Literature DB >> 327019

C6: synthesis by the liver in vivo.

M J Hobart, P J Lachmann, R Y Calne.   

Abstract

The allotype of the sixth component of complement was determined in a patient before and after liver transplantation. The C6 phenotype changed from A before transplantation to B (the donor phenotype) within 10 days of the transplant and remained wholly of the donor phenotype at 17 wk. This demonstrates that the liver is the exclusive or predominant site of C6 synthesis in vivo in man.

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Year:  1977        PMID: 327019      PMCID: PMC2180766          DOI: 10.1084/jem.146.2.629

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  3 in total

1.  Rheumatoid arthritis. Biosynthesis of complement proteins by synovial tissues.

Authors:  S Ruddy; H R Colten
Journal:  N Engl J Med       Date:  1974-06-06       Impact factor: 91.245

2.  Formation of C'-6 by rabbit liver tissue in vitro.

Authors:  U Rother; G J Thorbecke; V J Stecher-Levin; J Hurlimann; K Rother
Journal:  Immunology       Date:  1968-05       Impact factor: 7.397

3.  Human C'3: evidence for the liver as the primary site of synthesis.

Authors:  C A Alper; A M Johnson; A G Birtch; F D Moore
Journal:  Science       Date:  1969-01-17       Impact factor: 47.728

  3 in total
  11 in total

Review 1.  Modulation of complement membrane attack by local C7 synthesis.

Authors:  R Würzner
Journal:  Clin Exp Immunol       Date:  2000-07       Impact factor: 4.330

2.  Complement-subcomponent-C1-inhibitor synthesis by human monocytes.

Authors:  A C Yeung Laiwah; L Jones; A O Hamilton; K Whaley
Journal:  Biochem J       Date:  1985-02-15       Impact factor: 3.857

3.  Isohemagglutinins of graft origin after ABO-unmatched liver transplantation.

Authors:  G Ramsey; J Nusbacher; T E Starzl; G D Lindsay
Journal:  N Engl J Med       Date:  1984-11-01       Impact factor: 91.245

Review 4.  The membrane attack complex.

Authors:  H J Müller-Eberhard
Journal:  Springer Semin Immunopathol       Date:  1984

5.  Polymorphism of the sixth component of complement (C6) in the dog.

Authors:  J E Anderson; W C Ladiges; E R Giblett; P Weiden; R Storb
Journal:  Biochem Genet       Date:  1983-02       Impact factor: 1.890

6.  Cyclic nucleotides and their relationship to complement-component-C2 synthesis by human monocytes.

Authors:  D Lappin; D W Riches; B Damerau; K Whaley
Journal:  Biochem J       Date:  1984-09-01       Impact factor: 3.857

7.  Tissue-specific and ubiquitous expression patterns from alternative promoters of human genes.

Authors:  Edwin Jacox; Valer Gotea; Ivan Ovcharenko; Laura Elnitski
Journal:  PLoS One       Date:  2010-08-18       Impact factor: 3.240

8.  Biosynthesis of complement components by cultured rat hepatocytes.

Authors:  R Anthony; L Morrison; R N MacSween; K Whaley
Journal:  Biochem J       Date:  1985-11-15       Impact factor: 3.857

9.  Synthesis of human plasminogen by the liver.

Authors:  D Raum; D Marcus; C A Alper; R Levey; P D Taylor; T E Starzl
Journal:  Science       Date:  1980-05-30       Impact factor: 47.728

10.  Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis.

Authors:  Iliana Michailidou; Aldo Jongejan; Jeroen P Vreijling; Theodosia Georgakopoulou; Marit B de Wissel; Ruud A Wolterman; Patrick Ruizendaal; Ngaisah Klar-Mohamad; Anita E Grootemaat; Daisy I Picavet; Vinod Kumar; Cees van Kooten; Trent M Woodruff; B Paul Morgan; Nicole N van der Wel; Valeria Ramaglia; Kees Fluiter; Frank Baas
Journal:  Acta Neuropathol Commun       Date:  2018-05-03       Impact factor: 7.801

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