Literature DB >> 32705447

Pharmaceutical Benefit-Risk Perception and Age Differences in the USA and Germany.

Dominic H P Balog-Way1, Darrick Evensen2, Ragnar E Löfstedt3.   

Abstract

INTRODUCTION: Understanding how patients of all ages perceive the benefits and risks of medical treatments is vitally important. Yet, the role of older age on pharmaceutical benefit-risk perceptions has hardly been empirically investigated as a central focus of study.
OBJECTIVE: This study tested the generalizability of recent pilot findings to explore benefit-risk perception age differences between adults aged 65 years old and over (older group) and those aged 18-64 years old (younger group).
METHODS: An online survey representative for age, sex, and education was conducted in Ohio, USA (N = 1520) and Germany (N = 1536). A combination of benefit, risk, and affect questions measured respondents' perceptions of 18 medicines, tests, vaccines, and procedures. Further questions investigated general perceptions of side effects and effectiveness, as well as respondents' reliance on different sources of medicines information.
RESULTS: Clear age differences were found that strongly support recent pilot findings. Older adults perceived prescription medicines significantly more positively than their younger counterparts. They had significantly higher benefit and lower risk perceptions for most, but not all, medical treatments investigated. Older adults' benefit-risk perceptions were more strongly correlated with positive/negative affect, that is, their positive/negative experiences and feelings of "goodness" or "badness" they associated with each medical treatment investigated. They also perceived doctors and pharmacists as more competent and trustworthy. Contrary to popular belief, both age groups ranked their reliance on 15 different medical (e.g. doctors), societal (e.g. social media), industry (e.g. pharmaceutical company websites), and governmental (e.g. regulatory agencies) sources of medicines information remarkably similarly.
CONCLUSION: Age has an important role in patients' pharmaceutical benefit-risk perceptions. Findings show that, when designing messages, benefit-risk communicators should incorporate age differences. This includes older patients' positive perceptions of pharmaceuticals, greater reliance on affect, and information seeking versus scanning behaviour. Field experiments are now needed to test the effectiveness of such changes for improving benefit-risk communication practice.

Entities:  

Year:  2020        PMID: 32705447     DOI: 10.1007/s40264-020-00977-6

Source DB:  PubMed          Journal:  Drug Saf        ISSN: 0114-5916            Impact factor:   5.606


  30 in total

1.  Meta-analysis of the relationship between risk perception and health behavior: the example of vaccination.

Authors:  Noel T Brewer; Gretchen B Chapman; Frederick X Gibbons; Meg Gerrard; Kevin D McCaul; Neil D Weinstein
Journal:  Health Psychol       Date:  2007-03       Impact factor: 4.267

2.  Risk perception of prescription drugs: report on a survey in Canada.

Authors:  P Slovic; N Kraus; H Lappe; M Major
Journal:  Can J Public Health       Date:  1991 May-Jun

3.  The sciences of science communication.

Authors:  Baruch Fischhoff
Journal:  Proc Natl Acad Sci U S A       Date:  2013-08-13       Impact factor: 11.205

4.  Transparency in Europe: A Quantitative Study.

Authors:  Frederic Bouder; Dominic Way; Ragnar Löfstedt; Darrick Evensen
Journal:  Risk Anal       Date:  2015-05-01       Impact factor: 4.000

5.  The Role of Risk Perception in Flu Vaccine Behavior among African-American and White Adults in the United States.

Authors:  Vicki S Freimuth; Amelia Jamison; Gregory Hancock; Donald Musa; Karen Hilyard; Sandra Crouse Quinn
Journal:  Risk Anal       Date:  2017-03-17       Impact factor: 4.000

Review 6.  Pharmaceutical Benefit-Risk Communication Tools: A Review of the Literature.

Authors:  Dominic Way; Hortense Blazsin; Ragnar Löfstedt; Frederic Bouder
Journal:  Drug Saf       Date:  2017-01       Impact factor: 5.606

7.  Perception of risk.

Authors:  P Slovic
Journal:  Science       Date:  1987-04-17       Impact factor: 47.728

8.  Communicating uncertainties about prescription drugs to the public: a national randomized trial.

Authors:  Lisa M Schwartz; Steven Woloshin
Journal:  Arch Intern Med       Date:  2011-09-12

9.  Risk perceptions and health behavior.

Authors:  Rebecca Ferrer; William M Klein
Journal:  Curr Opin Psychol       Date:  2015-10-01

Review 10.  Does heightening risk appraisals change people's intentions and behavior? A meta-analysis of experimental studies.

Authors:  Paschal Sheeran; Peter R Harris; Tracy Epton
Journal:  Psychol Bull       Date:  2013-06-03       Impact factor: 17.737

View more
  1 in total

1.  The Evolving Field of Risk Communication.

Authors:  Dominic Balog-Way; Katherine McComas; John Besley
Journal:  Risk Anal       Date:  2020-10-20       Impact factor: 4.000

  1 in total

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