Literature DB >> 32741479

Advances in the Medical Treatment of Cushing Disease.

Nicholas A Tritos1, Beverly M K Biller2.   

Abstract

Medical therapy has an adjunctive role in management of Cushing disease. Medical therapy is recommended for patients who received pituitary radiotherapy and are awaiting its salutary effects. Medications are used preoperatively to stabilize the condition of seriously ill patients before surgery. Medical therapy is used to control hypercortisolism in patients with uncertain tumor location. Medical therapies available for management of patients with Cushing disease include steroidogenesis inhibitors, centrally acting agents, and glucocorticoid receptor antagonists. All agents require careful monitoring to optimize clinical effectiveness and manage adverse effects. Novel agents in development may expand the armamentarium for management of this condition.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cabergoline; Cushing disease; Etomidate; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Pasireotide

Mesh：

Substances：

Year:  2020        PMID： 32741479     DOI： 10.1016/j.ecl.2020.05.003

Source DB:  PubMed          Journal:  Endocrinol Metab Clin North Am        ISSN： 0889-8529            Impact factor:   4.741


  8 in total

1.  The effects of daily mitotane or diazepam treatment on the formation of chronic stress symptoms in newly captured wild house sparrows.

Authors:  Clare P Fischer; L Michael Romero
Journal:  Conserv Physiol       Date:  2020-12-29       Impact factor: 3.079

Review 2.  Consensus on diagnosis and management of Cushing's disease: a guideline update.

Authors:  Maria Fleseriu; Richard Auchus; Irina Bancos; Anat Ben-Shlomo; Jerome Bertherat; Nienke R Biermasz; Cesar L Boguszewski; Marcello D Bronstein; Michael Buchfelder; John D Carmichael; Felipe F Casanueva; Frederic Castinetti; Philippe Chanson; James Findling; Mônica Gadelha; Eliza B Geer; Andrea Giustina; Ashley Grossman; Mark Gurnell; Ken Ho; Adriana G Ioachimescu; Ursula B Kaiser; Niki Karavitaki; Laurence Katznelson; Daniel F Kelly; André Lacroix; Ann McCormack; Shlomo Melmed; Mark Molitch; Pietro Mortini; John Newell-Price; Lynnette Nieman; Alberto M Pereira; Stephan Petersenn; Rosario Pivonello; Hershel Raff; Martin Reincke; Roberto Salvatori; Carla Scaroni; Ilan Shimon; Constantine A Stratakis; Brooke Swearingen; Antoine Tabarin; Yutaka Takahashi; Marily Theodoropoulou; Stylianos Tsagarakis; Elena Valassi; Elena V Varlamov; Greisa Vila; John Wass; Susan M Webb; Maria C Zatelli; Beverly M K Biller
Journal:  Lancet Diabetes Endocrinol       Date:  2021-10-20       Impact factor: 32.069

3.  Levoketoconazole.

Authors:  Nicole K McCartney; Danial E Baker
Journal:  Hosp Pharm       Date:  2022-08-02

4.  The Mount Sinai Clinical Pathway for the Diagnosis and Management of Hypercortisolism due to Ectopic ACTH Syndrome.

Authors:  Eva L Alba; Emily A Japp; Gustavo Fernandez-Ranvier; Ketan Badani; Eric Wilck; Munir Ghesani; Andrea Wolf; Edward M Wolin; Virginia Corbett; David Steinmetz; Maria Skamagas; Alice C Levine
Journal:  J Endocr Soc       Date:  2022-05-06

Review 5.  Management and Medical Therapy of Mild Hypercortisolism.

Authors:  Vittoria Favero; Arianna Cremaschi; Alberto Falchetti; Agostino Gaudio; Luigi Gennari; Alfredo Scillitani; Fabio Vescini; Valentina Morelli; Carmen Aresta; Iacopo Chiodini
Journal:  Int J Mol Sci       Date:  2021-10-26       Impact factor: 5.923

Review 6.  Treatment of Cushing's syndrome with osilodrostat: practical applications of recent studies with case examples.

Authors:  Maria Fleseriu; Beverly M K Biller
Journal:  Pituitary       Date:  2022-08-24       Impact factor: 3.599

7.  Update in Cushing disease: What the neurosurgeon has to KNOW, on behalf of the EANS skull base section.

Authors:  Sayoa Eulate-Beramendi; Ainhoa Casajús; Lola Ollero; Lynnette K Niemann; Juan Carlos Fernández-Miranda; Michaël Bruneau; Moncef Berhouma; Luigi Maria Cavallo; Jan Frederick Cornelius; Roy T Daniel; Sebastien Froelich; Emmanuel Jouanneau; Ekkehard Kasper; Diego Mazzatenta; Torstein R Meling; Mahmoud Messerer; Henry W S Schroeder; Marcos Tatagiba; Massimiliano Visocchi; Eduard H Voormolen; Idoya Zazpe
Journal:  Brain Spine       Date:  2022-08-07

8.  Evaluation of FKBP5 as a cortisol activity biomarker in patients with ACTH-dependent Cushing syndrome.

Authors:  Irina Bancos; Betul Ayse Hatipoglu; Kevin C J Yuen; Lakshmi Chandramohan; Sandeep Chaudhari; Andreas G Moraitis
Journal:  J Clin Transl Endocrinol       Date:  2021-06-06
  8 in total

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