Literature DB >> 32705313

Discrimination of serous cystadenoma from mucinous cystic neoplasm and branch duct intraductal papillary mucinous neoplasm in the pancreas with CT.

Guang-Xian Wang1, Zhi-Ping Wang1, Hai-Ling Chen2, Dong Zhang1, Li Wen3.   

Abstract

PURPOSE: The imaging features of serous cystadenomas (SCAs) overlap with those of mucinous cystic neoplasms (MCNs) and branch duct intraductal papillary mucinous neoplasms (BD-IPMNs), and an accurate preoperative diagnosis is important for clinical treatment due to their different biological behaviors. The aim of this study was to provide a computed tomographic (CT) feature for the diagnosis of SCAs and estimate whether the "circumvascular sign" can contribute to the discrimination of SCAs from MCNs and BD-IPMNs.
METHODS: From August 2011 through December 2019, a total of 71 patients (30 patients with 30 SCAs, 21 patients with 21 MCNs and 20 patients with 22 BP-IPMNs) were enrolled in this study. All patients underwent CT examination and were confirmed by surgical pathology. In addition to patient clinical information, CT features (e.g., location, shape) were evaluated via CT.
RESULTS: Central scarring, central calcification and the circumvascular sign were found to be specific CT features for the diagnosis of SCAs and their differential diagnosis from MCNs and BD-IPMNs. All three CT features had high specificity, and both central scarring and central calcification had low sensitivity. When any one of these two features was combined with the circumvascular sign, the sensitivity increased to 83.3%.
CONCLUSION: Pancreatic cystic neoplasms that show central scarring, central calcification or the circumvascular sign on CT could be diagnosed as SCAs. When either of the first two features is combined with the circumvascular sign, the diagnostic sensitivity could be increased.

Entities:  

Keywords:  Branch duct intraductal papillary mucinous neoplasm; Computed tomography; Mucinous cystic neoplasm; Pancreatic cystic neoplasm; Serous cystadenoma

Year:  2020        PMID: 32705313     DOI: 10.1007/s00261-020-02664-7

Source DB:  PubMed          Journal:  Abdom Radiol (NY)


  16 in total

1.  Characterization of pancreatic serous cystadenoma on dual-phase multidetector computed tomography.

Authors:  Linda C Chu; Aatur D Singhi; Ralph H Hruban; Elliot K Fishman
Journal:  J Comput Assist Tomogr       Date:  2014 Mar-Apr       Impact factor: 1.826

Review 2.  Radiological Workup of Cystic Neoplasms of the Pancreas.

Authors:  Thomas L Bollen; Frank J Wessels
Journal:  Visc Med       Date:  2018-06-15

Review 3.  The many faces of pancreatic serous cystadenoma: Radiologic and pathologic correlation.

Authors:  L C Chu; A D Singhi; R R Haroun; R H Hruban; E K Fishman
Journal:  Diagn Interv Imaging       Date:  2016-09-07       Impact factor: 4.026

4.  Diffusion-Weighted Magnetic Resonance Imaging in Distinguishing Between Mucin-Producing and Serous Pancreatic Cysts.

Authors:  Chiara Pozzessere; Sandra Luz Castaños Gutiérrez; Celia Pamela Corona-Villalobos; Lorenzo Righi; Chunmiao Xu; Anne Marie Lennon; Christopher L Wolfgang; Ralph H Hruban; Michael Goggins; Marcia I Canto; Ihab R Kamel
Journal:  J Comput Assist Tomogr       Date:  2016 Jul-Aug       Impact factor: 1.826

Review 5.  ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts.

Authors:  Grace H Elta; Brintha K Enestvedt; Bryan G Sauer; Anne Marie Lennon
Journal:  Am J Gastroenterol       Date:  2018-02-27       Impact factor: 10.864

6.  Discrimination of unilocular macrocystic serous cystadenoma from pancreatic pseudocyst and mucinous cystadenoma with CT: initial observations.

Authors:  Frank Cohen-Scali; Valérie Vilgrain; Giuseppe Brancatelli; Pascal Hammel; Marie-Pierre Vullierme; Alain Sauvanet; Yves Menu
Journal:  Radiology       Date:  2003-09       Impact factor: 11.105

Review 7.  Cystic Pancreatic Tumors.

Authors:  Kristine S Burk; David Knipp; Dushyant V Sahani
Journal:  Magn Reson Imaging Clin N Am       Date:  2018-08       Impact factor: 2.266

8.  A prospective study on endoscopic ultrasound for the differential diagnosis of serous cystic neoplasms and mucinous cystic neoplasms.

Authors:  Lisen Zhong; Ningli Chai; Enqiang Linghu; Huikai Li; Jing Yang; Ping Tang
Journal:  BMC Gastroenterol       Date:  2019-07-16       Impact factor: 3.067

9.  Differential diagnosis of pancreatic serous cystadenoma and mucinous cystadenoma: utility of textural features in combination with morphological characteristics.

Authors:  Jing Yang; Xinli Guo; Hao Zhang; Weiwei Zhang; Jinen Song; Hui Xu; Xuelei Ma
Journal:  BMC Cancer       Date:  2019-12-16       Impact factor: 4.430

10.  Preoperative contrast-enhanced computed tomographic characterisation of pancreatic cystic lesions: A prospective study.

Authors:  Dar M Saleem; Wani A Haseeb; Arshed H Parry; Robbani Irfan; Najar M Muzaffar; Gojwari Tariq; Shah O Javed; Imza Feroz
Journal:  SA J Radiol       Date:  2019-06-10
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  2 in total

Review 1.  Cystic Neoplasms of the Pancreas: Differential Diagnosis and Radiology Correlation.

Authors:  Feixiang Hu; Yue Hu; Dan Wang; Xiaowen Ma; Yali Yue; Wei Tang; Wei Liu; Puye Wu; Weijun Peng; Tong Tong
Journal:  Front Oncol       Date:  2022-03-01       Impact factor: 6.244

Review 2.  Pancreatic Incidentaloma.

Authors:  Miłosz Caban; Ewa Małecka-Wojciesko
Journal:  J Clin Med       Date:  2022-08-09       Impact factor: 4.964

  2 in total

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