Literature DB >> 32756734

Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital.

Adalberto Studart-Neto1, Bruno Fukelmann Guedes1, Raphael de Luca E Tuma1, Antonio Edvan Camelo Filho1, Gabriel Taricani Kubota1, Bruno Diógenes Iepsen1, Gabriela Pantaleão Moreira1, Júlia Chartouni Rodrigues1, Maíra Medeiros Honorato Ferrari1, Rafael Bernhart Carra1, Raphael Ribeiro Spera1, Mariana Hiromi Manoel Oku1, Sara Terrim1, Cesar Castello Branco Lopes1, Carlos Eduardo Borges Passos Neto1, Matheus Dalben Fiorentino1, Julia Carvalhinho Carlos DE Souza1, José Pedro Soares Baima1, Tomás Fraga Ferreira DA Silva1, Cristiane Araujo Martins Moreno1, Andre Macedo Serafim Silva1, Carlos Otto Heise1, Rodrigo Holanda MendonÇa1, Ida Fortini1, Jerusa Smid1,2, Tarso Adoni1,3, Marcia Rubia Rodrigues GonÇalves1, Samira Luisa Apóstolos Pereira1, Lecio Figueira Pinto1, Helio Rodrigues Gomes1,4, Edmar Zanoteli1, Sonia Maria Dozzi Brucki1, Adriana Bastos Conforto1, Luiz Henrique Martins Castro1, Ricardo Nitrini1.   

Abstract

BACKGROUND: More than one-third of COVID-19 patients present neurological symptoms ranging from anosmia to stroke and encephalopathy. Furthermore, pre-existing neurological conditions may require special treatment and may be associated with worse outcomes. Notwithstanding, the role of neurologists in COVID-19 is probably underrecognized.
OBJECTIVE: The aim of this study was to report the reasons for requesting neurological consultations by internists and intensivists in a COVID-19-dedicated hospital.
METHODS: This retrospective study was carried out at Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil, a 900-bed COVID-19 dedicated center (including 300 intensive care unit beds). COVID-19 diagnosis was confirmed by SARS-CoV-2-RT-PCR in nasal swabs. All inpatient neurology consultations between March 23rd and May 23rd, 2020 were analyzed. Neurologists performed the neurological exam, assessed all available data to diagnose the neurological condition, and requested additional tests deemed necessary. Difficult diagnoses were established in consensus meetings. After diagnosis, neurologists were involved in the treatment.
RESULTS: Neurological consultations were requested for 89 out of 1,208 (7.4%) inpatient COVID admissions during that period. Main neurological diagnoses included: encephalopathy (44.4%), stroke (16.7%), previous neurological diseases (9.0%), seizures (9.0%), neuromuscular disorders (5.6%), other acute brain lesions (3.4%), and other mild nonspecific symptoms (11.2%).
CONCLUSIONS: Most neurological consultations in a COVID-19-dedicated hospital were requested for severe conditions that could have an impact on the outcome. First-line doctors should be able to recognize neurological symptoms; neurologists are important members of the medical team in COVID-19 hospital care.

Entities:  

Mesh:

Year:  2020        PMID: 32756734     DOI: 10.1590/0004-282x20200089

Source DB:  PubMed          Journal:  Arq Neuropsiquiatr        ISSN: 0004-282X            Impact factor:   1.420


  13 in total

1.  Neurohospitalist Practice and Well-Being During the COVID-19 Pandemic.

Authors:  Tarini Goyal; John C Probasco; Carl A Gold; Joshua P Klein; Natalie R Weathered; Kiran T Thakur
Journal:  Neurohospitalist       Date:  2021-05-12

Review 2.  Peripheral Nervous System Manifestations Associated with COVID-19.

Authors:  Sasan Andalib; José Biller; Mario Di Napoli; Narges Moghimi; Louise D McCullough; Clio A Rubinos; Christa O'Hana Nobleza; M Reza Azarpazhooh; Luciana Catanese; Isabel Elicer; Mostafa Jafari; Fabrizio Liberati; Claudia Camejo; Michel Torbey; Afshin A Divani
Journal:  Curr Neurol Neurosci Rep       Date:  2021-02-14       Impact factor: 5.081

3.  Anosmia and dysgeusia in SARS-CoV-2 infection: incidence and effects on COVID-19 severity and mortality, and the possible pathobiology mechanisms - a systematic review and meta-analysis.

Authors:  Endang Mutiawati; Marhami Fahriani; Sukamto S Mamada; Jonny Karunia Fajar; Andri Frediansyah; Helnida Anggun Maliga; Muhammad Ilmawan; Talha Bin Emran; Youdiil Ophinni; Ichsan Ichsan; Nasrul Musadir; Ali A Rabaan; Kuldeep Dhama; Syahrul Syahrul; Firzan Nainu; Harapan Harapan
Journal:  F1000Res       Date:  2021-01-21

4.  Neurological manifestations of patients with mild-to-moderate COVID-19 attending a public hospital in Lima, Peru.

Authors:  Marco H Carcamo Garcia; Diego D Garcia Choza; Brenda J Salazar Linares; Monica M Diaz
Journal:  eNeurologicalSci       Date:  2021-04-14

5.  Visual evoked potential and nerve conduction study findings in patients recovered from COVID-19.

Authors:  Asli Koskderelioglu; Neslihan Eskut; Pinar Ortan; Hulya Ozkan Ozdemir; Selma Tosun
Journal:  Neurol Sci       Date:  2022-01-14       Impact factor: 3.830

6.  Approaches to understanding COVID-19 and its neurological associations.

Authors:  Ettore Beghi; Benedict D Michael; Tom Solomon; Erica Westenberg; Andrea S Winkler
Journal:  Ann Neurol       Date:  2021-04-09       Impact factor: 10.422

Review 7.  New-Onset Movement Disorders Associated with COVID-19.

Authors:  Pedro Renato P Brandão; Talyta C Grippe; Danilo A Pereira; Renato P Munhoz; Francisco Cardoso
Journal:  Tremor Other Hyperkinet Mov (N Y)       Date:  2021-07-08

8.  Clinical, cerebrospinal fluid, and neuroimaging findings in COVID-19 encephalopathy: a case series.

Authors:  Raphael L Tuma; Bruno F Guedes; Rafael Carra; Bruno Iepsen; Júlia Rodrigues; Antonio Edvan Camelo-Filho; Gabriel Kubota; Maíra Ferrari; Adalberto Studart-Neto; Mariana Hiromi Oku; Sara Terrim; Cesar C B Lopes; Carlos E B Passos Neto; Matheus D Fiorentino; Julia C C Souza; José Pedro S Baima; Tomás Silva; Iago Perissinotti; Maria da Graça M Martin; Marcia Gonçalves; Ida Fortini; Jerusa Smid; Tarso Adoni; Leandro Lucato; Ricardo Nitrini; Hélio Gomes; Luiz H Castro
Journal:  Neurol Sci       Date:  2021-01-07       Impact factor: 3.830

Review 9.  Citicoline and COVID-19-Related Cognitive and Other Neurologic Complications.

Authors:  Yuda Turana; Michael Nathaniel; Robert Shen; Soegianto Ali; Rajender R Aparasu
Journal:  Brain Sci       Date:  2021-12-31

10.  Is loss of smell an early predictor of COVID-19 severity: a systematic review and meta-analysis.

Authors:  Sujata Purja; Hocheol Shin; Ji-Yun Lee; EunYoung Kim
Journal:  Arch Pharm Res       Date:  2021-07-24       Impact factor: 6.010

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