Literature DB >> 3278904

Excision of apurinic and/or apyrimidinic sites from DNA by nucleolytical enzymes from rat brain.

V A Ivanov1, T M Tretyak, Y N Afonin.   

Abstract

Apurinic and/or apyrimidinic (AP) sites were excised from PM2 phage DNA by two enzymes: an AP endodeoxyribonuclease isolated from rat neocortex chromatin and a rat brain exodeoxyribonuclease, DNase B III. The resulting gap was filled with DNA polymerase beta prepared from rat liver and finally ligated by Escherichia coli DNA ligase.

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Year:  1988        PMID: 3278904     DOI: 10.1111/j.1432-1033.1988.tb13867.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN: 0014-2956


  2 in total

Review 1.  Genomic damage and its repair in young and aging brain.

Authors:  K S Rao
Journal:  Mol Neurobiol       Date:  1993       Impact factor: 5.590

2.  Purification and characterization of a deoxy-ribonuclease acting on native and UV irradiated DNA from young and aging rat brain.

Authors:  E Suvarchala; K S Rao
Journal:  Mol Cell Biochem       Date:  1994-08-31       Impact factor: 3.396

  2 in total

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