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Literature DB >> 32693057

Hematopoietic Stem Cell Metabolism during Development and Aging.

Ayako Nakamura-Ishizu¹, Keisuke Ito², Toshio Suda³.

Abstract

Cellular metabolism in hematopoietic stem cells (HSCs) is an area of intense research interest, but the metabolic requirements of HSCs and their adaptations to their niches during development have remained largely unaddressed. Distinctive from other tissue stem cells, HSCs transition through multiple hematopoietic sites during development. This transition requires drastic metabolic shifts, insinuating the capacity of HSCs to meet the physiological demand of hematopoiesis. In this review, we highlight how mitochondrial metabolism determines HSC fate, and especially focus on the links between mitochondria, endoplasmic reticulum (ER), and lysosomes in HSC metabolism.

Entities: Chemical Disease Gene Species

Year: 2020 PMID： 32693057 PMCID： PMC7418032 DOI： 10.1016/j.devcel.2020.06.029

Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270

185 in total

1. Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors.

Authors: Simon Haas; Jenny Hansson; Daniel Klimmeck; Dirk Loeffler; Lars Velten; Hannah Uckelmann; Stephan Wurzer; Áine M Prendergast; Alexandra Schnell; Klaus Hexel; Rachel Santarella-Mellwig; Sandra Blaszkiewicz; Andrea Kuck; Hartmut Geiger; Michael D Milsom; Lars M Steinmetz; Timm Schroeder; Andreas Trumpp; Jeroen Krijgsveld; Marieke A G Essers
Journal: Cell Stem Cell Date: 2015-08-20 Impact factor: 24.633

2. Improving the Accuracy of Flow Cytometric Assessment of Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells Through the Inhibition of Efflux Pumps.

Authors: Claudia Morganti; Massimo Bonora; Keisuke Ito
Journal: J Vis Exp Date: 2019-07-30 Impact factor: 1.355

Review 3. Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing.

Authors: Navdeep S Chandel; Heinrich Jasper; Theodore T Ho; Emmanuelle Passegué
Journal: Nat Cell Biol Date: 2016-07-18 Impact factor: 28.824

Review 4. Oxidative stress and hypoxia in normal and leukemic stem cells.

Authors: Ugo Testa; Catherine Labbaye; Germana Castelli; Elvira Pelosi
Journal: Exp Hematol Date: 2016-05-12 Impact factor: 3.084

Review 5. Cytochrome c: An extreme multifunctional protein with a key role in cell fate.

Authors: Roberto Santucci; Federica Sinibaldi; Paola Cozza; Fabio Polticelli; Laura Fiorucci
Journal: Int J Biol Macromol Date: 2019-06-25 Impact factor: 6.953

Review 6. Autophagy in stem cell aging.

Authors: Miren Revuelta; Ander Matheu
Journal: Aging Cell Date: 2017-08-07 Impact factor: 9.304

7. Autophagy maintains the metabolism and function of young and old stem cells.

Authors: Theodore T Ho; Matthew R Warr; Emmalee R Adelman; Olivia M Lansinger; Johanna Flach; Evgenia V Verovskaya; Maria E Figueroa; Emmanuelle Passegué
Journal: Nature Date: 2017-03-01 Impact factor: 49.962

8. DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass.

Authors: Giulia Favaro; Vanina Romanello; Tatiana Varanita; Maria Andrea Desbats; Valeria Morbidoni; Caterina Tezze; Mattia Albiero; Marta Canato; Gaia Gherardi; Diego De Stefani; Cristina Mammucari; Bert Blaauw; Simona Boncompagni; Feliciano Protasi; Carlo Reggiani; Luca Scorrano; Leonardo Salviati; Marco Sandri
Journal: Nat Commun Date: 2019-06-12 Impact factor: 14.919

9. Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy.

Authors: Madhusudhanan Sukumar; Jie Liu; Gautam U Mehta; Shashank J Patel; Rahul Roychoudhuri; Joseph G Crompton; Christopher A Klebanoff; Yun Ji; Peng Li; Zhiya Yu; Greg D Whitehill; David Clever; Robert L Eil; Douglas C Palmer; Suman Mitra; Mahadev Rao; Keyvan Keyvanfar; David S Schrump; Ena Wang; Francesco M Marincola; Luca Gattinoni; Warren J Leonard; Pawel Muranski; Toren Finkel; Nicholas P Restifo
Journal: Cell Metab Date: 2015-12-08 Impact factor: 27.287

10. Developmental trajectory of prehematopoietic stem cell formation from endothelium.

Authors: Qin Zhu; Peng Gao; Joanna Tober; Laura Bennett; Changya Chen; Yasin Uzun; Yan Li; Elizabeth D Howell; Melanie Mumau; Wenbao Yu; Bing He; Nancy A Speck; Kai Tan
Journal: Blood Date: 2020-08-13 Impact factor: 25.476

36 in total

1. Autophagy is dispensable for the maintenance of hematopoietic stem cells in neonates.

Authors: Michihiro Hashimoto; Terumasa Umemoto; Ayako Nakamura-Ishizu; Takayoshi Matsumura; Tomomasa Yokomizo; Maiko Sezaki; Hitoshi Takizawa; Toshio Suda
Journal: Blood Adv Date: 2021-03-23

2. Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis.

Authors: Juliet R Girard; Lauren M Goins; Dung M Vuu; Mark S Sharpley; Carrie M Spratford; Shreya R Mantri; Utpal Banerjee
Journal: Elife Date: 2021-10-29 Impact factor: 8.140

Review 3. Cell Biology Meets Cell Metabolism: Energy Production Is Similar in Stem Cells and in Cancer Stem Cells in Brain and Bone Marrow.

Authors: Cornelis J F van Noorden; Barbara Breznik; Metka Novak; Amber J van Dijck; Saloua Tanan; Miloš Vittori; Urban Bogataj; Noëlle Bakker; Joseph D Khoury; Remco J Molenaar; Vashendriya V V Hira
Journal: J Histochem Cytochem Date: 2021-10-29 Impact factor: 2.479

4. TPGS-Modified Long-Circulating Liposomes Loading Ziyuglycoside I for Enhanced Therapy of Myelosuppression.

Authors: Tingting Song; Hong Wang; Yue Liu; Rongshan Cai; Dezhi Yang; Yongai Xiong
Journal: Int J Nanomedicine Date: 2021-09-14

5. Low Plasma Citrate Levels and Specific Transcriptional Signatures Associated with Quiescence of CD34⁺ Progenitors Predict Azacitidine Therapy Failure in MDS/AML Patients.

Authors: Pavla Koralkova; Monika Belickova; David Kundrat; Michaela Dostalova Merkerova; Zdenek Krejcik; Katarina Szikszai; Monika Kaisrlikova; Jitka Vesela; Pavla Vyhlidalova; Jan Stetka; Alzbeta Hlavackova; Jiri Suttnar; Patrik Flodr; Jan Stritesky; Anna Jonasova; Jaroslav Cermak; Vladimir Divoky
Journal: Cancers (Basel) Date: 2021-04-30 Impact factor: 6.639

9. CD36-Mediated Fatty Acid Oxidation in Hematopoietic Stem Cells Is a Novel Mechanism of Emergency Hematopoiesis in Response to Infection.

Authors: Maria Maryanovich; Keisuke Ito
Journal: Immunometabolism Date: 2022-03-14

Review 10. Macrophage Related Chronic Inflammation in Non-Healing Wounds.

Authors: Meirong Li; Qian Hou; Lingzhi Zhong; Yali Zhao; Xiaobing Fu
Journal: Front Immunol Date: 2021-06-16 Impact factor: 7.561