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Literature DB >> 327304

Relative efficiencies of a series of square-planar plantinum(II) compounds on Salmonella mutagenesis.

P Lecointe, J P Macquet, J L Butour, C Paoletti.

Abstract

Twelve Pt(II) compounds have been tested for mutagenicity on Salmonella typhimurium (strain TA 100). Very high mutagenic activities were found for the cis derivatives. A correlation is suggested between these results and a formerly described model of chemical reactivity towards DNA, according to which cis derivatives from intra-strand chelates with guanine. A smaller activity was found with monodentate complexes with DNA.

Entities: Chemical

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Year: 1977 PMID： 327304 DOI： 10.1016/0027-5107(77)90153-1

Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433

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Cited

8 in total

1. Cyto- and genotoxic effects of coordination complexes of platinum, palladium and rhodium in vitro.

Authors: J Bünger; J Stork; K Stalder
Journal: Int Arch Occup Environ Health Date: 1996 Impact factor: 3.015

2. Structures of the adducts formed between [Pt(dien)Cl]Cl and DNA in vitro.

Authors: N P Johnson; J P Macquet; J L Wiebers; B Monsarrat
Journal: Nucleic Acids Res Date: 1982-09-11 Impact factor: 16.971

3. Effect of pKM101 on cell killing and specificity of mutation induction by cis-diaminedichloroplatinum(II) in Escherichia coli K-12.

Authors: J Brouwer; M R Adhin; P van de Putte
Journal: J Bacteriol Date: 1983-12 Impact factor: 3.490

4. Base-pair substitution hotspots in GAG and GCG nucleotide sequences in Escherichia coli K-12 induced by cis-diamminedichloroplatinum (II).

Authors: J Brouwer; P van de Putte; A M Fichtinger-Schepman; J Reedijk
Journal: Proc Natl Acad Sci U S A Date: 1981-11 Impact factor: 11.205

Relative efficiencies of a series of square-planar plantinum(II) compounds on Salmonella mutagenesis.

1. Cyto- and genotoxic effects of coordination complexes of platinum, palladium and rhodium in vitro.

2. Structures of the adducts formed between [Pt(dien)Cl]Cl and DNA in vitro.

3. Effect of pKM101 on cell killing and specificity of mutation induction by cis-diaminedichloroplatinum(II) in Escherichia coli K-12.

4. Base-pair substitution hotspots in GAG and GCG nucleotide sequences in Escherichia coli K-12 induced by cis-diamminedichloroplatinum (II).

5. Influence of chromosome integrity on Escherichia coli cell division.

6. In vitro assessment of the toxicity of metal compounds : II. Mutagenesis.

7. In Vitro models and methods for bioassay and studies of cellular mechanisms.

Review 8. Effects of metals in in vitro bioassays.