Literature DB >> 32735871

Behavioral testing in animal models of spinal cord injury.

K Fouad1, C Ng2, D M Basso3.   

Abstract

This review is based on a lecture presented at the Craig H. Neilsen Foundation sponsored Spinal Cord Injury Training Program at Ohio State University. We discuss the advantages and challenges of injury models in rodents and theory relation to various behavioral outcome measures. We offer strategies and advice on experimental design, behavioral testing, and on the challenges, one will encounter with animal testing. This review is designed to guide those entering the field of spinal cord injury and/or involved with in vivo animal testing.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Behavioral testing; Experimental design; Forelimb; Hindlimb; Lesion model; Rodent; Spinal cord injury; Variability

Mesh：

Year:  2020        PMID： 32735871      PMCID： PMC8325780          DOI： 10.1016/j.expneurol.2020.113410

Source DB:  PubMed          Journal:  Exp Neurol        ISSN： 0014-4886            Impact factor:   5.330


  121 in total

Review 1.  Spinal cord pattern generators for locomotion.

Authors:  V Dietz
Journal:  Clin Neurophysiol       Date:  2003-08       Impact factor: 3.708

2.  Lack of neuroprotective effects of simvastatin and minocycline in a model of cervical spinal cord injury.

Authors:  Jae H T Lee; Seth Tigchelaar; Jie Liu; Anthea M T Stammers; Femke Streijger; Wolfram Tetzlaff; Brian K Kwon
Journal:  Exp Neurol       Date:  2010-06-28       Impact factor: 5.330

3.  Pulmonary edema and hemorrhage, possible causes of pulmonary infection and respiratory failure in the early stage of lower spinal cord injury.

Authors:  Tang Yong; Yang Lili; Yuan Wen; Wang Xinwei; Zhou Xuhui
Journal:  Med Hypotheses       Date:  2012-06-08       Impact factor: 1.538

Review 4.  Exercise after spinal cord injury as an agent for neuroprotection, regeneration and rehabilitation.

Authors:  Harra R Sandrow-Feinberg; John D Houlé
Journal:  Brain Res       Date:  2015-04-09       Impact factor: 3.252

5.  Spinal cord injury-induced immune depression syndrome (SCI-IDS).

Authors:  Tino Riegger; Sabine Conrad; Kai Liu; Hermann J Schluesener; Mahdi Adibzahdeh; Jan M Schwab
Journal:  Eur J Neurosci       Date:  2007-03       Impact factor: 3.386

6.  Targeting recovery: priorities of the spinal cord-injured population.

Authors:  Kim D Anderson
Journal:  J Neurotrauma       Date:  2004-10       Impact factor: 5.269

7.  Lasting paraplegia caused by loss of lumbar spinal cord interneurons in rats: no direct correlation with motor neuron loss.

Authors:  B Hadi; Y P Zhang; D A Burke; C B Shields; D S Magnuson
Journal:  J Neurosurg       Date:  2000-10       Impact factor: 5.115

Review 8.  Autonomic consequences of spinal cord injury.

Authors:  Shaoping Hou; Alexander G Rabchevsky
Journal:  Compr Physiol       Date:  2014-10       Impact factor: 9.090

9.  Encoding of forelimb forces by corticospinal tract activity in the rat.

Authors:  Yi Guo; Richard A Foulds; Sergei V Adamovich; Mesut Sahin
Journal:  Front Neurosci       Date:  2014-05-01       Impact factor: 4.677

10.  Fecal transplant prevents gut dysbiosis and anxiety-like behaviour after spinal cord injury in rats.

Authors:  Emma K A Schmidt; Abel Torres-Espin; Pamela J F Raposo; Karen L Madsen; Kristina A Kigerl; Phillip G Popovich; Keith K Fenrich; Karim Fouad
Journal:  PLoS One       Date:  2020-01-15       Impact factor: 3.240
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  8 in total

1.  Correlation Analysis Between Magnetic Resonance Imaging-Based Anatomical Assessment and Behavioral Outcome in a Rat Contusion Model of Chronic Thoracic Spinal Cord Injury.

Authors:  Cong Xing; Zeyu Jia; Haodong Qu; Song Liu; Wang Jiang; Hao Zhong; Mi Zhou; Shibo Zhu; Guangzhi Ning; Shiqing Feng
Journal:  Front Neurosci       Date:  2022-04-21       Impact factor: 5.152

2.  Dorsal horn neuronal sparing predicts the development of at-level mechanical allodynia following cervical spinal cord injury in mice.

Authors:  Valerie Dietz; Katelyn Knox; Sherilynne Moore; Nolan Roberts; Karla Kassandra Corona; Jennifer N Dulin
Journal:  Exp Neurol       Date:  2022-03-16       Impact factor: 5.620

Review 3.  The neuroanatomical-functional paradox in spinal cord injury.

Authors:  Karim Fouad; Phillip G Popovich; Marcel A Kopp; Jan M Schwab
Journal:  Nat Rev Neurol       Date:  2020-12-11       Impact factor: 44.711

4.  Detection of locomotion deficit in a post-traumatic syringomyelia rat model using automated gait analysis technique.

Authors:  Dipak D Pukale; Mahmoud Farrag; Nic D Leipzig
Journal:  PLoS One       Date:  2021-11-11       Impact factor: 3.240

5.  Heparin-Binding Growth-Associated Molecule (Pleiotrophin) Affects Sensory Signaling and Selected Motor Functions in Mouse Model of Anatomically Incomplete Cervical Spinal Cord Injury.

Authors:  Natalia Kulesskaya; Dmitry Molotkov; Sonny Sliepen; Ekaterina Mugantseva; Arturo Garcia Horsman; Mikhail Paveliev; Heikki Rauvala
Journal:  Front Neurol       Date:  2021-12-06       Impact factor: 4.003

6.  MRI metrics at the epicenter of spinal cord injury are correlated with the stepping process in rhesus monkeys.

Authors:  Jia-Sheng Rao; Can Zhao; Shu-Sheng Bao; Ting Feng; Meng Xu
Journal:  Exp Anim       Date:  2021-11-16

7.  A modified impactor for establishing a graded contusion spinal cord injury model in rats.

Authors:  Rongbao Yan; Erliang Li; Kang Yan; Qian Zhang; Yanhua Wen; Rui Zhang; Yonghong Wu; Jin Sun; Xin Dong; Qiong Ma; Bo Liao
Journal:  Ann Transl Med       Date:  2022-04

8.  Fighting for recovery on multiple fronts: The past, present, and future of clinical trials for spinal cord injury.

Authors:  Valerie A Dietz; Nolan Roberts; Katelyn Knox; Sherilynne Moore; Michael Pitonak; Chris Barr; Jesus Centeno; Scott Leininger; Kent C New; Peter Nowell; Matthew Rodreick; Cedric G Geoffroy; Argyrios Stampas; Jennifer N Dulin
Journal:  Front Cell Neurosci       Date:  2022-09-07       Impact factor: 6.147
  8 in total

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