Literature DB >> 3280907

Imipenem: a new carbapenem antibiotic.

B Lipman1, H C Neu.   

Abstract

Imipenem is a new carbapenem antibiotic that has an extremely broad spectrum of antibacterial activity. It has been used to treat a variety of serious infections and an increasing volume of literature documents its value in infections due to multiresistant bacteria. This article reviews the antibacterial activity, pharmacology, and clinical uses of imipenem.

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Year:  1988        PMID： 3280907     DOI： 10.1016/s0025-7125(16)30759-3

Source DB:  PubMed          Journal:  Med Clin North Am        ISSN： 0025-7125            Impact factor:   5.456


  4 in total

1.  In vitro and in vivo activities of LJC10,627, a new carbapenem with stability to dehydropeptidase I.

Authors:  P J Petersen; N V Jacobus; W J Weiss; R T Testa
Journal:  Antimicrob Agents Chemother       Date:  1991-01       Impact factor: 5.191

2.  In vitro activity and beta-lactamase stability of a new carbapenem, SM-7338.

Authors:  H C Neu; A Novelli; N X Chin
Journal:  Antimicrob Agents Chemother       Date:  1989-07       Impact factor: 5.191

3.  Low neurotoxicity of LJC 10,627, a novel 1 beta-methyl carbapenem antibiotic: inhibition of gamma-aminobutyric acidA, benzodiazepine, and glycine receptor binding in relation to lack of central nervous system toxicity in rats.

Authors:  M Hikida; Y Masukawa; K Nishiki; N Inomata
Journal:  Antimicrob Agents Chemother       Date:  1993-02       Impact factor: 5.191

4.  Celecoxib Enhances the Efficacy of Low-Dose Antibiotic Treatment against Polymicrobial Sepsis in Mice and Clinical Isolates of ESKAPE Pathogens.

Authors:  Madhavi Annamanedi; Gajapati Y N Varma; K Anuradha; Arunasree M Kalle
Journal:  Front Microbiol       Date:  2017-05-08       Impact factor: 5.640
  4 in total

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