Melis Deniz1, Hasan Tezer1. 1. Department of Pediatric Infectious Diseases, Faculty of Medicine, Gazi University, Ankara, Turkey.
Abstract
OBJECTIVE: The aim of this study is to review the current evidence on the vertical transmission of SARS CoV-2. METHODS: Combination of the following keywords; COVID-19, SARS CoV-2, placenta, vertical transmission, intrauterine infection, breast milk were searched in databases. RESULTS: In the 50 studies included, 17 newborns testing positive for SARS CoV-2 by RT-PCR were reported. In three neonates, SARS-CoV-2 IgG and IgM levels were elevated. Eight placental tissues testing positive for the virus were reported. Three positive RT-PCR results of test of breast milk have been reported recently. One amniotic fluid testing positive was reported. CONCLUSION: Possible vertical transmission of SARS CoV-2 has been observed in some studies currently. More RT-PCR tests on amniotic fluid, placenta, breast milk and cord blood are required.
OBJECTIVE: The aim of this study is to review the current evidence on the vertical transmission of SARS CoV-2. METHODS: Combination of the following keywords; COVID-19, SARS CoV-2, placenta, vertical transmission, intrauterine infection, breast milk were searched in databases. RESULTS: In the 50 studies included, 17 newborns testing positive for SARS CoV-2 by RT-PCR were reported. In three neonates, SARS-CoV-2 IgG and IgM levels were elevated. Eight placental tissues testing positive for the virus were reported. Three positive RT-PCR results of test of breast milk have been reported recently. One amniotic fluid testing positive was reported. CONCLUSION: Possible vertical transmission of SARS CoV-2 has been observed in some studies currently. More RT-PCR tests on amniotic fluid, placenta, breast milk and cord blood are required.
Authors: Patricia E Lee; Robert Kozak; Nasrin Alavi; Hamza Mbareche; Rose C Kung; Kellie E Murphy; Darian Perruzza; Stephanie Jarvi; Elsa Salvant; Noor Niyar N Ladhani; Albert J M Yee; Louise-Helene Gagnon; Richard Jenkinson; Grace Y Liu Journal: CMAJ Open Date: 2022-05-24
Authors: Luca Gianaroli; Baris Ata; Kersti Lundin; Satu Rautakallio-Hokkanen; Juha S Tapanainen; Nathalie Vermeulen; Anna Veiga; Edgar Mocanu Journal: Hum Reprod Date: 2021-01-25 Impact factor: 6.918