Daisuke Kawahara1, Shuichi Ozawa1,2, Kazushi Yokomachi3, Chikako Fujioka3, Tomoki Kimura1, Kazuo Awai4, Yasushi Nagata1,2. 1. Department of Radiation Oncology, Institute of Biomedical & Health Sciences, Hiroshima University, Japan. 2. Hiroshima High-Precision Radiotherapy Cancer Center, Japan. 3. Radiation Therapy Section, Division of Clinical Support, Hiroshima University Hospital, Japan. 4. Department of Radiation Oncology, Graduate School of Medicine, Hiroshima University, Japan.
Abstract
PURPOSE: The objective of this study was to assess synthesized effective atomic number (Zeff) values with a new developed tissue characteristic phantom and contrast material of varying iodine concentrations using single-source fast kilovoltage switching dual-energy CT (DECT) scanner. METHODS: A newly developed multi energy tissue characterisation CT phantom and an acrylic phantom with various iodine concentrations of were scanned using single-source fast kilovoltage switching DECT (GE-DECT) scanner. The difference between the measured and theoretical values of Zeff were evaluated. Additionally, the difference and coefficient of variation (CV) values of the theoretical and measured values were compared with values obtained with the Canon-DECT scanner that was analysed in our previous study. RESULTS: The average Zeff difference in the Multi-energy phantom was within 4.5%. The average difference of the theoretical and measured Zeff values for the acrylic phantom with variation of iodine concentration was within 3.3%. Compared to the results for the single-source Canon-DECT scanner used in our previous study, the average difference and CV of the theoretical and measured Zeff values obtained with the GE-DECT scanner were markedly smaller. CONCLUSIONS: The accuracy of the synthesized Zeff values with GE-DECT had a good agreement with the theoretical Zeff values for the Multi-Energy phantom. The GE-DECT could reduce the noise and the accuracy of the Zeff values than that with Canon-DECT for the varying iodine concentrations of contrast medium. ADVANCES IN KNOWLEDGE: The accuracy and precision of the Zeff values of the contrast medium with the GE-DECT could be sufficient with human equivalent materials.
PURPOSE: The objective of this study was to assess synthesized effective atomic number (Zeff) values with a new developed tissue characteristic phantom and contrast material of varying iodine concentrations using single-source fast kilovoltage switching dual-energy CT (DECT) scanner. METHODS: A newly developed multi energy tissue characterisation CT phantom and an acrylic phantom with various iodine concentrations of were scanned using single-source fast kilovoltage switching DECT (GE-DECT) scanner. The difference between the measured and theoretical values of Zeff were evaluated. Additionally, the difference and coefficient of variation (CV) values of the theoretical and measured values were compared with values obtained with the Canon-DECT scanner that was analysed in our previous study. RESULTS: The average Zeff difference in the Multi-energy phantom was within 4.5%. The average difference of the theoretical and measured Zeff values for the acrylic phantom with variation of iodine concentration was within 3.3%. Compared to the results for the single-source Canon-DECT scanner used in our previous study, the average difference and CV of the theoretical and measured Zeff values obtained with the GE-DECT scanner were markedly smaller. CONCLUSIONS: The accuracy of the synthesized Zeff values with GE-DECT had a good agreement with the theoretical Zeff values for the Multi-Energy phantom. The GE-DECT could reduce the noise and the accuracy of the Zeff values than that with Canon-DECT for the varying iodine concentrations of contrast medium. ADVANCES IN KNOWLEDGE: The accuracy and precision of the Zeff values of the contrast medium with the GE-DECT could be sufficient with human equivalent materials.
Authors: Savvakis Nicolaou; Charlotte Jane Yong-Hing; Sandro Galea-Soler; Daniel J Hou; Luck Louis; Peter Munk Journal: AJR Am J Roentgenol Date: 2010-04 Impact factor: 3.959
Authors: Patrick Wohlfahrt; Christian Möhler; Volker Hietschold; Stefan Menkel; Steffen Greilich; Mechthild Krause; Michael Baumann; Wolfgang Enghardt; Christian Richter Journal: Int J Radiat Oncol Biol Phys Date: 2016-10-21 Impact factor: 7.038
Authors: Andrew N Primak; Joel G Fletcher; Terri J Vrtiska; Oleksandr P Dzyubak; John C Lieske; Molly E Jackson; James C Williams; Cynthia H McCollough Journal: Acad Radiol Date: 2007-12 Impact factor: 3.173