Literature DB >> 3286622

Saccharomyces cerevisiae acquires resistance to 2-deoxyglucose at a very high frequency.

M F Heredia1, C F Heredia.   

Abstract

We have found that Saccharomyces cerevisiae acquires spontaneously increasing resistance to 2-deoxyglucose at a very high frequency. This finding allows the easy isolation of different types of resistant strains of interest for metabolic studies with 2-deoxyhexoses. On the other hand, it sounds a note of caution in the widespread use of 2-deoxyglucose as a selective agent for the isolation of yeast mutants with impaired hexose transport or phosphorylation systems.

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Year:  1988        PMID： 3286622      PMCID： PMC211217          DOI： 10.1128/jb.170.6.2870-2872.1988

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  11 in total

1.  METABOLIC STUDIES WITH 2-DEOXYHEXOSES. I. MECHANISMS OF INHIBITION OF GROWTH AND FERMENTATION IN BAKER'S YEAST.

Authors:  C F HEREDIA; G DELAFUENTE; A SOLS
Journal:  Biochim Biophys Acta       Date:  1964-05-11

2.  METABOLIC STUDIES WITH 2-DEOXYHEXOSES. II. RESISTANCE TO 2- DEOXYGLUCOSE IN A YEAST MUTANT.

Authors:  C F HEREDIA; A SOLS
Journal:  Biochim Biophys Acta       Date:  1964-05-11

3.  Hexokinase and other enzymes of sugar metabolism in the intestine.

Authors:  A SOLS; G DE LA FUENTE
Journal:  Methods Med Res       Date:  1961

4.  Substrate specificity and some other properties of baker's yeast hexokinase.

Authors:  A SOLS; G DE LA FUENTE; C VILLARPALASI; C ASENSIO
Journal:  Biochim Biophys Acta       Date:  1958-10

5.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

6.  Characterization of a phosphatase specific for 2-deoxyglucose-6-phosphate in a yeast mutant.

Authors:  M Martin; C F Heredia
Journal:  FEBS Lett       Date:  1977-11-15       Impact factor: 4.124

7.  Turnover of yeast fructose-bisphosphatase in different metabolic conditions.

Authors:  S Funayama; J M Gancedo; C Gancedo
Journal:  Eur J Biochem       Date:  1980-08

Review 8.  Gene amplification.

Authors:  G R Stark; G M Wahl
Journal:  Annu Rev Biochem       Date:  1984       Impact factor: 23.643

9.  Toxicity of 2-deoxygalactose to Saccharomyces cerevisiae cells constitutively synthesizing galactose-metabolizing enzymes.

Authors:  T Platt
Journal:  Mol Cell Biol       Date:  1984-05       Impact factor: 4.272

10.  Metabolism of 2-deoxy-D glucose by Baker's yeast. IV. Incorporation of 2-deoxy-D-glucose into cell wall mannan.

Authors:  P Biely; Z Krátký; S Bauer
Journal:  Biochim Biophys Acta       Date:  1972-02-11
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  5 in total

1.  Improved properties of baker's yeast mutants resistant to 2-deoxy-D-glucose.

Authors:  A M Rincón; A C Codón; F Castrejón; T Benítez
Journal:  Appl Environ Microbiol       Date:  2001-09       Impact factor: 4.792

2.  Genetic analysis of resistance and sensitivity to 2-deoxyglucose in Saccharomyces cerevisiae.

Authors:  Rhonda R McCartney; Dakshayini G Chandrashekarappa; Bob B Zhang; Martin C Schmidt
Journal:  Genetics       Date:  2014-08-12       Impact factor: 4.562

3.  Sugar repression in the methylotrophic yeast Hansenula polymorpha studied by using hexokinase-negative, glucokinase-negative and double kinase-negative mutants.

Authors:  T Kramarenko; H Karp; A Järviste; T Alamäe
Journal:  Folia Microbiol (Praha)       Date:  2000       Impact factor: 2.099

4.  Determination of the role of polyphosphate in transport-coupled phosphorylation in the yeast Saccharomyces cerevisiae.

Authors:  J Schuddemat; C C Van Leeuwen; J J Plijter; P J Van den Broek; J Van Steveninck
Journal:  Antonie Van Leeuwenhoek       Date:  1990-04       Impact factor: 2.271

5.  The expression of a specific 2-deoxyglucose-6P phosphatase prevents catabolite repression mediated by 2-deoxyglucose in yeast.

Authors:  F Randez-Gil; J A Prieto; P Sanz
Journal:  Curr Genet       Date:  1995-07       Impact factor: 3.886
  5 in total

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