Literature DB >> 3279018

Oxygen-independent bactericidal systems. Mechanisms and disorders.

R I Lehrer1, T Ganz, M E Selsted.   

Abstract

Neutrophils contain microbicidal proteins packaged in numerous cytoplasmic granules. During phagocytosis, granules fuse to phagolysosomes where the granule contents contribute to the destruction and dissolution of ingested bacteria. The properties of the microbicidal proteins cathepsin G, BPI, and defensins are described and contrasted.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3279018

Source DB:  PubMed          Journal:  Hematol Oncol Clin North Am        ISSN： 0889-8588            Impact factor:   3.722


  13 in total

1.  Magainins and the disruption of membrane-linked free-energy transduction.

Authors:  H V Westerhoff; D Juretić; R W Hendler; M Zasloff
Journal:  Proc Natl Acad Sci U S A       Date:  1989-09       Impact factor: 11.205

2.  Antimicrobial activity of rabbit leukocyte defensins against Treponema pallidum subsp. pallidum.

Authors:  L A Borenstein; M E Selsted; R I Lehrer; J N Miller
Journal:  Infect Immun       Date:  1991-04       Impact factor: 3.441

3.  Cryopreservable neutrophil surrogates. Stored cytoplasts from human polymorphonuclear leukocytes retain chemotactic, phagocytic, and microbicidal function.

Authors:  S E Malawista; G Van Blaricom; M G Breitenstein
Journal:  J Clin Invest       Date:  1989-02       Impact factor: 14.808

4.  Large-scale synthesis and functional elements for the antimicrobial activity of defensins.

Authors:  P A Raj; K J Antonyraj; T Karunakaran
Journal:  Biochem J       Date:  2000-05-01       Impact factor: 3.857

5.  Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity.

Authors:  R I Lehrer; A Barton; K A Daher; S S Harwig; T Ganz; M E Selsted
Journal:  J Clin Invest       Date:  1989-08       Impact factor: 14.808

6.  Paneth cell alpha-defensins from rhesus macaque small intestine.

Authors:  Hiroki Tanabe; Jun Yuan; Melinda M Zaragoza; Satya Dandekar; Agnes Henschen-Edman; Michael E Selsted; Andre J Ouellette
Journal:  Infect Immun       Date:  2004-03       Impact factor: 3.441

7.  Septicemia-inducing Escherichia coli O115:K"V165"F165(1) resists killing by porcine polymorphonuclear leukocytes in vitro: role of F165(1) fimbriae and K"V165" O-antigen capsule.

Authors:  M Ngeleka; B Martineau-Doizé; J M Fairbrother
Journal:  Infect Immun       Date:  1994-02       Impact factor: 3.441

8.  The use of antimicrobial peptides in ophthalmology: an experimental study in corneal preservation and the management of bacterial keratitis.

Authors:  Mark J Mannis
Journal:  Trans Am Ophthalmol Soc       Date:  2002

9.  Electropositive charge in alpha-defensin bactericidal activity: functional effects of Lys-for-Arg substitutions vary with the peptide primary structure.

Authors:  R Alan Llenado; Colby S Weeks; Melanie J Cocco; André J Ouellette
Journal:  Infect Immun       Date:  2009-09-08       Impact factor: 3.441

10.  Chloride transport in functionally active phagosomes isolated from Human neutrophils.

Authors:  Martha L Aiken; Richard G Painter; Yun Zhou; Guoshun Wang
Journal:  Free Radic Biol Med       Date:  2012-10-23       Impact factor: 7.376
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.