Mert Esme1, Meltem Koca1, Ayse Dikmeer1, Cafer Balci2, Naim Ata3, Burcu Balam Dogu1, Mustafa Cankurtaran1, Meltem Yilmaz4, Osman Celik5, Gulnihal Gokce Unal3, Mustafa Mahir Ulgu5, Suayip Birinci6. 1. Faculty of Medicine, Department of Internal Medicine, Division of Geriatrics, Hacettepe University, Ankara, Turkey. 2. Department of Internal Medicine, Division of Geriatrics, Republic of Turkey Ministry of Health Eskişehir City Hospital, Eskişehir, Turkey. 3. Department of Strategy Development, Republic of Turkey Ministry of Health, Ankara, Turkey. 4. General Directorate of Health Information System, Republic of Turkey Ministry of Health, Ankara, Turkey. 5. General Directorate of Turkish Public Hospitals, Republic of Turkey Ministry of Health, Ankara, Turkey. 6. Deputy Minister, Republic of Turkey Ministry of Health, Ankara, Turkey.
Abstract
BACKGROUND: A novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) occurred in China in December 2019 and has spread globally. In this study, we aimed to describe the clinical characteristics and outcomes of hospitalized older adults with coronavirus disease 2019 (COVID-19) in Turkey. METHODS: We retrospectively analyzed the clinical data of hospitalized patients aged ≥ 60 years with confirmed COVID-19 from March 11, 2020 to May 27, 2020 using nationwide health database. RESULTS: In this nationwide cohort, a total of 16,942 hospitalized older adults with COVID-19 were enrolled, of whom 8,635 (51%) were women. Mean age was 71.2 ± 8.5 years, ranging from 60 to 113 years. Mortality rate before and after curfew was statistically different (32.2% vs. 17.9%; p < .001, respectively). Through multivariate analysis of the causes of death in older patients, we found that male gender, diabetes mellitus, heart failure, dementia, were all significantly associated with mortality in entire cohort. In addition to abovementioned risk factors, in patients aged between 60 and 79 years, hypertension, chronic kidney disease and cancer and in patients 80 years of age and older malnutrition were also associated with increased risk of mortality. CONCLUSIONS: In addition to the results of previous studies with smaller sample size, our results confirmed the age-related relationship between specific comorbidities and COVID-19-related mortality.
BACKGROUND: A novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) occurred in China in December 2019 and has spread globally. In this study, we aimed to describe the clinical characteristics and outcomes of hospitalized older adults with coronavirus disease 2019 (COVID-19) in Turkey. METHODS: We retrospectively analyzed the clinical data of hospitalized patients aged ≥ 60 years with confirmed COVID-19 from March 11, 2020 to May 27, 2020 using nationwide health database. RESULTS: In this nationwide cohort, a total of 16,942 hospitalized older adults with COVID-19 were enrolled, of whom 8,635 (51%) were women. Mean age was 71.2 ± 8.5 years, ranging from 60 to 113 years. Mortality rate before and after curfew was statistically different (32.2% vs. 17.9%; p < .001, respectively). Through multivariate analysis of the causes of death in older patients, we found that male gender, diabetes mellitus, heart failure, dementia, were all significantly associated with mortality in entire cohort. In addition to abovementioned risk factors, in patients aged between 60 and 79 years, hypertension, chronic kidney disease and cancer and in patients 80 years of age and older malnutrition were also associated with increased risk of mortality. CONCLUSIONS: In addition to the results of previous studies with smaller sample size, our results confirmed the age-related relationship between specific comorbidities and COVID-19-related mortality.
Authors: Nawfal R Hussein; Zana Sidiq M Saleem; Brisik H Rashad; Ibrahim A Naqid; Nashwan Ibrahim; Dildar H Musa; Nina D Khezaqia; Ahmed H Yousif Journal: J Family Med Prim Care Date: 2021-11-29
Authors: Sara S Jdiaa; Razan Mansour; Abdallah El Alayli; Archana Gautam; Preston Thomas; Reem A Mustafa Journal: J Nephrol Date: 2022-01-11 Impact factor: 3.902