Zih-En Jhang1, Kuan-Lin Wu1, Chia-Bang Chen1, Yao-Li Chen2,3,4, Ping-Yi Lin2,5,3, Chen-Te Chou6,7. 1. Department of Medical Imaging, Changhua Christian Hospital, No. 135, Nan-Hsiao Street, Changhua, 500, Taiwan. 2. Transplant Medicine and Surgery Research Center, Changhua Christian Hospital, Changhua, Taiwan. 3. Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan. 4. School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. 5. Department of Nursing, Da-Yeh University, Changhua, Taiwan. 6. Department of Medical Imaging, Changhua Christian Hospital, No. 135, Nan-Hsiao Street, Changhua, 500, Taiwan. 96888@cch.org.tw. 7. School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. 96888@cch.org.tw.
Abstract
PURPOSE: To evaluate the diagnostic value of spleen stiffness (SS) via magnetic resonance elastography (MRE) in predicting esophageal varices. METHODS: From January 2016 to September 2018, we retrospectively reviewed 263 patients with esophagogastroduodenoscopy (EGD) records and available spleen and liver stiffness (LS) values from MRE. Clinical information including the underlying diseases, endoscopic grade of esophageal varices (EV) and laboratory data were collected from electronic medical records. RESULTS: In cirrhotic patients, MRE-SS was higher in those with EV than in those without. MRE-SS also showed significant association with EV in the multivariate analysis, whereas MRE-LS did not. The diagnostic performance of MRE-SS for EV in cirrhotic patients was demonstrated by the area under curve of 0.853 (cut-off value: 9.53 kPa, P < 0.001), 84.4% sensitivity and 73.7% specificity. CONCLUSION: For prediction of EV in cirrhotic patients, MRE-SS is a useful non-invasive tool and it demonstrates better diagnostic performance than MRE-LS does.
PURPOSE: To evaluate the diagnostic value of spleen stiffness (SS) via magnetic resonance elastography (MRE) in predicting esophageal varices. METHODS: From January 2016 to September 2018, we retrospectively reviewed 263 patients with esophagogastroduodenoscopy (EGD) records and available spleen and liver stiffness (LS) values from MRE. Clinical information including the underlying diseases, endoscopic grade of esophageal varices (EV) and laboratory data were collected from electronic medical records. RESULTS: In cirrhotic patients, MRE-SS was higher in those with EV than in those without. MRE-SS also showed significant association with EV in the multivariate analysis, whereas MRE-LS did not. The diagnostic performance of MRE-SS for EV in cirrhotic patients was demonstrated by the area under curve of 0.853 (cut-off value: 9.53 kPa, P < 0.001), 84.4% sensitivity and 73.7% specificity. CONCLUSION: For prediction of EV in cirrhotic patients, MRE-SS is a useful non-invasive tool and it demonstrates better diagnostic performance than MRE-LS does.
Entities:
Keywords:
Cirrhosis; Magnetic resonance elastography; Portal hypertension; Spleen stiffness; Varices
Authors: Jurgen H Runge; Anneloes E Bohte; Joanne Verheij; Valeska Terpstra; Aart J Nederveen; Karin M J van Nieuwkerk; Rob J de Knegt; Bert C Baak; Peter L M Jansen; Ralph Sinkus; Jaap Stoker Journal: Abdom Imaging Date: 2014-04
Authors: Salvador Augustin; Laura Muntaner; José T Altamirano; Antonio González; Esteban Saperas; Joan Dot; Monder Abu-Suboh; Josep R Armengol; Joan R Malagelada; Rafael Esteban; Jaime Guardia; Joan Genescà Journal: Clin Gastroenterol Hepatol Date: 2009-08-21 Impact factor: 11.382