| Literature DB >> 32814938 |
Zhuangyu Zhao1, Benjamin W Roose1, Serge D Zemerov1, Madison A Stringer1, Ivan J Dmochowski1.
Abstract
Detection of protein-protein interactions (PPIs) is limited by current bioanalytical methods. A protein complementation assay (PCA), split TEM-1 β-lactamase, interacts with xenon at the interface of the TEM-1 fragments. Reconstitution of TEM-1-promoted here by cFos/cJun leucine zipper interaction-gives rise to sensitive 129Xe NMR signal in bacterial cells.Entities:
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Year: 2020 PMID: 32814938 PMCID: PMC7511426 DOI: 10.1039/d0cc02988b
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222