| Literature DB >> 34687601 |
Maria Fleseriu1, Richard Auchus2, Irina Bancos3, Anat Ben-Shlomo4, Jerome Bertherat5, Nienke R Biermasz6, Cesar L Boguszewski7, Marcello D Bronstein8, Michael Buchfelder9, John D Carmichael10, Felipe F Casanueva11, Frederic Castinetti12, Philippe Chanson13, James Findling14, Mônica Gadelha15, Eliza B Geer16, Andrea Giustina17, Ashley Grossman18, Mark Gurnell19, Ken Ho20, Adriana G Ioachimescu21, Ursula B Kaiser22, Niki Karavitaki23, Laurence Katznelson24, Daniel F Kelly25, André Lacroix26, Ann McCormack20, Shlomo Melmed4, Mark Molitch27, Pietro Mortini17, John Newell-Price28, Lynnette Nieman29, Alberto M Pereira6, Stephan Petersenn30, Rosario Pivonello31, Hershel Raff32, Martin Reincke33, Roberto Salvatori34, Carla Scaroni35, Ilan Shimon36, Constantine A Stratakis29, Brooke Swearingen37, Antoine Tabarin38, Yutaka Takahashi39, Marily Theodoropoulou33, Stylianos Tsagarakis40, Elena Valassi41, Elena V Varlamov42, Greisa Vila43, John Wass44, Susan M Webb45, Maria C Zatelli46, Beverly M K Biller37.
Abstract
Cushing's disease requires accurate diagnosis, careful treatment selection, and long-term management to optimise patient outcomes. The Pituitary Society convened a consensus workshop comprising more than 50 academic researchers and clinical experts to discuss the application of recent evidence to clinical practice. In advance of the virtual meeting, data from 2015 to present about screening and diagnosis; surgery, medical, and radiation therapy; and disease-related and treatment-related complications of Cushing's disease summarised in recorded lectures were reviewed by all participants. During the meeting, concise summaries of the recorded lectures were presented, followed by small group breakout discussions. Consensus opinions from each group were collated into a draft document, which was reviewed and approved by all participants. Recommendations regarding use of laboratory tests, imaging, and treatment options are presented, along with algorithms for diagnosis of Cushing's syndrome and management of Cushing's disease. Topics considered most important to address in future research are also identified.Entities:
Mesh：
Year: 2021 PMID： 34687601 PMCID： PMC8743006 DOI： 10.1016/S2213-8587(21)00235-7
Source DB: PubMed Journal: Lancet Diabetes Endocrinol ISSN： 2213-8587 Impact factor: 32.069