Literature DB >> 3278516

Residual motor functions in spinal cord injury.

M R Dimitrijević1.   

Abstract

After acute spinal cord injury, only 10% of the patients experience significant functional recovery. The remaining 90% reveal numerous varieties of spinal cord dysfunctions with different degrees of incomplete and unsatisfactory recovery of functional usage. In such cases of partial recovery of spinal cord functions, a certain degree of restitution of functions can be achieved. By studying these patients and their neurocontrol, we can learn that there are minimal requirements for the restitution of brain influence on segmental mechanisms and that different degrees of control can exist and contribute to the control of steps. These cases exemplify that upper motor neuron paresis is not only a weaker control owing to the loss of a certain percentage of functional fibers: it is an alternative in neurocontrol resulting from suprasegmental and segmental mechanisms within residual structures and their functional performance. On the basis of our observations we conclude that in addition to the model of the "transected spinal cord injury" and the model of the partially injured spinal cord, there is a third model with "discomplete lesion," indicating that it is necessary to revise the conventional concept of "released segmental functions" in patients with transected spinal cord lesion.

Entities:  

Mesh:

Year:  1988        PMID: 3278516

Source DB:  PubMed          Journal:  Adv Neurol        ISSN: 0091-3952


  12 in total

Review 1.  Application of electrophysiological measures in spinal cord injury clinical trials: a narrative review.

Authors:  Michèle Hubli; John L K Kramer; Catherine R Jutzeler; Jan Rosner; Julio C Furlan; Keith E Tansey; Martin Schubert
Journal:  Spinal Cord       Date:  2019-07-23       Impact factor: 2.772

2.  Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans.

Authors:  Claudia A Angeli; V Reggie Edgerton; Yury P Gerasimenko; Susan J Harkema
Journal:  Brain       Date:  2014-04-08       Impact factor: 13.501

Review 3.  Early microvascular reactions and blood-spinal cord barrier disruption are instrumental in pathophysiology of spinal cord injury and repair: novel therapeutic strategies including nanowired drug delivery to enhance neuroprotection.

Authors:  Hari Shanker Sharma
Journal:  J Neural Transm (Vienna)       Date:  2010-12-16       Impact factor: 3.575

Review 4.  Targeted-Plasticity in the Corticospinal Tract After Human Spinal Cord Injury.

Authors:  Lasse Christiansen; Monica A Perez
Journal:  Neurotherapeutics       Date:  2018-07       Impact factor: 7.620

5.  Effects of Lumbosacral Spinal Cord Epidural Stimulation for Standing after Chronic Complete Paralysis in Humans.

Authors:  Enrico Rejc; Claudia Angeli; Susan Harkema
Journal:  PLoS One       Date:  2015-07-24       Impact factor: 3.240

6.  Training with brain-machine interfaces, visuo-tactile feedback and assisted locomotion improves sensorimotor, visceral, and psychological signs in chronic paraplegic patients.

Authors:  Solaiman Shokur; Ana R C Donati; Debora S F Campos; Claudia Gitti; Guillaume Bao; Dora Fischer; Sabrina Almeida; Vania A S Braga; Patricia Augusto; Chris Petty; Eduardo J L Alho; Mikhail Lebedev; Allen W Song; Miguel A L Nicolelis
Journal:  PLoS One       Date:  2018-11-29       Impact factor: 3.240

7.  Alterations of Spinal Epidural Stimulation-Enabled Stepping by Descending Intentional Motor Commands and Proprioceptive Inputs in Humans With Spinal Cord Injury.

Authors:  Megan L Gill; Margaux B Linde; Rena F Hale; Cesar Lopez; Kalli J Fautsch; Jonathan S Calvert; Daniel D Veith; Lisa A Beck; Kristin L Garlanger; Dimitry G Sayenko; Igor A Lavrov; Andrew R Thoreson; Peter J Grahn; Kristin D Zhao
Journal:  Front Syst Neurosci       Date:  2021-01-28

8.  Spinal Cord Imaging Markers and Recovery of Volitional Leg Movement With Spinal Cord Epidural Stimulation in Individuals With Clinically Motor Complete Spinal Cord Injury.

Authors:  Enrico Rejc; Andrew C Smith; Kenneth A Weber; Beatrice Ugiliweneza; Robert J Bert; Mohammadjavad Negahdar; Maxwell Boakye; Susan J Harkema; Claudia A Angeli
Journal:  Front Syst Neurosci       Date:  2020-10-21

9.  Rethinking the Body in the Brain after Spinal Cord Injury.

Authors:  Erik Leemhuis; Valentina Giuffrida; Maria Luisa De Martino; Giuseppe Forte; Anna Pecchinenda; Luigi De Gennaro; Anna Maria Giannini; Mariella Pazzaglia
Journal:  J Clin Med       Date:  2022-01-13       Impact factor: 4.241

10.  Characterization of Spinal Sensorimotor Network Using Transcutaneous Spinal Stimulation during Voluntary Movement Preparation and Performance.

Authors:  Alexander G Steele; Darryn A Atkinson; Blesson Varghese; Jeonghoon Oh; Rachel L Markley; Dimitry G Sayenko
Journal:  J Clin Med       Date:  2021-12-18       Impact factor: 4.964

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