Literature DB >> 32826719

Containment of a Large SARS-CoV-2 Outbreak Among Healthcare Workers in a Pediatric Intensive Care Unit.

Rebecca Luise Knoll1, Jonas Klopp1, Gloria Bonewitz1, Britta Gröndahl1, Katja Hilbert1, Wolfgang Kohnen2, Kerstin Weise3, Bodo Plachter3, Walter Hitzler4, Frank Kowalzik1, Stefan Runkel4, Fred Zepp1, Julia Winter1, Maximiliano Luis Cacicedo1, Stephan Gehring1.   

Abstract

OBJECTIVE: Healthcare workers (HCWs) are particularly exposed SARS-CoV-2 because they are critical in preventing viral transmission and treating COVID-19 patients. Within HCWs, personnel of intensive care units (ICUs) are at the forefront of treating patients with a severe course of COVID-19 infection and therefore represent an extremely vulnerable group. Thus, our objective is to contribute to establish means of infection control protecting HCWs in the frontline of the current pandemic.
DESIGN: An outbreak of SARS-CoV-2 was detected and contained in a pediatric ICU (PICU). The first positive case was identified with a point-of-care diagnostic system on site. Real-time PCR-based testing systems from self-collected nasopharyngeal samples swabs were used to test for viral RNA of SARS-CoV-2 in the follow-up.
SETTING: PICU within a tertiary university hospital in Germany. PARTICIPANTS: Healthcare workers of the PICU.
INTERVENTIONS: Positive HCWs were sent into quarantine. Containment measures were implemented including wearing of surgical-masks, physical distancing and systematic testing.
RESULTS: Among 432 HCWs, 91 (25%) were tested. Forty-five percent reported symptoms corresponding to characteristics of COVID-19. Of those, only 19,5% (8 HCWs) were tested positive for SARS-CoV-2. No infection occurred outside the PICU. After the implementation of containment measures, viral transmission was stopped.
CONCLUSIONS: In the present study, a large outbreak within a team of healthcare workers of a PICU, affecting almost one fifth of the entire personnel is documented, along with detailed insights about how the outbreak was contained and how operability of the unit was maintained.

Entities:  

Mesh:

Year:  2020        PMID: 32826719     DOI: 10.1097/INF.0000000000002866

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN: 0891-3668            Impact factor:   2.129


  7 in total

1.  Cross-sectional prevalence of SARS-CoV-2 antibodies in healthcare workers in paediatric facilities in eight countries.

Authors:  D Goldblatt; M Johnson; O Falup-Pecurariu; I Ivaskeviciene; V Spoulou; E Tamm; M Wagner; H J Zar; L Bleotu; R Ivaskevicius; I Papadatou; P Jõgi; J Lischka; Z Franckling-Smith; D Isarova; L Grandjean; D Zavadska
Journal:  J Hosp Infect       Date:  2021-01-07       Impact factor: 3.926

2.  COVID-19 containment on a college campus via wastewater-based epidemiology, targeted clinical testing and an intervention.

Authors:  Walter Q Betancourt; Bradley W Schmitz; Gabriel K Innes; Sarah M Prasek; Kristen M Pogreba Brown; Erika R Stark; Aidan R Foster; Ryan S Sprissler; David T Harris; Samendra P Sherchan; Charles P Gerba; Ian L Pepper
Journal:  Sci Total Environ       Date:  2021-03-13       Impact factor: 7.963

3.  Reliable detection of SARS-CoV-2 with patient-collected swabs and saline gargles: A three-headed comparison on multiple molecular platforms.

Authors:  Jason J LeBlanc; Janice Pettipas; Melanie Di Quinzio; Todd F Hatchette; Glenn Patriquin
Journal:  J Virol Methods       Date:  2021-05-23       Impact factor: 2.623

4.  The case for wearable proximity devices to inform physical distancing among healthcare workers.

Authors:  Sara C Keller; Alejandra B Salinas; Opeyemi Oladapo-Shittu; Sara E Cosgrove; Robin Lewis-Cherry; Patience Osei; Ayse P Gurses; Ron Jacak; Kristina K Zudock; Kianna M Blount; Kenneth V Bowden; Clare Rock; Anna C Sick-Samuels; Briana Vecchio-Pagan
Journal:  JAMIA Open       Date:  2021-11-30

5.  Safety and health management response to COVID-19 in the construction industry: A perspective of fieldworkers.

Authors:  Chukwuma Nnaji; Ziyu Jin; Ali Karakhan
Journal:  Process Saf Environ Prot       Date:  2022-01-05       Impact factor: 6.158

Review 6.  COVID-19 Prevention and Control Measures in Workplace Settings: A Rapid Review and Meta-Analysis.

Authors:  Carolyn Ingram; Vicky Downey; Mark Roe; Yanbing Chen; Mary Archibald; Kadri-Ann Kallas; Jaspal Kumar; Peter Naughton; Cyril Onwuelazu Uteh; Alejandro Rojas-Chaves; Shibu Shrestha; Shiraz Syed; Fionn Cléirigh Büttner; Conor Buggy; Carla Perrotta
Journal:  Int J Environ Res Public Health       Date:  2021-07-24       Impact factor: 4.614

7.  COVID-19 Transmission and Clinical Features in Pediatric Intensive Care Health Care Workers.

Authors:  Edin Botan; Emel Uyar; Zeynelabidin Öztürk; Esra Şevketoğlu; Yusuf Sarı; Oğuz Dursun; Şahin Sincar; Muhterem Duyu; Arzu Oto; Mehmet Celegen; Gökçen Özçiftçi; Merve Havan; Makbule Nilüfer Öztürk; Hasan Ağın; Nazik Yener; Ayhan Yaman; Emrah Gün; Merve Yılmaz; Naile Şimşek; Halil Özdemir; Dinçer Yıldızdaş; Tanıl Kendirli
Journal:  Turk Arch Pediatr       Date:  2022-01
  7 in total

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