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Literature DB >> 3264880

Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin 6.

T Satoh¹, S Nakamura, T Taga, T Matsuda, T Hirano, T Kishimoto, Y Kaziro.

Abstract

B-cell stimulatory factor 2 (BSF-2) is a lymphokine which induces the final maturation of B cells. BSF-2 acts on a variety of cells other than B cells, and moreover, expression of BSF-2 mRNA is detected in interleukin-1 beta-stimulated glioblastoma and astrocytoma cell lines. Here, we studied the function of BSF-2 on pheochromocytoma PC12 cells, a model system for induction of neuronal differentiation. PC12 cells possess specific receptors for BSF-2. The BSF-2-stimulated PC12 cells expressed the c-fos proto-oncogene transiently, and they began to change morphologically to neurite-extending cells after several days. The number of voltage-dependent Na+ channels was also increased.

Entities: Disease Gene

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Year: 1988 PMID： 3264880 PMCID： PMC363593 DOI： 10.1128/mcb.8.8.3546-3549.1988

Source DB: PubMed Journal: Mol Cell Biol ISSN： 0270-7306 Impact factor: 4.272

26 in total

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Journal: J Biol Chem Date: 1981-06-25 Impact factor: 5.157

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Journal: Proc Natl Acad Sci U S A Date: 1985-08 Impact factor: 11.205

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Authors: M E Greenberg; L A Greene; E B Ziff
Journal: J Biol Chem Date: 1985-11-15 Impact factor: 5.157

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Authors: T Hirano; K Yasukawa; H Harada; T Taga; Y Watanabe; T Matsuda; S Kashiwamura; K Nakajima; K Koyama; A Iwamatsu
Journal: Nature Date: 1986 Nov 6-12 Impact factor: 49.962

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Authors: G E Landreth; E M Shooter
Journal: Proc Natl Acad Sci U S A Date: 1980-08 Impact factor: 11.205

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Authors: T Curran; J I Morgan
Journal: Science Date: 1985-09-20 Impact factor: 47.728

8. Structure of the FBJ murine osteosarcoma virus genome: molecular cloning of its associated helper virus and the cellular homolog of the v-fos gene from mouse and human cells.

Authors: T Curran; W P MacConnell; F van Straaten; I M Verma
Journal: Mol Cell Biol Date: 1983-05 Impact factor: 4.272

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Authors: K Huff; D End; G Guroff
Journal: J Cell Biol Date: 1981-01 Impact factor: 10.539

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Authors: L A Greene
Journal: J Cell Biol Date: 1978-09 Impact factor: 10.539

75 in total

Review 1. Neuronal cell cultures: a tool for investigations in developmental neurobiology.

Authors: A Cestelli; G Savettieri; G Salemi; I Di Liegro
Journal: Neurochem Res Date: 1992-12 Impact factor: 3.996

Review 2. Cytokine interactions with adrenal medullary chromaffin cells.

Authors: Shirley A Douglas; Dharshini Sreenivasan; Fiona H Carman; Stephen J Bunn
Journal: Cell Mol Neurobiol Date: 2010-11-19 Impact factor: 5.046

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Authors: J P Doucet; S P Squinto; N G Bazan
Journal: Mol Neurobiol Date: 1990 Spring-Summer Impact factor: 5.590

10. Immunohistochemical localization of interleukin-6-like immunoreactivity to peripheral nerve-like structures in normal and inflamed human skin.

Authors: K Nordlind; L B Chin; A A Ahmed; J Brakenhoff; E Theodorsson; S Lidén
Journal: Arch Dermatol Res Date: 1996-07 Impact factor: 3.017