Yasuyo Fukushi1,2, Yasushi Mariya2,3, Kyogo Yamada4, Kazue Yoshida2, Asami Sasa2, Hitoshi Saito5, Ayumi Hirai6, Shigenori Suzuki6, Koichi Aizawa6, Hiroyuki Suganuma6, Chieko Itaki7. 1. Department of Disability and Health, Division of Health Sciences, Hirosaki University Graduate School of Health Sciences, Hirosaki, Japan. 2. Department of Radiology, Mutsu General Hospital, Mutsu, Japan. 3. Department of Radiation Oncology, Aomori Rosai Hospital, Hachinohe, Japan. 4. Department of Surgery, Mutsu General Hospital, Mutsu, Japan. 5. Department of Central laboratory, Mutsu General Hospital, Mutsu, Japan. 6. Innovation Division, Kagome Co., Ltd., Nasushiobara, Japan. 7. Department of Nursing Science, Hirosaki University Graduate School of Health Sciences, Hirosaki, Japan itakichi@hirosaki-u.ac.jp.
Abstract
BACKGROUND/AIM: We investigated the beneficial effects of drinking tomato juice (TJ) rich in antioxidant carotenoids on irradiated skin following radiotherapy (RT) in breast cancer patients. PATIENTS/ METHODS: Twenty-three patients agreed to drink TJ (160 g/day for six months) after the completion of RT. Early and late adverse events (AEs) of irradiated skin were evaluated according to the Common Terminology Criteria for AEs and the European Organization for Research and Treatment of Cancer Global Cosmetic Rating System, respectively. RESULTS: With regard to early AEs, acute radiodermatitis of grade 1 was observed in most patients (22/23) at the end of RT. However, the grade of radiodermatitis rapidly changed to 0, 1 month after RT and starting TJ consumption. With regard to late AEs, most patients were in good or excellent dermal condition. CONCLUSION: TJ consumption could help in relieving and recovering from early AEs and decreasing the severity of late AEs of irradiated skin. Copyright
BACKGROUND/AIM: We investigated the beneficial effects of drinking tomatojuice (TJ) rich in antioxidant carotenoids on irradiated skin following radiotherapy (RT) in breast cancerpatients. PATIENTS/ METHODS: Twenty-three patients agreed to drink TJ (160 g/day for six months) after the completion of RT. Early and late adverse events (AEs) of irradiated skin were evaluated according to the Common Terminology Criteria for AEs and the European Organization for Research and Treatment of Cancer Global Cosmetic Rating System, respectively. RESULTS: With regard to early AEs, acute radiodermatitis of grade 1 was observed in most patients (22/23) at the end of RT. However, the grade of radiodermatitis rapidly changed to 0, 1 month after RT and starting TJ consumption. With regard to late AEs, most patients were in good or excellent dermal condition. CONCLUSION: TJ consumption could help in relieving and recovering from early AEs and decreasing the severity of late AEs of irradiated skin. Copyright
Authors: Daniel Shepshelovich; Kate McDonald; Anna Spreafico; Albiruni R A Razak; Philippe L Bedard; Lillian L Siu; Lori Minasian; Aaron R Hansen Journal: Oncologist Date: 2019-02-06