRA mutations in inflammatory fibroid polyps occur in exons 12, 14 and 18 and are associated with tumour localization.

Authors:  Sebastian Huss; Eva Wardelmann; Diane Goltz; Elke Binot; Wolfgang Hartmann; Sabine Merkelbach-Bruse; Reinhard Büttner; Hans-Ulrich Schildhaus
Journal:  Histopathology       Date:  2012-03-06       Impact factor: 5.087

3.  Diagnostic yield and clinical impact of wireless capsule endoscopy in patients with chronic abdominal pain with or without diarrhea: a Greek multicenter study.

Authors:  Panagiotis Katsinelos; Kostas Fasoulas; Athanasios Beltsis; Grigoris Chatzimavroudis; George Paroutoglou; Theofanis Maris; Kostas Mimidis; Alexandros Koufokotsios; Sotiris Terzoudis; Stefanos Atmatzidis; Agoritsa Kaltsa; Dimitris Kapetanos; Eustathios Kamperis; Christos Zavos; Jannis Kountouras; Aristea Belou
Journal:  Eur J Intern Med       Date:  2011-07-14       Impact factor: 4.487

4.  Accuracy of abdominal radiography in acute small-bowel obstruction: does reviewer experience matter?

Authors:  William M Thompson; Ramsey K Kilani; Benjamin B Smith; John Thomas; Tracy A Jaffe; David M Delong; Erik K Paulson
Journal:  AJR Am J Roentgenol       Date:  2007-03       Impact factor: 3.959

5.  Gain-of-function PDGFRA mutations, earlier reported in gastrointestinal stromal tumors, are common in small intestinal inflammatory fibroid polyps. A study of 60 cases.

Authors:  Jerzy Lasota; Zeng-Feng Wang; Leslie H Sobin; Markku Miettinen
Journal:  Mod Pathol       Date:  2009-05-15       Impact factor: 7.842

Review 6.  Irritable bowel syndrome diagnosis and management: A simplified algorithm for clinical practice.

Authors:  Paul Moayyedi; Fermín Mearin; Fernando Azpiroz; Viola Andresen; Giovanni Barbara; Maura Corsetti; Anton Emmanuel; A Pali S Hungin; Peter Layer; Vincenzo Stanghellini; Peter Whorwell; Frank Zerbib; Jan Tack
Journal:  United European Gastroenterol J       Date:  2017-09-28       Impact factor: 4.623

7.  Significant small-bowel lesions detected by alternative diagnostic modalities after negative capsule endoscopy.

Authors:  Aymer Postgate; Edward Despott; David Burling; Arun Gupta; Robin Phillips; James O'Beirne; David Patch; Chris Fraser
Journal:  Gastrointest Endosc       Date:  2008-12       Impact factor: 9.427

8.  Small bowel tumors detected and missed during capsule endoscopy: single center experience.

Authors:  Edyta S Zagorowicz; Anna M Pietrzak; Ewa Wronska; Jacek Pachlewski; Piotr Rutkowski; Ewa Kraszewska; Jaroslaw Regula
Journal:  World J Gastroenterol       Date:  2013-12-21       Impact factor: 5.742

9.  A case of giant inflammatory ileal polyp removed by double-balloon enteroscopy.

Authors:  Dae Woong Yoon; Beom Jae Lee; Jae Hyoung Lee; Jong-Jae Park; Jae Seon Kim; Young-Tae Bak; Won Jae Choi; Young Jae Mok
Journal:  Clin Endosc       Date:  2012-08-22

10.  Giant Inflammatory Fibroid Polyp of the Descending Colon Treated with Endoscopic Resection.

Authors:  Ammar Kayyali; Anis Toumeh; Usman Ahmad; Luis E De Las Casas; Ali Nawras
Journal:  ACG Case Rep J       Date:  2013-10-08
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