Literature DB >> 327284

Temperature-sensitive respiratory-deficient mitochondrial mutations: isolation and genetic mapping.

M Bolotin-Fukuhara, G Fay, H Fukuhara.   

Abstract

In order to find new genetic loci and functions on the yeast mitochondrial DNA, especially mutations affecting the mitochondrial protein synthesis apparatus, temperature sensitive mutants have been isolated after MnCl2 mutagenesis and mitochondrial and nuclear mutants classified according to their pattern of recombination with three rho- tester strains. Eighteen cold- and heat-sensitive respiratory deficient mitochondrial mutants have been isolated and localized on the mitochondrial genome by deletion mapping using 113 rho- strains. Eight of them appear to represent new loci, among which some are probably mutations of the tRNA and rRNA genes.

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Year:  1977        PMID： 327284     DOI： 10.1007/bf00693083

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  13 in total

1.  A temperature sensitive mitochondrial mutation of Saccharomyces cerevisiae.

Authors:  E M Storm; J Marmur
Journal:  Biochem Biophys Res Commun       Date:  1975-05-19       Impact factor: 3.575

2.  Assembly of the mitochondrial membrane system: isolation of nuclear and cytoplasmic mutants of Saccharomyces cerevisiae with specific defects in mitochondrial functions.

Authors:  A Tzagoloff; A Akai; R B Needleman
Journal:  J Bacteriol       Date:  1975-06       Impact factor: 3.490

3.  Localization in yeast mitochondrial DNA of mutations expressed in a deficiency of cytochrome oxidase and/or coenzyme QH2-cytochrome c reductase.

Authors:  P P Slonimski; A Tzagoloff
Journal:  Eur J Biochem       Date:  1976-01-02

4.  Properties of cytoplasmic mutants of Saccharomyces cerevisiae with specific lesions in cytochrome oxidase.

Authors:  A Tzagoloff; A Akai; R B Needleman
Journal:  Proc Natl Acad Sci U S A       Date:  1975-06       Impact factor: 11.205

5.  Induction by manganese of mitochondrial antibiotic resistance mutations in yeast.

Authors:  A Putrament; H Baranowska; W Prazmo
Journal:  Mol Gen Genet       Date:  1973-11-22

6.  A novel respiration-deficient mutant of Saccharomyces cerevisiae. I. Preliminary characterization of phenotype and mitochondrial inheritance.

Authors:  U Flury; H R Mahler; F Feldman
Journal:  J Biol Chem       Date:  1974-10-10       Impact factor: 5.157

7.  Restriction endonuclease analysis of mitochondrial DNA from grande and genetically characterized cytoplasmic petite clones of Saccharomyces cerevisiae.

Authors:  R Morimoto; A Lewin; H J Hsu; M Rabinowitz; H Fukuhara
Journal:  Proc Natl Acad Sci U S A       Date:  1975-10       Impact factor: 11.205

8.  Deletion mapping of mitochondrial transfer RNA genes in Saccharomyces cerevisiae by means of cytoplasmic petite mutants.

Authors:  H Fukuhara; M Bolotin-Fukuhara
Journal:  Mol Gen Genet       Date:  1976-04-23

9.  Evidence for an extrakaryotic mutation affecting the maintenance of the rho factor in yeast.

Authors:  A Handwerker; R J Schweyen; K Wolf; F Kaudewitz
Journal:  J Bacteriol       Date:  1973-03       Impact factor: 3.490

10.  Physical and genetic organization of petite and grande yeast mitochondrial DNA. IV. In vivo transcription products of mitochondrial DNA and localization of 23 S ribosomal RNA in petite mutants of saccharomyces cerevisiae.

Authors:  G Faye; C Kujawa; H Fukuhara
Journal:  J Mol Biol       Date:  1974-09-05       Impact factor: 5.469
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  37 in total

1.  Physical mapping and characterization of the mitochondrial DNA and RNA sequences from mit- mutants defective in cytochrome oxidase peptide 1 (OXI 3).

Authors:  R Morimoto; A Lewin; M Rabinowitz
Journal:  Mol Gen Genet       Date:  1979-02-16

2.  A point mutation in a mitochondrial tRNA gene abolishes its 3' end processing.

Authors:  E Zennaro; S Francisci; A Ragnini; L Frontali; M Bolotin-Fukuhara
Journal:  Nucleic Acids Res       Date:  1989-07-25       Impact factor: 16.971

3.  Mutational studies of the major tRNA region of the S. cerevisiae mitochondrial genome.

Authors:  N Elelj-Fridhi; C Pallier; R Zelikson; M Guetari; M Bolotin-Fukuhara
Journal:  Curr Genet       Date:  1991-04       Impact factor: 3.886

4.  Second-site antibiotic resistance mutations in the ribosomal region of yeast mitochondrial DNA.

Authors:  J A Knight; A J Courey; B Stebbins
Journal:  Curr Genet       Date:  1982-05       Impact factor: 3.886

5.  Suppression of a mitochondrial point mutation in a tRNA gene can cast light on the mechanisms of 3' end-processing.

Authors:  T Rinaldi; S Francisci; E Zennaro; L Frontali; M Bolotin-Fukuhara
Journal:  Curr Genet       Date:  1994-05       Impact factor: 3.886

6.  Nuclear and mitochondrial revertants of a yeast mitochondrial tRNA mutant.

Authors:  Y W Kang; D L Miller
Journal:  Mol Gen Genet       Date:  1988-08

7.  The genetic map of transfer RNA genes of yeast mitochondria: correction and extension.

Authors:  M Wesolowski; H Fukuhara
Journal:  Mol Gen Genet       Date:  1979-03-05

8.  Spontaneous and induced rho mutants of Saccharomyces cerevisiae: patterns of loss of mitochondrial genetic markers.

Authors:  M Heude; H Fukuhara; E Moustacchi
Journal:  J Bacteriol       Date:  1979-08       Impact factor: 3.490

9.  Restriction enzyme analysis of mitochondrial DNAs of petite mutants of yeast: classification of petites, and deletion mapping of mitochondrial genes.

Authors:  A Lewin; R Morimoto; M Rabinowitz
Journal:  Mol Gen Genet       Date:  1978-07-25

10.  Complete DNA sequence coding for the large ribosomal RNA of yeast mitochondria.

Authors:  F Sor; H Fukuhara
Journal:  Nucleic Acids Res       Date:  1983-01-25       Impact factor: 16.971
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