Literature DB >> 32766381

Effectiveness of Copper-Impregnated Solid Surfaces on Lowering Microbial Bio-Burden Levels in an Acute Care Hospital.

Piyali Chatterjee1, Marjory D Williams1, John D Coppin1, Yonhui Allton1, Hosoon Choi1, Julie Ann D Martel1, John E Zeber1,2, Richard E Nelson3,4, Curtis J Donskey5,6, Chetan Jinadatha7.   

Abstract

BACKGROUND: Microbial bio-burden on high-touch surfaces in patient rooms may lead to acquisition of health care-associated infections in acute care hospitals. This study examined the effect of a novel copper-impregnated solid material (16%-20% copper oxide in a polymer-based resin) on bacterial contamination on high-touch surfaces in patient rooms in an acute care hospital.
METHODS: Five high-touch surfaces were sampled for aerobic bacterial colonies (ABCs) 3 times per day over a 3-day period in 16 rooms with copper installed and 16 rooms with standard noncopper laminate installed on high-touch surfaces. A Bayesian multilevel negative binomial regression model was used to compare ABC plate counts from copper-impregnated surfaces with standard hospital laminate surfaces.
RESULTS: The mean and median (interquartile range [IQR]) ABC counts from copper-impregnated surfaces were 25.5 and 11 (4-27), and for standard hospital laminate surfaces they were 60.5 and 29 (10-74.3). The negative binomial regression model-estimated incidence rate for ABC counts on plates taken from copper-impregnated surfaces was 0.40 (0.21-0.70) times the incidence rate of ABC counts on plates taken from standard hospital laminate surfaces.
CONCLUSIONS: Copper-impregnated solid surfaces may reduce the level of microbial contamination on high-touch surfaces in patient rooms in the acute care environment, as our study demonstrated a decline in microbial bio-burden on samples taken from copper-impregnated compared with standard hospital laminate high-touch surfaces. Published by Oxford University Press on behalf of Infectious Diseases Society of America 2020.

Entities:  

Keywords:  copper; health care–associated infection; microbial bio-burden; no-touch disinfection

Year:  2020        PMID: 32766381      PMCID: PMC7397822          DOI: 10.1093/ofid/ofaa238

Source DB:  PubMed          Journal:  Open Forum Infect Dis        ISSN: 2328-8957            Impact factor:   3.835


  16 in total

1.  Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile: a secondary analysis of a multicentre cluster randomised controlled trial with crossover design (BETR Disinfection).

Authors:  Deverick J Anderson; Rebekah W Moehring; David J Weber; Sarah S Lewis; Luke F Chen; J Conrad Schwab; Paul Becherer; Michael Blocker; Patricia F Triplett; Lauren P Knelson; Yuliya Lokhnygina; William A Rutala; Daniel J Sexton
Journal:  Lancet Infect Dis       Date:  2018-06-04       Impact factor: 25.071

2.  Risk of acquiring antibiotic-resistant bacteria from prior room occupants.

Authors:  Susan S Huang; Rupak Datta; Richard Platt
Journal:  Arch Intern Med       Date:  2006-10-09

3.  Sustained reduction of microbial burden on common hospital surfaces through introduction of copper.

Authors:  Michael G Schmidt; Hubert H Attaway; Peter A Sharpe; Joseph John; Kent A Sepkowitz; Andrew Morgan; Sarah E Fairey; Susan Singh; Lisa L Steed; J Robert Cantey; Katherine D Freeman; Harold T Michels; Cassandra D Salgado
Journal:  J Clin Microbiol       Date:  2012-05-02       Impact factor: 5.948

4.  The antimicrobial efficacy of copper alloy furnishing in the clinical environment: a crossover study.

Authors:  T J Karpanen; A L Casey; P A Lambert; B D Cookson; P Nightingale; L Miruszenko; T S J Elliott
Journal:  Infect Control Hosp Epidemiol       Date:  2011-12-07       Impact factor: 3.254

5.  Reduced health care-associated infections in an acute care community hospital using a combination of self-disinfecting copper-impregnated composite hard surfaces and linens.

Authors:  Costi D Sifri; Gene H Burke; Kyle B Enfield
Journal:  Am J Infect Control       Date:  2016-09-28       Impact factor: 2.918

Review 6.  Antimicrobial surfaces to prevent healthcare-associated infections: a systematic review.

Authors:  M P Muller; C MacDougall; M Lim
Journal:  J Hosp Infect       Date:  2015-10-03       Impact factor: 3.926

7.  Potent bactericidal efficacy of copper oxide impregnated non-porous solid surfaces.

Authors:  Alastair B Monk; Vikram Kanmukhla; Ken Trinder; Gadi Borkow
Journal:  BMC Microbiol       Date:  2014-03-07       Impact factor: 3.605

8.  Copper-based water repellent and antibacterial coatings by aerosol assisted chemical vapour deposition.

Authors:  Ekrem Ozkan; Colin C Crick; Alaric Taylor; Elaine Allan; Ivan P Parkin
Journal:  Chem Sci       Date:  2016-04-20       Impact factor: 9.825

9.  Antimicrobial properties of a novel copper-based composite coating with potential for use in healthcare facilities.

Authors:  David A Montero; Carolina Arellano; Mirka Pardo; Rosa Vera; Ricardo Gálvez; Marcela Cifuentes; María A Berasain; Marisol Gómez; Claudio Ramírez; Roberto M Vidal
Journal:  Antimicrob Resist Infect Control       Date:  2019-01-05       Impact factor: 4.887

10.  Evaluation of a pulsed-xenon ultraviolet room disinfection device for impact on contamination levels of methicillin-resistant Staphylococcus aureus.

Authors:  Chetan Jinadatha; Ricardo Quezada; Thomas W Huber; Jason B Williams; John E Zeber; Laurel A Copeland
Journal:  BMC Infect Dis       Date:  2014-04-07       Impact factor: 3.090

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  1 in total

Review 1.  Copper Surfaces in Biofilm Control.

Authors:  Inês B Gomes; Manuel Simões; Lúcia C Simões
Journal:  Nanomaterials (Basel)       Date:  2020-12-11       Impact factor: 5.076

  1 in total

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