Literature DB >> 32686308

Simultaneous Detection of Carbon Monoxide and Viscosity Changes in Cells.

Jonathan A Robson1, Markéta Kubánková1, Tamzin Bond1, Rian A Hendley1, Andrew J P White1, Marina K Kuimova1, James D E T Wilton-Ely1.   

Abstract

A new family of robust, non-toxic, water-compatible ruthenium(II) vinyl probes allows the rapid, selective and sensitive detection of endogenous carbon monoxide (CO) in live mammalian cells under normoxic and hypoxic conditions. Uniquely, these probes incorporate a viscosity-sensitive BODIPY fluorophore that allows the measurement of microscopic viscosity in live cells via fluorescence lifetime imaging microscopy (FLIM) while also monitoring CO levels. This is the first example of a probe that can simultaneously detect CO alongside small viscosity changes in organelles of live cells.
© 2020 The Authors. Published by Wiley-VCH GmbH.

Entities:  

Keywords:  endogenous CO; fluorescence; ruthenium; sensing; viscosity

Year:  2020        PMID： 32686308      PMCID： PMC7756414          DOI： 10.1002/anie.202008224

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  31 in total

Review 1.  Cytoarchitecture and physical properties of cytoplasm: volume, viscosity, diffusion, intracellular surface area.

Authors:  K Luby-Phelps
Journal:  Int Rev Cytol       Date:  2000

2.  CO-releasing molecule (CORM) conjugate systems.

Authors:  Anna Christin Kautz; Peter C Kunz; Christoph Janiak
Journal:  Dalton Trans       Date:  2016-11-15       Impact factor: 4.390

3.  Mapping viscosity in cells using molecular rotors.

Authors:  Marina K Kuimova
Journal:  Phys Chem Chem Phys       Date:  2012-10-05       Impact factor: 3.676

4.  Highly Sensitive and Selective Molecular Probes for Chromo-Fluorogenic Sensing of Carbon Monoxide in Air, Aqueous Solution and Cells.

Authors:  Anita Toscani; Cristina Marín-Hernández; Jonathan A Robson; Elvin Chua; Paul Dingwall; Andrew J P White; Félix Sancenón; Cristina de la Torre; Ramón Martínez-Máñez; James D E T Wilton-Ely
Journal:  Chemistry       Date:  2019-01-09       Impact factor: 5.236

5.  A reaction-based fluorescent probe for selective imaging of carbon monoxide in living cells using a palladium-mediated carbonylation.

Authors:  Brian W Michel; Alexander R Lippert; Christopher J Chang
Journal:  J Am Chem Soc       Date:  2012-09-13       Impact factor: 15.419

6.  Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP.

Authors:  T Morita; M A Perrella; M E Lee; S Kourembanas
Journal:  Proc Natl Acad Sci U S A       Date:  1995-02-28       Impact factor: 11.205

Review 7.  Carbon monoxide--physiology, detection and controlled release.

Authors:  Stefan H Heinemann; Toshinori Hoshi; Matthias Westerhausen; Alexander Schiller
Journal:  Chem Commun (Camb)       Date:  2014-04-11       Impact factor: 6.222

8.  Rational Design of a Robust Fluorescent Probe for the Detection of Endogenous Carbon Monoxide in Living Zebrafish Embryos and Mouse Tissue.

Authors:  Keyin Liu; Xiuqi Kong; Yanyan Ma; Weiying Lin
Journal:  Angew Chem Int Ed Engl       Date:  2017-10-06       Impact factor: 15.336

Review 9.  Gasotransmitters in cancer: from pathophysiology to experimental therapy.

Authors:  Csaba Szabo
Journal:  Nat Rev Drug Discov       Date:  2015-12-18       Impact factor: 84.694

Review 10.  Heme oxygenase inhibition in cancers: possible tools and targets.

Authors:  Paulina Podkalicka; Olga Mucha; Alicja Józkowicz; Józef Dulak; Agnieszka Łoboda
Journal:  Contemp Oncol (Pozn)       Date:  2018-03-05
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  5 in total

1.  Phototoxicity of BODIPY in long-term imaging can be reduced by intramolecular motion.

Authors:  Iida Kähärä; Nikita Durandin; Polina Ilina; Alexander Efimov; Timo Laaksonen; Elina Vuorimaa-Laukkanen; Ekaterina Lisitsyna
Journal:  Photochem Photobiol Sci       Date:  2022-07-07       Impact factor: 4.328

2.  A TCF-Based Carbon Monoxide NIR-Probe without the Interference of BSA and Its Application in Living Cells.

Authors:  Yingxu Wu; Xiaojing Deng; Lan Ye; Wei Zhang; Hu Xu; Boyu Zhang
Journal:  Molecules       Date:  2022-06-28       Impact factor: 4.927

3.  Simultaneous Detection of Carbon Monoxide and Viscosity Changes in Cells.

Authors:  Jonathan A Robson; Markéta Kubánková; Tamzin Bond; Rian A Hendley; Andrew J P White; Marina K Kuimova; James D E T Wilton-Ely
Journal:  Angew Chem Int Ed Engl       Date:  2020-09-17       Impact factor: 15.336

4.  Golgi-Targeting Fluorescent Probe for Monitoring CO-Releasing Molecule-3 In Vitro and In Vivo.

Authors:  Songjiao Li; Ke Yang; Jiayu Zeng; Yiteng Ding; Dan Cheng; Longwei He
Journal:  ACS Omega       Date:  2022-03-11

5.  HydroFlipper membrane tension probes: imaging membrane hydration and mechanical compression simultaneously in living cells.

Authors:  José García-Calvo; Javier López-Andarias; Jimmy Maillard; Vincent Mercier; Chloé Roffay; Aurélien Roux; Alexandre Fürstenberg; Naomi Sakai; Stefan Matile
Journal:  Chem Sci       Date:  2022-02-03       Impact factor: 9.825
  5 in total

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