Raphael Mendes Ritti-Dias1, Fernando da Silva Sant'anna2, Heloisa Amaral Braghieri3, Nelson Wolosker4, Pedro Puech-Leao5, Fernanda Cordoba Lanza6, Gabriel Grizzo Cucato7, Simone Dal Corso3, Marilia Almeida Correia2. 1. Graduated Program in Rehabilitation Sciences, Universidade Nove de Julho, São Paulo Brazil. Electronic address: raphaelritti@gmail.com. 2. Graduated Program in Medicine, Universidade Nove de Julho, São Paulo, Brazil. 3. Graduated Program in Rehabilitation Sciences, Universidade Nove de Julho, São Paulo Brazil. 4. Graduate Program of Health Sciences, Instituto Israelita de Ensino e Pesquisa, São Paulo, Brazil. 5. Department of Vascular Surgery, Hospital das Clínicas da Universidade de São Paulo, São Paulo, Brazil. 6. Federal University of Minas Gerais, Belo Horizonte, Brazil. 7. Department of Sport, Exercise and Rehabilitation, Northumbria University, Newcastle upon Tyne, UK.
Abstract
BACKGROUND: Six-min walking test (6MWT) has been widely in patients with symptomatic peripheral artery disease (PAD) to quantify the walking impairment and the efficacy of different therapeutic interventions. Despite the aforementioned usefulness of 6MWT for PAD, the information provided by this test goes beyond the meters walked. The aim of this study was to describe the relative values of 6MWT and body weight-walking distance product (DW) in patients with symptomatic PAD. METHODS: Two hundred twenty-seven patients with symptomatic PAD participated in the study. The 6MWT was performed and absolute and claudication distances were obtained. The results of 6MWT were then relativized and expressed as a percentage of a healthy subject. DW was obtained by the product of 6MWT distance by weight. In both sexes, the relative 6MWT ranged from 57% to 64%. RESULTS: Absolute 6MWT total distance (P < 0.001) was lower in women than in men, whereas the relative 6MWT total distance was similar between sexes (P = 0.398). The absolute and relative 6MWT total distance were similar among age categories (P > 0.072). The DW was higher in men than in women (P < 0.05). In addition, in women, DW was higher in younger group than in other age groups (P < 0.05). CONCLUSIONS: Patients with symptomatic PAD achieve less than 70% of the distance achieved by an age-matched healthy subject. In patients with symptomatic PAD, the relative values of 6MWT total distance are similar between sexes and among different age groups, whereas DW are influenced by age and sex.
BACKGROUND: Six-min walking test (6MWT) has been widely in patients with symptomatic peripheral artery disease (PAD) to quantify the walking impairment and the efficacy of different therapeutic interventions. Despite the aforementioned usefulness of 6MWT for PAD, the information provided by this test goes beyond the meters walked. The aim of this study was to describe the relative values of 6MWT and body weight-walking distance product (DW) in patients with symptomatic PAD. METHODS: Two hundred twenty-seven patients with symptomatic PAD participated in the study. The 6MWT was performed and absolute and claudication distances were obtained. The results of 6MWT were then relativized and expressed as a percentage of a healthy subject. DW was obtained by the product of 6MWT distance by weight. In both sexes, the relative 6MWT ranged from 57% to 64%. RESULTS: Absolute 6MWT total distance (P < 0.001) was lower in women than in men, whereas the relative 6MWT total distance was similar between sexes (P = 0.398). The absolute and relative 6MWT total distance were similar among age categories (P > 0.072). The DW was higher in men than in women (P < 0.05). In addition, in women, DW was higher in younger group than in other age groups (P < 0.05). CONCLUSIONS:Patients with symptomatic PAD achieve less than 70% of the distance achieved by an age-matched healthy subject. In patients with symptomatic PAD, the relative values of 6MWT total distance are similar between sexes and among different age groups, whereas DW are influenced by age and sex.
Authors: Juliana Carvalho; Marilia A Correia; Hélcio Kanegusuku; Paulo Longano; Nelson Wolosker; Raphael M Ritti-Dias; Gabriel Grizzo Cucato Journal: PLoS One Date: 2022-09-09 Impact factor: 3.752