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Literature DB >> 32803757

A hairy tale: SIRT7 safeguards skin stem cells during aging.

Matthew Simon¹, Stephan Emmrich¹, Andrei Seluanov^1,2, Vera Gorbunova^1,2.

Abstract

Stem cell regulation during both normal development and aging has become one of the fastest growing topics in biology. Here, new work by Li et al (2020) offers insight into the aging process within epithelial skin stem cells and highlights how SIRT7, a member of the sirtuin family of protein deacylases and mono-ADP ribosylases, protects adult hair follicle stem cells from aging by ensuring their hair cycle progression.

Entities: Gene

Mesh：

Substances：

Year: 2020 PMID： 32803757 PMCID： PMC7507574 DOI： 10.15252/embj.2020106294

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 11.598

13 in total

1. Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis.

Authors: Hiroyuki Matsumura; Yasuaki Mohri; Nguyen Thanh Binh; Hironobu Morinaga; Makoto Fukuda; Mayumi Ito; Sotaro Kurata; Jan Hoeijmakers; Emi K Nishimura
Journal: Science Date: 2016-02-04 Impact factor: 47.728

2. A hairy tale: SIRT7 safeguards skin stem cells during aging.

Authors: Matthew Simon; Stephan Emmrich; Andrei Seluanov; Vera Gorbunova
Journal: EMBO J Date: 2020-08-16 Impact factor: 11.598

3. SIRT6 promotes DNA repair under stress by activating PARP1.

Authors: Zhiyong Mao; Christopher Hine; Xiao Tian; Michael Van Meter; Matthew Au; Amita Vaidya; Andrei Seluanov; Vera Gorbunova
Journal: Science Date: 2011-06-17 Impact factor: 47.728

4. Stem cell aging. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging.

Authors: Mary Mohrin; Jiyung Shin; Yufei Liu; Katharine Brown; Hanzhi Luo; Yannan Xi; Cole M Haynes; Danica Chen
Journal: Science Date: 2015-03-20 Impact factor: 47.728

5. The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability.

Authors: Silvana Paredes; Maria Angulo-Ibanez; Luisa Tasselli; Scott M Carlson; Wei Zheng; Tie-Mei Li; Katrin F Chua
Journal: J Biol Chem Date: 2018-05-04 Impact factor: 5.157

6. SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation.

Authors: Matthew F Barber; Eriko Michishita-Kioi; Yuanxin Xi; Luisa Tasselli; Mitomu Kioi; Zarmik Moqtaderi; Ruth I Tennen; Silvana Paredes; Nicolas L Young; Kaifu Chen; Kevin Struhl; Benjamin A Garcia; Or Gozani; Wei Li; Katrin F Chua
Journal: Nature Date: 2012-07-05 Impact factor: 49.962

7. SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer.

Authors: Shijia Bi; Zunpeng Liu; Zeming Wu; Zehua Wang; Xiaoqian Liu; Si Wang; Jie Ren; Yan Yao; Weiqi Zhang; Moshi Song; Guang-Hui Liu; Jing Qu
Journal: Protein Cell Date: 2020-06-06 Impact factor: 14.870

8. SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair.

Authors: Ming Tang; Zhiming Li; Chaohua Zhang; Xiaopeng Lu; Bo Tu; Ziyang Cao; Yinglu Li; Yongcan Chen; Lu Jiang; Hui Wang; Lina Wang; Jiadong Wang; Baohua Liu; Xingzhi Xu; Haiying Wang; Wei-Guo Zhu
Journal: Sci Adv Date: 2019-03-27 Impact factor: 14.136

9. SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina.

Authors: Berta N Vazquez; Joshua K Thackray; Nicolas G Simonet; Sanjay Chahar; Noriko Kane-Goldsmith; Simon J Newkirk; Suman Lee; Jinchuan Xing; Michael P Verzi; Wenfeng An; Alejandro Vaquero; Jay A Tischfield; Lourdes Serrano
Journal: Nucleic Acids Res Date: 2019-09-05 Impact factor: 16.971