Literature DB >> 3280080

Flutamide versus stilboestrol in the management of advanced prostatic cancer. A controlled prospective study.

F Lund1, F Rasmussen.   

Abstract

In a prospective randomised study the effect of flutamide 750 mg daily was compared with that of stilboestrol 3 mg daily in the treatment of 40 previously untreated patients with advanced prostatic cancer. There was a good subjective response to both treatments. After 12 months, a response was demonstrated in 13 of 20 patients treated with flutamide and 8 of 20 patients treated with stilboestrol. The difference was not statistically significant. Treatment with stilboestrol caused more frequent, and more severe, side effects than flutamide.

Entities:  

Mesh:

Substances:

Year:  1988        PMID: 3280080     DOI: 10.1111/j.1464-410x.1988.tb05062.x

Source DB:  PubMed          Journal:  Br J Urol        ISSN: 0007-1331


  13 in total

1.  Complete androgen blockade as primary treatment for advanced metastatic cancer of the prostate.

Authors:  J F Larsen; S Walter; T Krarup
Journal:  Int Urol Nephrol       Date:  1990       Impact factor: 2.370

Review 2.  [Problems and principles of hormone therapy of advanced prostate cancer].

Authors:  J E Altwein; P Faul
Journal:  Klin Wochenschr       Date:  1990-04-02

Review 3.  Estrogen therapy in patients with prostate cancer: a contemporary systematic review.

Authors:  Leonardo Oliveira Reis; Emerson Luis Zani; Herney Andrés García-Perdomo
Journal:  Int Urol Nephrol       Date:  2018-03-29       Impact factor: 2.370

Review 4.  Flutamide. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in advanced prostatic cancer.

Authors:  R N Brogden; S P Clissold
Journal:  Drugs       Date:  1989-08       Impact factor: 9.546

Review 5.  The effects of testosterone on the cavernous tissue and erectile function.

Authors:  R Shabsigh
Journal:  World J Urol       Date:  1997       Impact factor: 4.226

6.  A Randomized Control Trial Comparing the Efficacy of Antiandrogen Monotherapy: Flutamide vs. Bicalutamide.

Authors:  Yasushi Nakai; Nobumichi Tanaka; Satoshi Anai; Makito Miyake; Yoshihiro Tatsumi; Kiyohide Fujimoto
Journal:  Horm Cancer       Date:  2015-05-30       Impact factor: 3.869

7.  Flutamide-induced toxic hepatitis. Potential utility of ursodeoxycholic acid administration in toxic hepatitis.

Authors:  C Cicognani; M Malavolti; A M Morselli-Labate; C Sama; L Barbara
Journal:  Dig Dis Sci       Date:  1996-11       Impact factor: 3.199

Review 8.  Flutamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in advanced prostatic cancer.

Authors:  R N Brogden; P Chrisp
Journal:  Drugs Aging       Date:  1991-03       Impact factor: 3.923

Review 9.  Hormonal therapy for stage D cancer of the prostate.

Authors:  M R Gudziak; A Y Smith
Journal:  West J Med       Date:  1994-04

Review 10.  Cardiovascular risks and toxicity - The Achilles heel of androgen deprivation therapy in prostate cancer patients.

Authors:  Sakthivel Muniyan; Lei Xi; Kaustubh Datta; Anindita Das; Benjamin A Teply; Surinder K Batra; Rakesh C Kukreja
Journal:  Biochim Biophys Acta Rev Cancer       Date:  2020-06-11       Impact factor: 10.680

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.