Literature DB >> 32647402

Novel Zinc / Tungsten Carbide Nanocomposite as Bioabsorbable Implant.

Zeyi Guan1, Chase S Linsley2, Injoo Hwang1, Gongcheng Yao3, Benjamin M Wu2,3,4,5, Xiaochun Li1,3.   

Abstract

There is a lack of bioabsorbable materials with adequate mechanical strength suitable for implant applications that provide temporary support while tissue integrity is restored, especially for pediatric applications. Bioabsorbable metals have emerged as an attractive choice due to their combination of strength, ductility, and biocompatibility in vivo. Zinc has shown great promise as a bioabsorbable metal, but the weak mechanical properties of pure zinc limit its application as an implant material. This study investigates zinc-tungsten carbide (Zn-WC) nanocomposite as a novel material for bioabsorbable metallic implants. Ultrasound-assisted powder compaction was used to fabricate Zn-WC nanocomposites. This study includes the material characterization of microstructure, microhardness, and degradability. Results showed that tungsten carbide nanoparticles enhanced the mechanical properties of Zn, and maintained the favorable corrosion rate of pure Zn. These results encourage further investigation of Zn-WC nanocomposites for biomedical applications with the ultimate goal of creating safe and efficacious bioabsorbable metallic implants for many clinical applications.

Entities:  

Keywords:  Bioabsorbable implant; Nanocomposites; Zinc

Year:  2019        PMID: 32647402      PMCID: PMC7346885          DOI: 10.1016/j.matlet.2019.127282

Source DB:  PubMed          Journal:  Mater Lett            Impact factor:   3.423


  28 in total

Review 1.  Zinc transporters and the cellular trafficking of zinc.

Authors:  David J Eide
Journal:  Biochim Biophys Acta       Date:  2006-04-18

2.  Fate of rigid fixation in pediatric craniofacial surgery.

Authors:  W E Berryhill; F L Rimell; J Ness; L Marentette; S J Haines
Journal:  Otolaryngol Head Neck Surg       Date:  1999-09       Impact factor: 3.497

3.  Evolution of the degradation mechanism of pure zinc stent in the one-year study of rabbit abdominal aorta model.

Authors:  Hongtao Yang; Cong Wang; Chaoqiang Liu; Houwen Chen; Yifan Wu; Jintao Han; Zichang Jia; Wenjiao Lin; Deyuan Zhang; Wenting Li; Wei Yuan; Hui Guo; Huafang Li; Guangxin Yang; Deling Kong; Donghui Zhu; Kazuki Takashima; Liqun Ruan; Jianfeng Nie; Xuan Li; Yufeng Zheng
Journal:  Biomaterials       Date:  2017-08-16       Impact factor: 12.479

4.  The effects of rigid fixation on craniofacial growth of rhesus monkeys.

Authors:  M J Yaremchuk; T G Fiala; F Barker; R Ragland
Journal:  Plast Reconstr Surg       Date:  1994-01       Impact factor: 4.730

Review 5.  Tungsten: an Emerging Toxicant, Alone or in Combination.

Authors:  Alicia M Bolt; Koren K Mann
Journal:  Curr Environ Health Rep       Date:  2016-12

Review 6.  An Overview of Mechanical Properties and Material Modeling of Polylactide (PLA) for Medical Applications.

Authors:  Jörgen S Bergström; Danika Hayman
Journal:  Ann Biomed Eng       Date:  2015-09-14       Impact factor: 3.934

7.  Morphological, Functional, and Biological Vascular Healing Response 6 Months After Drug-Eluting Stent Implantation: A Randomized Comparison of Three Drug-Eluting Stents.

Authors:  Tsuyoshi Nakata; Kenichi Fujii; Masashi Fukunaga; Masahiko Shibuya; Kenji Kawai; Daizo Kawasaki; Yoshiro Naito; Mitsumasa Ohyanagi; Tohru Masuyama
Journal:  Catheter Cardiovasc Interv       Date:  2015-11-03       Impact factor: 2.692

8.  In vivo corrosion behavior of Mg-Mn-Zn alloy for bone implant application.

Authors:  Liping Xu; Guoning Yu; Erlin Zhang; Feng Pan; Ke Yang
Journal:  J Biomed Mater Res A       Date:  2007-12-01       Impact factor: 4.396

9.  Migration pattern of cementless press fit cups in the presence of stabilizing screws in total hip arthroplasty.

Authors:  C Zilkens; S Djalali; B Bittersohl; T Kälicke; C N Kraft; R Krauspe; Marcus Jäger
Journal:  Eur J Med Res       Date:  2011-03-28       Impact factor: 2.175

10.  Time-dependent failure in load-bearing polymers: a potential hazard in structural applications of polylactides.

Authors:  T H Smit; T A P Engels; S H M Söntjens; L E Govaert
Journal:  J Mater Sci Mater Med       Date:  2009-11-07       Impact factor: 3.896

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  3 in total

1.  Zn-Mg-WC Nanocomposites for Bioresorbable Cardiovascular Stents: Microstructure, Mechanical Properties, Fatigue, Shelf Life, and Corrosion.

Authors:  Zeyi Guan; Chase S Linsley; Shuaihang Pan; Gongcheng Yao; Benjamin M Wu; Daniel S Levi; Xiaochun Li
Journal:  ACS Biomater Sci Eng       Date:  2021-12-29

2.  Experimental study on novel biodegradable Zn-Fe-Si alloys.

Authors:  Yuxin Zeng; Zeyi Guan; Chase S Linsley; Shuaihang Pan; Jingke Liu; Benjamin M Wu; Xiaochun Li
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2022-05-06       Impact factor: 3.405

3.  Fabrication and Characterization of In Situ Zn-TiB2 Nanocomposite.

Authors:  Zeyi Guan; Gongcheng Yao; Yuxin Zeng; Xiaochun Li
Journal:  Procedia Manuf       Date:  2020-06-23
  3 in total

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