Literature DB >> 328280

Subunit structure of the methionine-repressible aspartokinase II--homoserine dehydrogenase II from Escherichia coli K12.

A Dautry-Varsat, L Sibilli-Weill, G N Cohen.   

Abstract

The quaternary structure of Escherichia coli K12 aspartokinase II--homoserine dehydrogenase II has been examined. This multifunctional protein has a molecular weight Mr = 176000. It is composed of two subunits having the same molecular weight and the same charge. The results obtained from the examination of tryptic maps, the number and amino acid composition of cysteine-containing peptides and the uniqueness of the N-terminal sequence, strongly suggest that the 2 subunits are identical. The properties of aspartokinase II--homoserine dehydrogenase II can be compared to those of the much better known protein aspartokinase I--homoserine dehydrogenase I.

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Year:  1977        PMID： 328280     DOI： 10.1111/j.1432-1033.1977.tb11563.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN： 0014-2956


  6 in total

Review 1.  Linkage map of Escherichia coli K-12, edition 10: the traditional map.

Authors:  M K Berlyn
Journal:  Microbiol Mol Biol Rev       Date:  1998-09       Impact factor: 11.056

2.  The initial step in the archaeal aspartate biosynthetic pathway catalyzed by a monofunctional aspartokinase.

Authors:  Christopher R Faehnle; Xuying Liu; Alexander Pavlovsky; Ronald E Viola
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-09-30

3.  Construction and physical mapping of plasmids containing the metJBLF gene cluster of E. coli K12.

Authors:  M M Zakin; R C Greene; A Dautry-Varsat; N Duchange; P Ferrara; M C Py; D Margarita; G N Cohen
Journal:  Mol Gen Genet       Date:  1982

Review 4.  Linkage map of Escherichia coli K-12, edition 7.

Authors:  B J Bachmann
Journal:  Microbiol Rev       Date:  1983-06

5.  Localization of the metJBLF gene cluster of Escherichia coli in lambda met transducing phage.

Authors:  R C Greene; J H Krueger; J R Johnson
Journal:  Mol Gen Genet       Date:  1982

6.  Structural studies of lambda transducing bacteriophage carrying bacterial deoxyribonucleic acid from the metBJLF region of the Escherichia coli chromosome.

Authors:  J H Krueger; J R Johnson; R C Greene; M Dresser
Journal:  J Bacteriol       Date:  1981-08       Impact factor: 3.490
  6 in total

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