Literature DB >> 3278958

Chemical and biological properties of indole glucosinolates (glucobrassicins): a review.

R McDanell1, A E McLean, A B Hanley, R K Heaney, G R Fenwick.   

Abstract

Glucosinolates are a group of secondary products commonly, but not exclusively, found in plants of the family Cruciferae. They give rise, upon enzymic hydrolysis, to a range of volatile, pungent and physiologically active compounds. Recently, particular attention has been focused upon those that are trytophan-derived--the indole glucosinolates (glucobrassicins). When chemically or enzymically hydrolysed these compounds give rise to a range of involatile indole compounds which have been implicated in the anti-carcinogenic and mixed-function-oxidase stimulatory activities of brassica vegetables. This review details the chemical and physiological properties of indole glucosinolates and their products and suggests possible areas for future research.

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Year:  1988        PMID: 3278958     DOI: 10.1016/0278-6915(88)90042-7

Source DB:  PubMed          Journal:  Food Chem Toxicol        ISSN: 0278-6915            Impact factor:   6.023


  28 in total

1.  Nature's chemicals and synthetic chemicals: comparative toxicology.

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2.  Dietary pesticides (99.99% all natural).

Authors:  B N Ames; M Profet; L S Gold
Journal:  Proc Natl Acad Sci U S A       Date:  1990-10       Impact factor: 11.205

Review 3.  The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention.

Authors:  David E Williams
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2011-06-16       Impact factor: 3.228

4.  Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis.

Authors:  Xuemin Qian; Tamene Melkamu; Pramod Upadhyaya; Fekadu Kassie
Journal:  Cancer Lett       Date:  2011-07-02       Impact factor: 8.679

Review 5.  The Role of Non-Coding RNAs and Isothiocyanates in Cancer.

Authors:  Samantha L Martin; Kendra J Royston; Trygve O Tollefsbol
Journal:  Mol Nutr Food Res       Date:  2018-05-28       Impact factor: 5.914

6.  Reciprocal responses in the interaction between Arabidopsis and the cell-content-feeding chelicerate herbivore spider mite.

Authors:  Vladimir Zhurov; Marie Navarro; Kristie A Bruinsma; Vicent Arbona; M Estrella Santamaria; Marc Cazaux; Nicky Wybouw; Edward J Osborne; Cherise Ens; Cristina Rioja; Vanessa Vermeirssen; Ignacio Rubio-Somoza; Priti Krishna; Isabel Diaz; Markus Schmid; Aurelio Gómez-Cadenas; Yves Van de Peer; Miodrag Grbic; Richard M Clark; Thomas Van Leeuwen; Vojislava Grbic
Journal:  Plant Physiol       Date:  2013-11-27       Impact factor: 8.340

Review 7.  The cancer chemopreventive actions of phytochemicals derived from glucosinolates.

Authors:  John D Hayes; Michael O Kelleher; Ian M Eggleston
Journal:  Eur J Nutr       Date:  2008-05       Impact factor: 5.614

8.  Suppression of inflammatory mediators by cruciferous vegetable-derived indole-3-carbinol and phenylethyl isothiocyanate in lipopolysaccharide-activated macrophages.

Authors:  Jo-Ting Tsai; Hui-Ching Liu; Yue-Hwa Chen
Journal:  Mediators Inflamm       Date:  2010-04-13       Impact factor: 4.711

9.  Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Authors:  L F Bjeldanes; J Y Kim; K R Grose; J C Bartholomew; C A Bradfield
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-01       Impact factor: 11.205

10.  Photoaffinity labelling of steroid-hormone-binding glutathione S-transferases with [3H]methyltrienolone. Inhibition of steroid-binding activity by the anticarcinogen indole-3-carbinol.

Authors:  D P Danger; W S Baldwin; G A LeBlanc
Journal:  Biochem J       Date:  1992-12-01       Impact factor: 3.857

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