Linda C Chu1, Aatur D Singhi, Ralph H Hruban, Elliot K Fishman. 1. From the *The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD; †Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA; and ‡Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Hospital, Baltimore, MD.
Abstract
OBJECTIVE: The objective of the study was to characterize pancreatic serous cystadenomas on dual-phase multidetector computed tomography in a surgical series. MATERIALS AND METHODS: This is a retrospective review of preoperative dual-phase multidetector computed tomographic scans from 68 patients with surgically resected and pathologically confirmed pancreatic serous cystadenomas. RESULTS: Pancreatic serous cystadenomas were most commonly found in the tail (39%). The mean (SD) axial dimension was 4.5 (2.7) cm. A total of 36% contained internal calcifications. Dilatation of the main pancreatic duct (14%) and pancreatic parenchymal atrophy (11%) were uncommon. The mean (SD) attenuation of components with the highest attenuation was 49.1 (35.0) Hounsfield units on the arterial phase and 48.5 (33.4) Hounsfield units on the portal venous phase. Only 20% of neoplasms demonstrated "classic" morphology, as defined by multiple thin nonenhancing septations, calcifications, as well as the absence of main pancreatic duct dilatation and vascular involvement. CONCLUSIONS: Only 20% of surgically resected serous cystadenomas fulfilled classic morphology. Attenuation was helpful in differentiating serous cystadenomas from insulinomas and other cystic pancreatic masses, but it was not helpful in differentiation from pancreatic adenocarcinomas. Morphologic features were more helpful in differentiating serous cystadenomas from malignant masses.
OBJECTIVE: The objective of the study was to characterize pancreatic serous cystadenomas on dual-phase multidetector computed tomography in a surgical series. MATERIALS AND METHODS: This is a retrospective review of preoperative dual-phase multidetector computed tomographic scans from 68 patients with surgically resected and pathologically confirmed pancreatic serous cystadenomas. RESULTS:Pancreatic serous cystadenomas were most commonly found in the tail (39%). The mean (SD) axial dimension was 4.5 (2.7) cm. A total of 36% contained internal calcifications. Dilatation of the main pancreatic duct (14%) and pancreatic parenchymal atrophy (11%) were uncommon. The mean (SD) attenuation of components with the highest attenuation was 49.1 (35.0) Hounsfield units on the arterial phase and 48.5 (33.4) Hounsfield units on the portal venous phase. Only 20% of neoplasms demonstrated "classic" morphology, as defined by multiple thin nonenhancing septations, calcifications, as well as the absence of main pancreatic duct dilatation and vascular involvement. CONCLUSIONS: Only 20% of surgically resected serous cystadenomas fulfilled classic morphology. Attenuation was helpful in differentiating serous cystadenomas from insulinomas and other cystic pancreatic masses, but it was not helpful in differentiation from pancreatic adenocarcinomas. Morphologic features were more helpful in differentiating serous cystadenomas from malignant masses.
Authors: Raghunandan Venkat; Barish H Edil; Richard D Schulick; Anne O Lidor; Martin A Makary; Christopher L Wolfgang Journal: Ann Surg Date: 2012-06 Impact factor: 12.969
Authors: Jean-Yves Mabrut; Laureano Fernandez-Cruz; Juan Santiago Azagra; Claudio Bassi; Georges Delvaux; Joseph Weerts; Jean-Michel Fabre; Jean Boulez; Jacques Baulieux; Jean-Louis Peix; Jean-François Gigot Journal: Surgery Date: 2005-06 Impact factor: 3.982
Authors: Sang Youn Kim; Jeong Min Lee; Se Hyung Kim; Kyung-Sook Shin; Young Jun Kim; Su Kyung An; Chang Jin Han; Joon Koo Han; Byung Ihn Choi Journal: AJR Am J Roentgenol Date: 2006-11 Impact factor: 3.959
Authors: Charles Galanis; Amir Zamani; John L Cameron; Kurtis A Campbell; Keith D Lillemoe; David Caparrelli; David Chang; Ralph H Hruban; Charles J Yeo Journal: J Gastrointest Surg Date: 2007-07 Impact factor: 3.452
Authors: Christoph F Dietrich; Yi Dong; Christian Jenssen; Valentina Ciaravino; Michael Hocke; Wen-Ping Wang; Eike Burmester; Kathleen Moeller; Nathan Ss Atkinson; Paola Capelli; Mirko D'Onofrio Journal: World J Gastroenterol Date: 2017-08-14 Impact factor: 5.742