Literature DB >> 4883617

Human C'3: evidence for the liver as the primary site of synthesis.

C A Alper, A M Johnson, A G Birtch, F D Moore.   

Abstract

The liver is the primary, if not sole, site of synthesis of the third component of human complement, as shown by a change in the recipient from C'3 FS(0.6) to C'3 SS, the donor type, following homotransplantation of the liver.

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Year:  1969        PMID: 4883617     DOI: 10.1126/science.163.3864.286

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  106 in total

1.  Synthesis of factors D, B and P of the alternative pathway of complement activation, as well as of C3, by guinea-pig peritoneal macrophages in vitro.

Authors:  C Bentley; W Fries; V Brade
Journal:  Immunology       Date:  1978-12       Impact factor: 7.397

2.  Homozygous hereditary C3 deficiency due to a premature stop codon.

Authors:  Edimara Da Silva Reis; Gisele Vanessa Baracho; Adriana Sousa Lima; Chuck S Farah; Lourdes Isaac
Journal:  J Clin Immunol       Date:  2002-11       Impact factor: 8.317

Review 3.  The effect of locally synthesised complement on acute renal allograft rejection.

Authors:  Steven Sacks; Wuding Zhou
Journal:  J Mol Med (Berl)       Date:  2003-06-25       Impact factor: 4.599

4.  C-reactive protein-mediated vascular injury requires complement.

Authors:  Fadi G Hage; Suzanne Oparil; Dongqi Xing; Yiu-Fai Chen; Mark A McCrory; Alexander J Szalai
Journal:  Arterioscler Thromb Vasc Biol       Date:  2010-03-25       Impact factor: 8.311

5.  Safety profile after prolonged C3 inhibition.

Authors:  Edimara S Reis; Nadja Berger; Xin Wang; Sophia Koutsogiannaki; Robert K Doot; Justin T Gumas; Periklis G Foukas; Ranillo R G Resuello; Joel V Tuplano; David Kukis; Alice F Tarantal; Anthony J Young; Tetsuhiro Kajikawa; Athena M Soulika; Dimitrios C Mastellos; Despina Yancopoulou; Ali-Reza Biglarnia; Markus Huber-Lang; George Hajishengallis; Bo Nilsson; John D Lambris
Journal:  Clin Immunol       Date:  2018-10-10       Impact factor: 3.969

6.  Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis.

Authors:  Michael G Barnes; Alexei A Grom; Susan D Thompson; Thomas A Griffin; Paul Pavlidis; Lukasz Itert; Ndate Fall; Dawn Paxson Sowders; Claas H Hinze; Bruce J Aronow; Lorie K Luyrink; Shweta Srivastava; Norman T Ilowite; Beth S Gottlieb; Judyann C Olson; David D Sherry; David N Glass; Robert A Colbert
Journal:  Arthritis Rheum       Date:  2009-07

7.  Cis- and trans-acting elements required for constitutive and cytokine-regulated expression of the mouse complement C3 gene.

Authors:  N Kawamura; L Singer; R A Wetsel; H R Colten
Journal:  Biochem J       Date:  1992-05-01       Impact factor: 3.857

8.  Cellular specificity of murine renal C3 expression in two models of inflammation.

Authors:  B H Ault; H R Colten
Journal:  Immunology       Date:  1994-04       Impact factor: 7.397

9.  Complement C3 gene expression and regulation in human glomerular epithelial cells.

Authors:  S H Sacks; W Zhou; A Pani; R D Campbell; J Martin
Journal:  Immunology       Date:  1993-07       Impact factor: 7.397

10.  Fifteen years of clinical liver transplantation.

Authors:  T E Starzl; L J Koep; C G Halgrimson; J Hood; G P Schroter; K A Porter; R Weil
Journal:  Gastroenterology       Date:  1979-08       Impact factor: 22.682

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