Literature DB >> 3280189

Synthesis of interleukin-1-like activity by normal rat chondrocytes in culture.

N C Rath1, A L Oronsky, S S Kerwar.   

Abstract

Chondrocytes prepared from the articular cartilage of young rats synthesize and secrete an interleukin-1-like activity into the medium. The physical and biochemical properties of this IL-1-like activity are similar to macrophage-derived IL-1. Immunological studies suggest that this activity is related to IL-1 alpha. Isolated chondrocytes and those grown in culture can express Ia.

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Year:  1988        PMID： 3280189     DOI： 10.1016/0090-1229(88)90143-2

Source DB:  PubMed          Journal:  Clin Immunol Immunopathol        ISSN： 0090-1229


  7 in total

1.  Expression of ICAM-1 on intact cartilage and isolated chondrocytes.

Authors:  J Bujia; U Behrends; N Rotter; P Pitzke; E Wilmes; C Hammer
Journal:  In Vitro Cell Dev Biol Anim       Date:  1996-02       Impact factor: 2.416

Review 2.  Cytokines and proteoglycans.

Authors:  J J Nietfeld
Journal:  Experientia       Date:  1993-05-15

3.  Effect of interleukin-1-beta and tumor necrosis factor-alpha on cartilage proteoglycan metabolism in vitro.

Authors:  M A Pratta; T M Di Meo; D M Ruhl; E C Arner
Journal:  Agents Actions       Date:  1989-06

4.  In vitro effects of hyaluronan on prostaglandin E2 induction by interleukin-1 in rabbit articular chondrocytes.

Authors:  M Akatsuka; Y Yamamoto; K Tobetto; T Yasui; T Ando
Journal:  Agents Actions       Date:  1993-01

5.  Recombinant human interleukin-1 alpha and recombinant human interleukin-1 beta stimulate cartilage matrix degradation and inhibit glycosaminoglycan synthesis.

Authors:  R J Smith; N A Rohloff; L M Sam; J M Justen; M R Deibel; J C Cornette
Journal:  Inflammation       Date:  1989-08       Impact factor: 4.092

6.  Effects of interleukin-1 on syntheses of alkaline phosphatase, type X collagen, and 1,25-dihydroxyvitamin D3 receptor, and matrix calcification in rabbit chondrocyte cultures.

Authors:  Y Kato; K Nakashima; M Iwamoto; H Murakami; H Hiranuma; T Koike; F Suzuki; H Fuchihata; Y Ikehara; M Noshiro
Journal:  J Clin Invest       Date:  1993-11       Impact factor: 14.808

7.  Detection of tumour necrosis factor alpha and interleukin-1 beta in the rheumatoid osteoarthritic cartilage-pannus junction by immunohistochemical methods.

Authors:  V E Miller; K Rogers; K D Muirden
Journal:  Rheumatol Int       Date:  1993       Impact factor: 2.631
  7 in total

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