Literature DB >> 32671729

Research on CRISPR/system in major cancers and its potential in cancer treatments.

Z Liu1,2, Z Liao3, Y Chen1, L Zhou1,2, W Huangting1,2, H Xiao4,5.   

Abstract

Cancer is a serious public health problem in the world and the prevention and control of cancer has become one of the health strategies of governments around the world. According to the data of the International Agency for Research on Cancer (IARC), about 8 million people die of cancer every year in the world. With the continuous progress of medical technology, there are many methods to treat cancer at present. However, many treatment methods have achieved different therapeutic effects, some of them have obvious toxic and side effects. Therefore, it is necessary to study simpler and more effective new therapies for alleviating pain and prolonging lifetime of patients. In this view, we focus on the application progress of CRISPR system in some major cancers and its potential in cancer treatments.

Entities:  

Keywords:  CRISPR; Cancer; Therapy

Year:  2020        PMID: 32671729     DOI: 10.1007/s12094-020-02450-3

Source DB:  PubMed          Journal:  Clin Transl Oncol        ISSN: 1699-048X            Impact factor:   3.405


  53 in total

1.  Identification of genes that are associated with DNA repeats in prokaryotes.

Authors:  Ruud Jansen; Jan D A van Embden; Wim Gaastra; Leo M Schouls
Journal:  Mol Microbiol       Date:  2002-03       Impact factor: 3.501

2.  A selective Aurora-A 5'-UTR siRNA inhibits tumor growth and metastasis.

Authors:  Chien-Hsien Lai; Ruo-Yu Chen; Hsing-Pang Hsieh; Shaw-Jenq Tsai; Kung-Chao Chang; Chia-Jui Yen; Yu-Chuan Huang; Yao-Wen Liu; Jenq-Chang Lee; Yi-Chien Lai; Liang-Yi Hung; Bo-Wen Lin
Journal:  Cancer Lett       Date:  2019-12-23       Impact factor: 8.679

Review 3.  Advancements in CRISPR/Cas9 technology-Focusing on cancer therapeutics and beyond.

Authors:  Zeenat Mirza; Sajjad Karim
Journal:  Semin Cell Dev Biol       Date:  2019-05-31       Impact factor: 7.727

4.  Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product.

Authors:  Y Ishino; H Shinagawa; K Makino; M Amemura; A Nakata
Journal:  J Bacteriol       Date:  1987-12       Impact factor: 3.490

Review 5.  CRISPR/Cas9 editing of the genome for cancer modeling.

Authors:  Alexis Guernet; Luca Grumolato
Journal:  Methods       Date:  2017-03-10       Impact factor: 3.608

Review 6.  Modeling Human Digestive Diseases With CRISPR-Cas9-Modified Organoids.

Authors:  Masayuki Fujii; Hans Clevers; Toshiro Sato
Journal:  Gastroenterology       Date:  2018-11-23       Impact factor: 22.682

Review 7.  CRISPR-based adaptive immune systems.

Authors:  Michael P Terns; Rebecca M Terns
Journal:  Curr Opin Microbiol       Date:  2011-04-29       Impact factor: 7.934

8.  Genome-scale CRISPR pooled screens.

Authors:  Neville E Sanjana
Journal:  Anal Biochem       Date:  2016-06-01       Impact factor: 3.365

9.  Oncolytic vaccinia virus combined with radiotherapy induces apoptotic cell death in sarcoma cells by down-regulating the inhibitors of apoptosis.

Authors:  Michelle J Wilkinson; Henry G Smith; Gráinne McEntee; Joan Kyula-Currie; Tim D Pencavel; David C Mansfield; Aadil A Khan; Victoria Roulstone; Andrew J Hayes; Kevin J Harrington
Journal:  Oncotarget       Date:  2016-12-06

10.  In Vivo CRISPR/Cas9 Gene Editing Corrects Retinal Dystrophy in the S334ter-3 Rat Model of Autosomal Dominant Retinitis Pigmentosa.

Authors:  Benjamin Bakondi; Wenjian Lv; Bin Lu; Melissa K Jones; Yuchun Tsai; Kevin J Kim; Rachelle Levy; Aslam Abbasi Akhtar; Joshua J Breunig; Clive N Svendsen; Shaomei Wang
Journal:  Mol Ther       Date:  2015-12-15       Impact factor: 11.454

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  2 in total

Review 1.  Nanomaterial-assisted CRISPR gene-engineering - A hallmark for triple-negative breast cancer therapeutics advancement.

Authors:  Jabeen Farheen; Narayan S Hosmane; Ruibo Zhao; Qingwei Zhao; M Zubair Iqbal; Xiangdong Kong
Journal:  Mater Today Bio       Date:  2022-10-04

Review 2.  Applications and challenges of CRISPR-Cas gene-editing to disease treatment in clinics.

Authors:  Wenyi Liu; Luoxi Li; Jianxin Jiang; Min Wu; Ping Lin
Journal:  Precis Clin Med       Date:  2021-07-10
  2 in total

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