Literature DB >> 32729311

Transmission modes of severe acute respiratory syndrome coronavirus 2 and implications for infection control: a review.

Sean Wei Xiang Ong1,2, Kristen K Coleman3, Po Ying Chia1,2,4, Koh Cheng Thoon3,4,5,6, Surinder Pada7, Indumathi Venkatachalam8, Dale Fisher6,9, Yian Kim Tan10, Boon Huan Tan10, Oon Tek Ng1,2,4, Brenda Sze Peng Ang1,2,4,6, Yee-Sin Leo1,2,4,6, Michelle Su Yen Wong10, Kalisvar Marimuthu1,2,6.   

Abstract

The complete picture regarding transmission modes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unknown. This review summarises the available evidence on its transmission modes, our preliminary research findings and implications for infection control policy, and outlines future research directions. Environmental contamination has been reported in hospital settings occupied by infected patients, and is higher in the first week of illness. Transmission via environmental surfaces or fomites is likely, but decontamination protocols are effective in minimising this risk. The extent of airborne transmission is also unclear. While several studies have detected SARS-CoV-2 ribonucleic acid in air samples, none has isolated viable virus in culture. Transmission likely lies on a spectrum between droplet and airborne transmission, depending on the patient, disease and environmental factors. Singapore's current personal protective equipment and isolation protocols are sufficient to manage this risk. Copyright: © Singapore Medical Association.

Entities:  

Keywords:  SARS-CoV-2; airborne; environment; infection control; transmission

Mesh:

Year:  2020        PMID: 32729311      PMCID: PMC9251227          DOI: 10.11622/smedj.2020114

Source DB:  PubMed          Journal:  Singapore Med J        ISSN: 0037-5675            Impact factor:   3.331


  57 in total

1.  The outbreak of SARS at Tan Tock Seng Hospital--relating epidemiology to control.

Authors:  Mark I C Chen; Yee-Sin Leo; Brenda S P Ang; Bee-Hoon Heng; Philip Choo
Journal:  Ann Acad Med Singapore       Date:  2006-05       Impact factor: 2.473

2.  Air, Surface Environmental, and Personal Protective Equipment Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient.

Authors:  Sean Wei Xiang Ong; Yian Kim Tan; Po Ying Chia; Tau Hong Lee; Oon Tek Ng; Michelle Su Yen Wong; Kalisvar Marimuthu
Journal:  JAMA       Date:  2020-04-28       Impact factor: 56.272

3.  Risk factors for SARS transmission from patients requiring intubation: a multicentre investigation in Toronto, Canada.

Authors:  Janet Raboud; Altynay Shigayeva; Allison McGeer; Erika Bontovics; Martin Chapman; Denise Gravel; Bonnie Henry; Stephen Lapinsky; Mark Loeb; L Clifford McDonald; Marianna Ofner; Shirley Paton; Donna Reynolds; Damon Scales; Sandy Shen; Andrew Simor; Thomas Stewart; Mary Vearncombe; Dick Zoutman; Karen Green
Journal:  PLoS One       Date:  2010-05-19       Impact factor: 3.240

4.  Evidence of airborne transmission of the severe acute respiratory syndrome virus.

Authors:  Ignatius T S Yu; Yuguo Li; Tze Wai Wong; Wilson Tam; Andy T Chan; Joseph H W Lee; Dennis Y C Leung; Tommy Ho
Journal:  N Engl J Med       Date:  2004-04-22       Impact factor: 91.245

5.  Bioaerosol concentrations generated from toilet flushing in a hospital-based patient care setting.

Authors:  Samantha D Knowlton; Corey L Boles; Eli N Perencevich; Daniel J Diekema; Matthew W Nonnenmann
Journal:  Antimicrob Resist Infect Control       Date:  2018-01-26       Impact factor: 4.887

6.  Toward understanding the risk of secondary airborne infection: emission of respirable pathogens.

Authors:  Mark Nicas; William W Nazaroff; Alan Hubbard
Journal:  J Occup Environ Hyg       Date:  2005-03       Impact factor: 2.155

7.  SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients.

Authors:  Lirong Zou; Feng Ruan; Mingxing Huang; Lijun Liang; Huitao Huang; Zhongsi Hong; Jianxiang Yu; Min Kang; Yingchao Song; Jinyu Xia; Qianfang Guo; Tie Song; Jianfeng He; Hui-Ling Yen; Malik Peiris; Jie Wu
Journal:  N Engl J Med       Date:  2020-02-19       Impact factor: 91.245

8.  Environmental contamination by SARS-CoV-2 in a designated hospital for coronavirus disease 2019.

Authors:  Songjie Wu; Ying Wang; Xuelan Jin; Jia Tian; Jianzhong Liu; Yiping Mao
Journal:  Am J Infect Control       Date:  2020-05-12       Impact factor: 2.918

9.  Absence of contamination of personal protective equipment (PPE) by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Authors:  Sean Wei Xiang Ong; Yian Kim Tan; Kalisvar Marimuthu; Michelle Su Yen Wong; Oon Tek Ng; Stephanie Sutjipto; Po Ying Chia; Barnaby Edward Young; Marcus Gum; Sok Kiang Lau; Monica Chan; Shawn Vasoo; Shehara Mendis; Boon Kiat Toh; Janice Leong; Timothy Barkham; Brenda Sze Peng Ang; Boon Huan Tan; Yee-Sin Leo
Journal:  Infect Control Hosp Epidemiol       Date:  2020-03-26       Impact factor: 3.254

10.  Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention.

Authors:  Zunyou Wu; Jennifer M McGoogan
Journal:  JAMA       Date:  2020-04-07       Impact factor: 56.272

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  4 in total

Review 1.  One Year on: An Overview of Singapore's Response to COVID-19-What We Did, How We Fared, How We Can Move Forward.

Authors:  S Vivek Anand; Yao Kang Shuy; Poay Sian Sabrina Lee; Eng Sing Lee
Journal:  Int J Environ Res Public Health       Date:  2021-08-30       Impact factor: 4.614

2.  Airborne SARS-CoV-2 surveillance in hospital environment using high-flowrate air samplers and its comparison to surface sampling.

Authors:  Alicia Xy Ang; Irvan Luhung; Bintou A Ahidjo; Daniela I Drautz-Moses; Paul A Tambyah; Chee Keng Mok; Kenny Jx Lau; Sai Meng Tham; Justin Jang Hann Chu; David M Allen; Stephan C Schuster
Journal:  Indoor Air       Date:  2021-09-14       Impact factor: 6.554

Review 3.  SARS-CoV-2 and Health Care Worker Protection in Low-Risk Settings: a Review of Modes of Transmission and a Novel Airborne Model Involving Inhalable Particles.

Authors:  X Sophie Zhang; Caroline Duchaine
Journal:  Clin Microbiol Rev       Date:  2020-10-28       Impact factor: 26.132

4.  Direct COVID-19 infection of enterocytes: The role of hypochlorhydria.

Authors:  Julia J Dibner
Journal:  Am J Infect Control       Date:  2020-08-11       Impact factor: 2.918

  4 in total

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